Methods of [11c]-radiolabelling phenothiazine and phenothiazine-like compounds
    1.
    发明申请
    Methods of [11c]-radiolabelling phenothiazine and phenothiazine-like compounds 审中-公开
    [11c]放射性标记吩噻嗪和吩噻嗪类化合物的方法

    公开(公告)号:US20060275209A1

    公开(公告)日:2006-12-07

    申请号:US10573882

    申请日:2004-09-27

    CPC classification number: C07B59/00 C07D279/20

    Abstract: This invention pertains to methods of [11C]-radiolabelling “phenothiazine” and “phenothiazine-like” compounds, which have a pendant group (which is a primary amino group; a cationic primary imino group; a secondary amino group; a cationic secondary imino group; a primary imino group; or a secondary imino group), by reaction with [11C]methyl trifluoromethanesulfonate (CF3SO2O11CH3), also known as [11C]methyl triflate. This reaction converts the pendant group into a [11C]methyl-labelled pendant group. The resulting [11C]-radiolabelling product is useful, for example, as an in vivo positron emission tomography (PET) tracer, for example, for patients suffering from melanoma, the most serious form of skin cancer, and tauopathy (e.g., Alzheimer's disease). The present invention also pertains to the resulting [11C]-radiolabelling products, compositions comprising them, their use in methods of (e.g., PET) imaging, their use in methods of medical treatment and diagnosis, etc.

    Abstract translation: 本发明涉及具有侧基(其为伯氨基;阳离子性亚氨基;阳离子性亚氨基)的“[ - 11 C] - 放射标记”吩噻嗪“和”吩噻嗪样“化合物的方法 仲氨基;阳离子二次亚氨基;初级亚氨基;或仲亚氨基),通过与三氟甲磺酸酯(CF 3 SO 3)与[ 另外也称为[11 C]三氟甲磺酸甲酯。 该反应将侧基转化为[11 C]甲基标记的侧基。 所得的[11 C] - 放射性标记物可用于例如体内正电子发射断层摄影(PET)示踪剂,例如对于患有黑素瘤的患者,最严重的皮肤癌形式 ,和tau病(如阿尔茨海默病)。 本发明还涉及所得的[11 C] - 放射性标记物,包含它们的组合物,它们在(例如,PET)成像方法中的应用,它们在医学治疗和诊断方法中的应用等 。

    SPAR MOORING LINE SHARING METHOD AND SYSTEM
    3.
    发明申请
    SPAR MOORING LINE SHARING METHOD AND SYSTEM 有权
    SPAR运动线共享方法与系统

    公开(公告)号:US20120266800A1

    公开(公告)日:2012-10-25

    申请号:US13266481

    申请日:2010-04-30

    CPC classification number: B63B21/50

    Abstract: The disclosure provides a method and system of coupling end-to-end at least two existing mooring lines (12A, 12B) that are already deployed from the floating platform (56) to the seabed or other connecting structure to create a single shared line from the two lines. The shared lines then form a single looped line with both ends deployed to the subsea connections. The shared length provides enough payout of line to loosen one line sufficiently, while the other line becomes correspondingly tighter using the catenary length of the tight line. In part, the line can be loosened while the other is tightened because the lines are generally in the same overall direction to the seabed, such as in a same quadrant around the platform. Thus, the lines share their available lengths to provide the necessary payout for the repairs.

    Abstract translation: 本公开提供了一种将已经从浮动平台(56)部署到海床或其他连接结构的端到端的至少两个现有的系泊线(12A,12B)联接以创建单个共享线路的方法和系统 两条线。 然后,共享线路形成一个单独的环路,两端部署到海底连接。 共享长度提供足够的支付线路以充分松开一条线,而另一条线使用紧线的悬链线长度相应更紧。 部分地,线路可以松开,而另一条线被收紧,因为线路通常与海床相同的总体方向,例如在平台周围的同一象限中。 因此,这些线路共享其可用长度以提供必要的维修支付。

    Controller And Control Method For A Motorised Vehicle
    4.
    发明申请
    Controller And Control Method For A Motorised Vehicle 有权
    电动车控制器及控制方法

