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公开(公告)号:US20070249063A1
公开(公告)日:2007-10-25
申请号:US11214012
申请日:2005-08-30
IPC分类号: G01N33/543 , C12Q1/68
CPC分类号: G01N33/54346 , G01N33/54326
摘要: Methods for detecting a biological interaction comprising administering a substrate comprising a ligand attached to the substrate wherein the ligand binds to a receptor and wherein a signal is produced. Also disclosed is a biosensor comprising a substrate and a ligand wherein the ligand is attached to the surface of the substrate and wherein the ligand preferentially binds to a receptor.
摘要翻译: 用于检测生物相互作用的方法,包括施用包含与底物连接的配体的底物,其中配体结合受体并且其中产生信号。 还公开了包含底物和配体的生物传感器,其中配体连接到底物的表面,并且其中配体优先与受体结合。
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公开(公告)号:US06414173B1
公开(公告)日:2002-07-02
申请号:US09434278
申请日:1999-11-05
申请人: Philip DeShong , Molly E. Mowery , Eric D. Soli , Amy S. Manoso , Michael C. Patterson , Christopher J. Handy , Marc-Raleigh Brescia
发明人: Philip DeShong , Molly E. Mowery , Eric D. Soli , Amy S. Manoso , Michael C. Patterson , Christopher J. Handy , Marc-Raleigh Brescia
IPC分类号: C07F708
摘要: Hypervalent silane and siloxane reagents (preformed or generated in situ) for transmetalation in palladium catalyzed reactions with derivatives of allylic alcohols, aryl halides, electron-withdrawing aryl bromides, and aryl triflates derived from phenols are disclosed. Also disclosed are methods of preparing glycosyl azides by reaction of an azide with a silyl ester in the presence of a phoshine.
摘要翻译: 公开了用于在与由烯丙基醇,芳基卤化物,吸电子芳基溴化物和由酚衍生的芳基三氟甲磺酸酯的钯催化反应中进行金属化反应的高价硅烷和硅氧烷试剂(预制或原位产生)。 还公开了通过在磷光存在下使叠氮化物与甲硅烷基酯反应来制备糖叠氮化物的方法。
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