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公开(公告)号:US20080241190A1
公开(公告)日:2008-10-02
申请号:US11937657
申请日:2007-11-09
申请人: Jeremy Kroll , Axel Neubauer , Philip Utley , Michael Roof , Juergen Daemmgen , Knut Elbers
发明人: Jeremy Kroll , Axel Neubauer , Philip Utley , Michael Roof , Juergen Daemmgen , Knut Elbers
CPC分类号: A61K39/105 , A61K2039/522 , A61K2039/542 , A61K2039/543 , A61K2039/545 , A61K2039/552
摘要: The present invention is broadly concerned with vaccination of horses against proliferative enteritis, preferably equine proliferative ileitis, which is caused by an obligate intracellular bacterium Lawsonia Intracellularis (L. intracellularis). Specifically, the invention provides for a method of providing immune protection against L. intracellularis by vaccinating horses, preferably foals starting from one (1) week of age. Preferably the foals are vaccinated with about 4.9 log 10 to about 6.9 log 10 of a live modified L. intracellularis bacteria per dose.
摘要翻译: 本发明广泛涉及针对增殖性肠炎(优选为马氏增生性回肠炎)的马的免疫接种,其是由专性细胞内细菌细胞内劳森氏细菌(细胞内胞内)引起的。 具体地,本发明提供了一种通过接种马,优选从一(1)周龄开始的驹提供针对细胞内毒素L.的免疫保护的方法。 优选地,以每剂量约4.9log 10至约6.9log 10的活修饰的细胞内源细菌细菌接种驹。
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公开(公告)号:US09534207B2
公开(公告)日:2017-01-03
申请号:US14281287
申请日:2014-05-19
申请人: Kim Burgard , Jeremy Kroll , Sarah M. Layton , Volker Ohlinger , Francois-Xavier Orveillon , Stefan Pesch , Michael Dennis Piontkowski , Michael B. Roof , Philip Utley , Eric Martin Vaughn
发明人: Kim Burgard , Jeremy Kroll , Sarah M. Layton , Volker Ohlinger , Francois-Xavier Orveillon , Stefan Pesch , Michael Dennis Piontkowski , Michael B. Roof , Philip Utley , Eric Martin Vaughn
IPC分类号: A61K39/225 , C12N7/00 , A61K39/12 , A61K38/00 , A61K39/00
CPC分类号: A61K39/12 , A61K2039/5254 , A61K2039/53 , A61K2039/552 , A61K2039/575 , C12N7/00 , C12N2770/10021 , C12N2770/10034 , C12N2770/10064 , C12N2770/10071
摘要: The present invention is related to improved modified live PRRS vaccines containing new PRRSV European strains of PRRSV and methods of use and manufacture of such vaccines.
摘要翻译: 本发明涉及包含新的PRRSV欧洲PRRSV菌株的改良的活的PRRS疫苗,以及使用和制造这种疫苗的方法。
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公开(公告)号:US20110123570A1
公开(公告)日:2011-05-26
申请号:US12942579
申请日:2010-11-09
申请人: Jeremy KROLL , Philip UTLEY , Dianna M. JORDAN
发明人: Jeremy KROLL , Philip UTLEY , Dianna M. JORDAN
CPC分类号: G01N33/56911 , A61K39/102 , A61K2039/552
摘要: The invention provides immunogenic compositions useful for inhibiting, treating, protecting, or preventing infection by Actinobacillus suis. These immunogenic compositions are demonstrated to usefully stimulate immunogenic responses in treated pigs. Some vaccines stimulated reactions sufficient to be protective against A. suis. In addition, the invention provides kits comprising the immunogenic compositions; as well as, methods of using the compositions and kits.
摘要翻译: 本发明提供了可用于抑制,治疗,保护或预防由放线杆菌感染的免疫原性组合物。 证明这些免疫原性组合物有效刺激处理的猪的免疫原性反应。 一些疫苗刺激的反应足以防止A. suis。 此外,本发明提供了包含免疫原性组合物的试剂盒; 以及使用组合物和试剂盒的方法。
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公开(公告)号:US08563005B2
公开(公告)日:2013-10-22
申请号:US12942579
申请日:2010-11-09
申请人: Jeremy Kroll , Philip Utley , Dianna Murphy Jordan
发明人: Jeremy Kroll , Philip Utley , Dianna Murphy Jordan
CPC分类号: G01N33/56911 , A61K39/102 , A61K2039/552
摘要: The invention provides immunogenic compositions useful for inhibiting, treating, protecting, or preventing infection by Actinobacillus suis. These immunogenic compositions are demonstrated to usefully stimulate immunogenic responses in treated pigs. Some vaccines stimulated reactions sufficient to be protective against A. suis. In addition, the invention provides kits comprising the immunogenic compositions; as well as, methods of using the compositions and kits.