    公开(公告)号:US20110071711A1

    公开(公告)日:2011-03-24

    申请号:US12727976

    申请日:2010-03-19

    Abstract: A controller and control method for a motorised vehicle such a wheelchair are provided. The motorised vehicle has at least two driven wheels driven independently by a motor arrangement, and the controller receives a number of input signals from a user input device of the motorised vehicle. The controller comprises drive control circuitry for generating control signals for controlling the driving of the driven wheels by the motor arrangement, the control signals being dependent on the input signals. Speed assist circuitry is responsive to an indication of current consumed in driving the driven wheels to detect occurrence of a loading condition. On detection of occurrence of a loading condition, the speed assist circuitry is then arranged to boost at least one of the input signals in order to boost top speed in the presence of the loading condition. This significantly improves the control of the motorised vehicle in situations where the occurrence of the loading condition may otherwise prevent the vehicle from moving, as for example may occur when seeking to turn the vehicle at low speed.

    Abstract translation: 提供了一种用于诸如轮椅的机动车辆的控制器和控制方法。 电动车辆具有由电动机装置独立驱动的至少两个从动轮,并且控制器从电动车辆的用户输入装置接收多个输入信号。 控制器包括用于产生控制信号的驱动控制电路,用于控制由电动机装置驱动的从动轮,控制信号取决于输入信号。 速度辅助电路响应驱动驱动轮消耗的电流的指示,以检测装载状况的发生。 在检测到装载状态的发生时,速度辅助电路然后被布置成升高至少一个输入信号,以便在存在负载条件的情况下提升最高速度。 这在显着的情况下显着地改善了机动车辆的控制,例如当试图以低速转向车辆时,装载状况的发生可能妨碍车辆移动。

    Miniature tape cartridge and adaptor
    5.
    发明授权
    Miniature tape cartridge and adaptor 失效
    微型磁带盒和适配器

    公开(公告)号:US3963189A

    公开(公告)日:1976-06-15

    申请号:US476329

    申请日:1974-06-04

    CPC classification number: G11B25/066

    Abstract: A miniature tape cartridge comprising a housing for carrying an endless recording tape therein. The housing has a front end with at least one opening for access to part of the recording tape entrained therein past the opening for engagement of the tape with an external drive source for displacing the tape at a predetermined speed and to permit an external detection means to contact and detect information signals recorded on the tape. Alignment means are also provided and associated with the front end of the cartridge for positioning the tape in a predetermined plane with respect to the external detection means. Also provided is a tape adaptor for receiving the cartridge therein and for positioning same in a continuous loop tape player whereby the tape can be engaged by a drive source and detection means.

    Abstract translation: 一种微型带盒,包括用于在其中携带环形记录带的壳体。 壳体具有前端,其具有至少一个开口,用于接近夹在其中的通过开口的部分记录带,用于将带与用于以预定速度移位的外部驱动源接合,并允许外部检测装置 接触并检测记录在磁带上的信息信号。 对准装置还设置并与盒的前端相关联,用于将带定位在相对于外部检测装置的预定平面中。 还提供了一种用于在其中接收盒式磁带并用于将其定位在连续环形带式播放机中的磁带适配器,由此磁带可以由驱动源和检测装置接合。

    WIRELESS MESH NETWORK WITH PINCH POINT AND LOW BATTERY ALERTS
    6.
    发明申请
    WIRELESS MESH NETWORK WITH PINCH POINT AND LOW BATTERY ALERTS 有权
    无线网络与PIN点和低电压警报

    公开(公告)号:US20110164512A1

    公开(公告)日:2011-07-07

    申请号:US12735074

    申请日:2009-09-25

    CPC classification number: H04W8/22 H04W52/0225 H04W84/18 Y02D70/22

    Abstract: A wireless mesh network includes a plurality of wireless devices and a gateway organized in a multi hop mesh topology. Each wireless device maintains and reports radio statistics to the gateway, and also reports battery conditions of its power source. The device manager communicates with the gateway and provides an alert indicating existence of a pinch point within the mesh network based upon the radio statistics. When a low battery condition is reported by a device, the device manager determines whether loss of that device is a pinch point or will cause a pinch point, and provides a low battery alert prioritized based upon the pinch point analysis.

