公开(公告)号：US06753438B2

公开(公告)日：2004-06-22

申请号：US10257507

申请日：2002-10-11

申请人： Richard Gregory Taylor ,  Stuart Leadey ,  Jean De La Croi Habimana

发明人： Richard Gregory Taylor ,  Stuart Leadey ,  Jean De La Croi Habimana

IPC分类号： C07F708

CPC分类号： C08G77/08

摘要： The specification describes preparation of materials comprising selected boron anions and processes using them as catalysts for condensation reaction of compounds having silicon-bonded hydroxy or alkoxy groups. Preferred anion compounds comprise borates incorporating quadri-substituted boron in which the substituents include highly halogenated hydrocarbon groups for example pentafluorinated phenyl groups or bis (trifluoromethyl) phenyl groups. Preferred anions are {B(C6F5)4}− and {B(C6(CF3)2H3)4}−. The specification describes condensation in presence of these materials of compounds having at least one unit according to the general formula RoaR1bR2cSiO(4−(a+b+c)/2) in which each Ro is the same or different and represents a hydroxy, alkoxy, alkoxyalkoxy or hydrocarbonoxy group having up to 10 carbon atoms, each R1 is the same or different and represents hydrogen or a monovalent substituted or unsubstituted hydrocarbon group, each R2 is the same or different and represents a divalent substituted or unsubstituted alkylene or oxyalkylene group, a has a value of 1, 2, 3 or 4, b has a value of 0, 1, 2 or 3 and c has a value of 0, 1, 2 or 3.

摘要翻译： 说明书描述了包含选定的硼阴离子的材料的制备和使用它们作为具有硅键合的羟基或烷氧基的化合物的缩合反应的催化剂的方法。 优选的阴离子化合物包括掺入四取代硼的硼酸盐，其中取代基包括高卤化烃基，例如五氟苯基或双（三氟甲基）苯基。 优选的阴离子是{B（C 6 F 5）4} - 和{B（C 6（CF 3）2 H 3）4} - 。 该说明书描述了在这些具有至少一个单元的化合物存在下，根据通式R a a a b b R 2 cSiO（4-（a + b + c）/ 2）的缩合，其中每个 R 0相同或不同，表示具有至多10个碳原子的羟基，烷氧基，烷氧基烷氧基或烃氧基，每个R 1相同或不同，表示氢或一价取代或未取代的烃基， R 2相同或不同，表示二价取代或未取代的亚烷基或氧化烯基，a的值为1,2,3或4，b的值为0,1,2或3，c为 值为0,1,2或3。

公开(公告)号：US06740765B1

公开(公告)日：2004-05-25

申请号：US10030718

申请日：2002-04-02

申请人： Ann M. Diederich ,  Ann Marie Eldridge ,  Robert J. Mills ,  Vance J. Novack

发明人： Ann M. Diederich ,  Ann Marie Eldridge ,  Robert J. Mills ,  Vance J. Novack

IPC分类号： C07F708

CPC分类号： C07C255/46 ,  C07C253/30 ,  C07C255/37 ,  C07C2601/08 ,  C07C2601/14

摘要： This invention relates to a method for preparing 4-substituted-4-cyanocyclohexane carboxylates by forming the cyclohexane ring by treating a &agr;,&agr;-bis(2-haloethyl)-4-benzeneacetonitrile with a dialkyl malonate and decarboxylating the resulting diester.

摘要翻译： 本发明涉及通过用丙二酸二烷基酯处理α，α-双（2-卤代乙基）-4-苯乙腈和使所得二酯脱羧来形成环己烷环来制备4-取代-4-氰基环己烷羧酸酯的方法。

公开(公告)号：US06541651B1

公开(公告)日：2003-04-01

申请号：US10116885

申请日：2002-04-04

申请人： Curtis J. Bedbury ,  John P. Cannady ,  Binh T. Nguyen

发明人： Curtis J. Bedbury ,  John P. Cannady ,  Binh T. Nguyen

IPC分类号： C07F708

CPC分类号： C07F3/02 ,  C07F7/122

摘要： Processes for the preparation of phenyl Grignard reagents in co-solvents of toluene and ether and, the preparation of phenylchlorosilane intermediates using co-solvents of toluene and ether essentially in a one step process. The phenylchlorosilanes in the processes of this invention are important intermediates for the preparation of various silicone materials.

摘要翻译： 在甲苯和乙醚的共溶剂中制备苯基格氏试剂的方法，基本上在一步法中使用甲苯和乙醚的共溶剂制备苯基氯硅烷中间体。 本发明方法中的苯基氯硅烷是制备各种有机硅材料的重要中间体。

公开(公告)号：US06518447B2

公开(公告)日：2003-02-11

申请号：US09985528

申请日：2001-11-05

申请人： Yoichi Tonomura ,  Tohru Kubota ,  Yasufumi Kubota

发明人： Yoichi Tonomura ,  Tohru Kubota ,  Yasufumi Kubota

IPC分类号： C07F708

CPC分类号： C07F7/12 ,  C07F7/188

摘要： Chlorosilane compounds having a thexyl group which is a bulky substituent group are novel. The compounds are useful silylating agents because stable silylated products are obtained due to the bulky substituent group.

