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公开(公告)号:US20120135031A1
公开(公告)日:2012-05-31
申请号:US13169159
申请日:2011-06-27
IPC分类号: A61K31/7088 , A61P31/04 , A61P33/00 , A61P37/04
摘要: A method of enhancing an immune response to an antigen is provided. The method involves augmenting the level of a TAP molecule in a target cell bearing the antigen. Preferably, the TAP molecules enhanced by administering a nucleic acid sequence encoding a TAP-1 and/or TAP-2 molecule. The method is useful in treating infectious diseases and cancer.
摘要翻译: 提供了增强对抗原的免疫应答的方法。 该方法涉及增加携带抗原的靶细胞中TAP分子的水平。 优选地,通过施用编码TAP-1和/或TAP-2分子的核酸序列来增强TAP分子。 该方法可用于治疗感染性疾病和癌症。
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公开(公告)号:US20100080776A1
公开(公告)日:2010-04-01
申请号:US12029080
申请日:2008-02-11
IPC分类号: A61K35/76 , A61K31/7052 , A61P37/04
摘要: A method of enhancing an immune response to an antigen is provided. The method involves augmenting the level of a TAP molecule in a target cell bearing the antigen. Preferably, the TAP molecules enhanced by administering a nucleic acid sequence encoding a TAP-1 and/or TAP-2 molecule. The method is useful in treating infectious diseases and cancer.
摘要翻译: 提供了增强对抗原的免疫应答的方法。 该方法涉及增加携带抗原的靶细胞中TAP分子的水平。 优选地,通过施用编码TAP-1和/或TAP-2分子的核酸序列来增强TAP分子。 该方法可用于治疗感染性疾病和癌症。
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公开(公告)号:US07378087B2
公开(公告)日:2008-05-27
申请号:US10046542
申请日:2002-01-16
摘要: A method of enhancing an immune response to an antigen is provided. The method involves augmenting the level of a TAP molecule in a target cell bearing the antigen. Preferably, the TAP molecules enhanced by administering a nucleic acid sequence encoding a TAP-1 and/or TAP-2 molecule. The method is useful in treating infectious diseases and cancer.
摘要翻译: 提供了增强对抗原的免疫应答的方法。 该方法涉及增加携带抗原的靶细胞中TAP分子的水平。 优选地,通过施用编码TAP-1和/或TAP-2分子的核酸序列来增强TAP分子。 该方法可用于治疗感染性疾病和癌症。
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公开(公告)号:US07994146B2
公开(公告)日:2011-08-09
申请号:US12029080
申请日:2008-02-11
摘要: A method of enhancing an immune response to an antigen is provided. The method involves augmenting the level of a TAP molecule in a target cell bearing the antigen. Preferably, the TAP molecules enhanced by administering a nucleic acid sequence encoding a TAP-1 and/or TAP-2 molecule. The method is useful in treating infectious diseases and cancer.
摘要翻译: 提供了增强对抗原的免疫应答的方法。 该方法涉及增加携带抗原的靶细胞中TAP分子的水平。 优选地,通过施用编码TAP-1和/或TAP-2分子的核酸序列来增强TAP分子。 该方法可用于治疗感染性疾病和癌症。
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