    Abstract translation: 无线网状网络包括多个无线设备和以多跳网格拓扑组织的网关。 每个无线设备维护和报告无线电统计信息到网关,并且还报告其电源的电池状况。 设备管理器与网关进行通信,并基于无线电统计信息提供指示网状网络内的夹点的存在的警报。 当设备报告电池电量不足时,设备管理器确定该设备的损耗是否为夹点,还是会导致夹点,并根据夹点分析提供优先级较低的电池警报。

    Controller and control method for a motorised vehicle
    9.
    发明授权
    Controller and control method for a motorised vehicle 有权
    机动车辆的控制器和控制方法

    公开(公告)号:US09211909B2

    公开(公告)日:2015-12-15

    申请号:US12727976

    申请日:2010-03-19

    Abstract: A controller and control method for a motorized vehicle such a wheelchair are provided. The motorized vehicle has at least two driven wheels driven independently by a motor arrangement, and the controller receives a number of input signals from a user input device of the motorized vehicle. The controller comprises drive control circuitry for generating control signals for controlling the driving of the driven wheels by the motor arrangement, the control signals being dependent on the input signals. Speed assist circuitry is responsive to an indication of current consumed in driving the driven wheels to detect occurrence of a loading condition. On detection of occurrence of a loading condition, the speed assist circuitry is then arranged to boost at least one of the input signals in order to boost top speed in the presence of the loading condition. This significantly improves the control of the motorized vehicle in situations where the occurrence of the loading condition may otherwise prevent the vehicle from moving, as for example may occur when seeking to turn the vehicle at low speed.

    Abstract translation: 提供了一种用于诸如轮椅的机动车辆的控制器和控制方法。 电动车辆具有由电动机装置独立驱动的至少两个从动轮,并且控制器从电动车辆的用户输入装置接收多个输入信号。 控制器包括用于产生控制信号的驱动控制电路,用于控制由电动机装置驱动的从动轮,控制信号取决于输入信号。 速度辅助电路响应驱动驱动轮消耗的电流的指示,以检测装载状况的发生。 在检测到装载状态的发生时,速度辅助电路然后被布置成升高至少一个输入信号,以便在存在负载条件的情况下提升最高速度。 这在显着的情况下显着地改善了机动车辆的控制,例如当试图以低速转向车辆时,装载状况的发生可能阻止车辆移动。

    Spar mooring line sharing method and system
    10.
    发明授权
    Spar mooring line sharing method and system 有权
    Spar系泊线共享方法和系统

    公开(公告)号:US08757077B2

    公开(公告)日:2014-06-24

    申请号:US13266481

    申请日:2010-04-30

    CPC classification number: B63B21/50

    Abstract: The disclosure provides a method and system of coupling end-to-end at least two existing mooring lines (12A, 12B) that are already deployed from the floating platform (56) to the seabed or other connecting structure to create a single shared line from the two lines. The shared lines then form a single looped line with both ends deployed to the subsea connections. The shared length provides enough payout of line to loosen one line sufficiently, while the other line becomes correspondingly tighter using the catenary length of the tight line. In part, the line can be loosened while the other is tightened because the lines are generally in the same overall direction to the seabed, such as in a same quadrant around the platform. Thus, the lines share their available lengths to provide the necessary payout for the repairs.

    Abstract translation: 本公开提供了一种将已经从浮动平台(56)部署到海床或其他连接结构的端到端的至少两个现有的系泊线(12A,12B)联接以创建单个共享线路的方法和系统 两条线。 然后,共享线路形成一个单独的环路,两端部署到海底连接。 共享长度提供足够的支付线路以充分松开一条线,而另一条线使用紧线的悬链线长度相应更紧。 部分地,线路可以松开,而另一条线被收紧,因为线路通常与海床相同的总体方向,例如在平台周围的同一象限中。 因此,这些线路共享其可用长度以提供必要的维修支付。

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