公开(公告)号：US06495622B1

公开(公告)日：2002-12-17

申请号：US09722975

申请日：2000-11-27

申请人： David George Leppard ,  Vien Van Toan ,  Roland A. E. Winter ,  Michela Bonora

发明人： David George Leppard ,  Vien Van Toan ,  Roland A. E. Winter ,  Michela Bonora

IPC分类号： C07F708

CPC分类号： C07C45/71 ,  C07C49/84 ,  C08K5/132 ,  C08L23/16 ,  C08L2205/02 ,  C08L23/00 ,  C08L2666/06 ,  C08L23/02

摘要： Compositions comprising A) a polyolefin or polyolefin copolymer, and B) a compound of the formula I wherein R1 is O or O—X—O; R2, R3, R4 and R5 independently are hydrogen, halogen, C1-C8alkyl, C1-C8alkoxy, SR10, SO2R10, phenyl, CF3, COOR11; and wherein R2 and R3 also may be OH; R6 and R7 are H or C1-C8alkyl; R8 and R9 are H, C1-C8alkyl or allyl; R10 is phenyl or C1-C12alkyl; R11 is C1-C8alkyl; C3-C50alkylene interrupted by one or more O; cyclohexyl; benzyl; allyl; X is C2-C18alkylene; C3-C12hydroxyalkylene; or a group selected from those of the formulae where D and D′ independently are a direct bond or C1-C3alkylene; and Y is O, S, SO2, or C1-C3alkylene, e.g. polyethylene films, are well stabilized against the effects of light, oxygen and heat. Some novel compounds of component B are valuable stabilizers for organic material against damage by light, oxygen and/or heat.

摘要翻译： 包含A）聚烯烃或聚烯烃共聚物的组合物，和B）其中R1为O或OXO的式I化合物; R2，R3，R4和R5独立地为氢，卤素，C1-C8烷基，C1-C8烷氧基，SR10，SO2R10，苯基，CF3 ，COOR11; 并且其中R2和R3也可以是OH; R6和R7是H或C1-C8烷基; R8和R9是H，C1-C8烷基或烯丙基; R10是苯基或C1-C12烷基; R11是C1-C8烷基; C3-C50亚烷基被一个或多个O中断; 环己基 苄基; 烯丙基; X是C 2 -C 18亚烷基; C3-C12羟基亚烷基; 或选自式D和D'的基团的基团独立地为直接键或C 1 -C 3亚烷基; 并且Y是O，S，SO 2或C 1 -C 3亚烷基。 聚乙烯薄膜对光，氧和热的影响是很好的稳定的。 组分B的一些新型化合物是有机材料对光，氧和/或热的损害的有价值的稳定剂。

公开(公告)号：US06472549B1

公开(公告)日：2002-10-29

申请号：US10060287

申请日：2002-02-01

申请人： Christoph Batz-Sohn ,  Peter Panster ,  Rudolf Michel ,  Michael Albert ,  Ivo Vryens

发明人： Christoph Batz-Sohn ,  Peter Panster ,  Rudolf Michel ,  Michael Albert ,  Ivo Vryens

IPC分类号： C07F708

CPC分类号： C07F7/0829 ,  C07F7/14

摘要： Propyl silanes functionalized in 3-position are produced by catalytically reacting allyl compounds of the formula H2C═CH—CH2X with silanes of the formula R2R3R4SiH and using a 3- to 100-fold excess of silane.

摘要翻译： 通过将式H2C = CH-CH2X的烯丙基化合物与式R2R3R4SiH的硅烷催化反应并使用3至100倍过量的硅烷来制备3-位官能化的丙基硅烷。

公开(公告)号：US06457303B1

公开(公告)日：2002-10-01

申请号：US09798196

申请日：2001-03-02

申请人： Gunda I Georg ,  Sajiv K. Nair ,  Emily Reiff ,  Ashok Rao Tunoori ,  John T. Henri

发明人： Gunda I Georg ,  Sajiv K. Nair ,  Emily Reiff ,  Ashok Rao Tunoori ,  John T. Henri

IPC分类号： C07F708

CPC分类号： C07D417/06 ,  C07B2200/07 ,  C07C45/29 ,  C07C67/31 ,  C07D277/24 ,  C07D493/04 ,  C07F7/1892 ,  C07C47/21 ,  C07C69/734

摘要： Various epothilone precursors needed for the preparation of final epothilones are provided.

摘要翻译： 提供了制备最终埃坡霉素所需的各种埃坡霉素前体

公开(公告)号：US06455721B1

公开(公告)日：2002-09-24

申请号：US09951219

申请日：2001-09-14

申请人： Florian Johannes Schattenmann

发明人： Florian Johannes Schattenmann

IPC分类号： C07F708

CPC分类号： C07F7/1876

摘要： A method for the preparation of organyltriorganooxysilanes containing at least one silicon-carbon bond is provided comprising reacting at least one tetraorganooxysilane with an activated carbon and at least one base.