摘要翻译: 本发明提供了可用于抑制,治疗,保护或预防由放线杆菌感染的免疫原性组合物。 证明这些免疫原性组合物有效刺激处理的猪的免疫原性反应。 一些疫苗刺激的反应足以防止A. suis。 此外,本发明提供了包含免疫原性组合物的试剂盒; 以及使用组合物和试剂盒的方法。
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公开(公告)号:US20120213810A1
公开(公告)日:2012-08-23
申请号:US13396298
申请日:2012-02-14
申请人: Kim BURGARD , Jeremy KROLL , Sarah M. LAYTON , Volker OHLINGER , Francois-Xavier ORVEILLON , Stefan PESCH , Michael Dennis PIONTKOWSKI , Michael B. ROOF , Philip UTLEY , Eric Martin VAUGHN
发明人: Kim BURGARD , Jeremy KROLL , Sarah M. LAYTON , Volker OHLINGER , Francois-Xavier ORVEILLON , Stefan PESCH , Michael Dennis PIONTKOWSKI , Michael B. ROOF , Philip UTLEY , Eric Martin VAUGHN
CPC分类号: A61K39/12 , A61K2039/5254 , A61K2039/53 , A61K2039/552 , A61K2039/575 , C12N7/00 , C12N2770/10021 , C12N2770/10034 , C12N2770/10064 , C12N2770/10071
摘要: The present invention is related to improved modified live PRRS vaccines containing new PRRSV European strains of PRRSV and methods of use and manufacture of such vaccines.
摘要翻译: 本发明涉及包含新的PRRSV欧洲PRRSV菌株的改良的活的PRRS疫苗,以及使用和制造这种疫苗的方法。
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公开(公告)号:US20140255442A1
公开(公告)日:2014-09-11
申请号:US14281287
申请日:2014-05-19
申请人: Kim BURGARD , Jeremy KROLL , Sarah M. LAYTON , Volker OHLINGER , Francois-Xavier ORVEILLON , Stefan PESCH , Michael Dennis PIONTKOWSKI , Michael B. ROOF , Philip UTLEY , Eric Martin VAUGHN
发明人: Kim BURGARD , Jeremy KROLL , Sarah M. LAYTON , Volker OHLINGER , Francois-Xavier ORVEILLON , Stefan PESCH , Michael Dennis PIONTKOWSKI , Michael B. ROOF , Philip UTLEY , Eric Martin VAUGHN
IPC分类号: C12N7/00
CPC分类号: A61K39/12 , A61K2039/5254 , A61K2039/53 , A61K2039/552 , A61K2039/575 , C12N7/00 , C12N2770/10021 , C12N2770/10034 , C12N2770/10064 , C12N2770/10071
摘要: The present invention is related to improved modified live PRRS vaccines containing new PRRSV European strains of PRRSV and methods of use and manufacture of such vaccines.
摘要翻译: 本发明涉及包含新的PRRSV欧洲PRRSV菌株的改良的活的PRRS疫苗,以及使用和制造这种疫苗的方法。
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公开(公告)号:US08765142B2
公开(公告)日:2014-07-01
申请号:US13396298
申请日:2012-02-14
申请人: Kim Burgard , Jeremy Kroll , Sarah M. Layton , Volker Ohlinger , Francois-Xavier Orveillon , Stefan Pesch , Michael Dennis Piontkowski , Michael B. Roof , Philip Utley , Eric Martin Vaughn
发明人: Kim Burgard , Jeremy Kroll , Sarah M. Layton , Volker Ohlinger , Francois-Xavier Orveillon , Stefan Pesch , Michael Dennis Piontkowski , Michael B. Roof , Philip Utley , Eric Martin Vaughn
IPC分类号: A61K39/225 , A61K38/00
CPC分类号: A61K39/12 , A61K2039/5254 , A61K2039/53 , A61K2039/552 , A61K2039/575 , C12N7/00 , C12N2770/10021 , C12N2770/10034 , C12N2770/10064 , C12N2770/10071
摘要: The present invention is related to improved modified live PRRS vaccines containing new PRRSV European strains of PRRSV and methods of use and manufacture of such vaccines.
摘要翻译: 本发明涉及包含新的PRRSV欧洲PRRSV菌株的改良的活的PRRS疫苗,以及使用和制造这种疫苗的方法。
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