摘要翻译： 提供一种制备含有至少一个硅 - 碳键的有机三氧化硅烷的方法，包括使至少一种四有机氧基硅烷与活性炭和至少一个碱反应。

公开(公告)号：US06455699B1

公开(公告)日：2002-09-24

申请号：US09633561

申请日：2000-08-07

申请人： Dennis P. Curran ,  Hubert Josien ,  Bom David

发明人： Dennis P. Curran ,  Hubert Josien ,  Bom David

IPC分类号： C07F708

CPC分类号： C07D471/14 ,  A61K31/437 ,  C07F7/0812 ,  C07F7/0814 ,  C07F7/083

摘要： The present invention provides generally a compound having the following general formula (1): wherein R1 and R2 are independently the same or different and are hydrogen, an alkyl group, an alkenyl group, a benzyl group, an alkynyl group, an alkoxyl group, an aryloxy group, an acyloxy group, —OC(O)ORd, wherein Rd is an alkyl group, a carbamoyloxy group, a halogen, a hydroxyl group, a nitro group, a cyano group, an azido group, a formyl group, a hydrazino group, an acyl group, an amino group, —SRc, wherein, Rc is hydrogen, an acyl group, an alkyl group, or an aryl group, or R1 and R2 together form a group of the formula —O(CH2)nO— wherein n represents the integer 1 or 2; R3 is H, F, a halogen atom, a nitro group, an amino group, a hydroxyl group, or a cyano group; or R2 and R3 together form a group of the formula —O(CH2)nO— wherein n represents the integer 1 or 2; R4 is H, F, a C1-3 alkyl group, a C2-3 alkenyl group, a C2-3 alkynyl group, or a C1-3 alkoxyl group; R5 is a C1-10 alkyl group, or a propargyl group; and R6, R7 and R8 are independently a C1-10 alkyl group, a C2-10 alkenyl group, a C2-10 alkynyl group, an aryl group or a —(CH2)NR9 group, wherein N is an integer within the range of 1 through 10 and R9 is a hydroxyl group, alkoxy group, an amino group, an alkylamino group, a dialkylamino group, a halogen atom, a cyano group or a nitro group; and pharmaceutically acceptable salts thereof.

摘要翻译： 本发明通常提供具有以下通式（1）的化合物：其中R 1和R 2独立地相同或不同，为氢，烷基，烯基，苄基，炔基，烷氧基， 芳氧基，酰氧基，-OC（O）ORd，其中Rd为烷基，氨基甲酰氧基，卤素，羟基，硝基，氰基，叠氮基，甲酰基， 肼基，酰基，氨基，-SRc，其中Rc是氢，酰基，烷基或芳基，或者R1和R2一起形成式-O（CH 2）n O的基团 - 其中n表示整数1或2; R3是H，F，卤素原子，硝基，氨基，羟基或氰基; 或R 2和R 3一起形成式-O（CH 2）n O-的基团，其中n表示整数1或2; R4是H，F，C1-3烷基，C2-3烯基，C2-3炔基或C1-3烷氧基; R5是C1-10烷基或炔丙基; 并且R 6，R 7和R 8独立地为C 1-10烷基，C 2-10烯基，C 2-10炔基，芳基或 - （CH 2）NR 9基，其中N是在 1〜10，R9为羟基，烷氧基，氨基，烷基氨基，二烷基氨基，卤素原子，氰基或硝基; 和其药学上可接受的盐。

公开(公告)号：US06426428B2

公开(公告)日：2002-07-30

申请号：US09332200

申请日：1999-06-14

申请人： Serge Forestier ,  Hervé Richard ,  Delphine Allard ,  Didier Candau

发明人： Serge Forestier ,  Hervé Richard ,  Delphine Allard ,  Didier Candau

IPC分类号： C07F708

CPC分类号： A61Q17/04 ,  A61K8/35 ,  A61K8/585 ,  A61K2800/52

摘要： Topically applicable, stable, UV-photoprotective cosmetic/dermatological compositions well suited for the photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, comprise (a) an effective UV-photoprotecting amount of at least one dibenzoylmethane UV-sunscreen compound and (b) an effective dibenzoylmethane compound (a) photostabilizing amount of at least one benzalmalonate silane having the structural formula (I):

摘要翻译： 适用于UV-A和UV-B照射的破坏性影响的适合于对人体皮肤和/或头发进行光保护的非常适合于保护皮肤和/或头发的局部适用的稳定的UV-光保护性化妆品/皮肤病学组合物包括（a）有效的UV-光保护剂量 至少一种二苯甲酰甲烷紫外线防晒化合物和（b）有效的二苯甲酰甲烷化合物（a）光稳定化量的至少一种具有结构式（I）的苯甲醛丙二酸酯硅烷：