Abstract:
The present invention relates to Angiopoietin-3 (Ang-3) and Angiopoietin-4 (Ang-4). The present invention also relates to methods of modulating an activity of Ang-3 or Ang-4. The present invention further relates to methods of treating cancer, diabetes, and arthritis.
Abstract:
Disclosed is a method, system, and program product for providing an efficient mechanism to provide updateable relational views over XML. This will allow application developers to write both queries and updates using a relational (SQL) syntax, even though the underlying data is stored as XML. According to some approaches, this is accomplished by implementing a reverse mapping from the data within the views to the node addresses of the corresponding data in the underlying XML document.
Abstract:
Methods and apparatus for enabling a plurality of table columns arranged to be associated with large objects (LOBs) to share a single LOB data segment within a database are disclosed. According to one aspect of the present invention, a method for allocating space associated with at least a first column arranged to accommodate LOB data and a second column arranged to accommodate LOB data includes allocating a first LOB data segment. The method also includes associating both the first column and the second column with the first LOB data segment.
Abstract:
The present invention relates to Ang-1, Ang-2, and Ang-3, and to methods and uses of the same. The present invention also relates to ECM-binding fragments, non-ECM-binding fragments, proteolytic resistant fragments and C-terminal fragments of Ang-1, and to methods and uses of the same.
Abstract:
Methods and apparatus for enabling a plurality of table columns arranged to be associated with large objects (LOBs) to share a single LOB data segment within a database are disclosed. According to one aspect of the present invention, a method for allocating space associated with at least a first column arranged to accommodate LOB data and a second column arranged to accommodate LOB data includes allocating a first LOB data segment. The method also includes associating both the first column and the second column with the first LOB data segment.
Abstract:
Methods and apparatus for efficiently storing data in a variable array (VARRAY) of a database system are disclosed. A method for storing data in a VARRAY having an associated large object segment in a system having a memory and a kernel includes determining a size of data to be inserted into the VARRAY. The method also includes determining when the size of the data is less than a threshold value, and storing the data as inline raw data in a column of the VARRAY that is present in the memory when the size of the data is less than the threshold value. When the size of the data is not less than the threshold value, the data is stored in a large object that is associated with the VARRAY. Further, when a VARRAY type is evolved to have a larger maximum size, existing data is not migrated or transformed.
Abstract:
A communication device with a short message filter mechanism. The communication device comprises an incoming phone number filter module for acquiring the number of digits in an incoming phone number accompanying a short message received by the communication device and, if the number of digits in the incoming phone number is less than a preset value, deleting the short message, and a keyword filter module for determining whether the short message contains a specific keyword and, if so, deleting the short message.
Abstract:
A request to execute a query is received in a database system. In response, the database system determines that a collection of data elements to be returned by the query corresponds to a first data structure not defined within a type dictionary of the database system. The database system obtains attribute values that describe respective data fields within the first data structure, and records, within the type dictionary, a first data type definition that specifies the data fields described by the attribute values.
Abstract:
The present invention relates to Angiopoietin-3 (Ang-3) and Angiopoietin-4 (Ang-4). The present invention also relates to methods of modulating an activity of Ang-3 or Ang-4. The present invention further relates to methods of treating cancer, diabetes, and arthritis.
Abstract:
Pharmaceutical compositions that comprise a pharmaceutically acceptable carrier and either a therapeutically effective amount of an ECM-binding fragment of Ang-1 protein that comprises SEQ ID NO:1 and/or SEQ ID NO:2 or a homologous peptide thereof and pharmaceutical compositions that comprise a pharmaceutically acceptable carrier and a vector comprising a nucleic acid molecule that comprises the nucleotide sequence that encodes an ECM-binding fragment of Ang-1 protein that comprises SEQ ID NO:1 and/or SEQ ID NO:2 or a homologous peptide thereof are disclosed. Methods of using such compositions to treat individuals suspected of having coronary artery disease, vascular disease or a condition involving ischemia and to promote angiogenesis, endothelial survival and maintaining vascular integrity are disclosed. Methods to identify compounds that modulates binding of Ang-1 to ECM are disclosed. Pharmaceutical compositions which comprise a therapeutically effective amount of Ang-2 protein and/or a vector comprising a nucleic acid molecule that comprises the nucleotide coding sequence of Ang-2 and methods of using such compositions to treat individuals suspected of having cancer are disclosed.
Abstract translation:包含药学上可接受的载体和治疗有效量的包含SEQ ID NO:1和/或SEQ ID NO:2的Ang-1蛋白的ECM结合片段或其同源肽的药物组合物和包含 药学上可接受的载体和载体,其包含核酸分子,其包含编码包含SEQ ID NO:1和/或SEQ ID NO:2或其同源肽的Ang-1蛋白的ECM结合片段的核苷酸序列 披露 公开了使用这些组合物治疗怀疑有冠状动脉疾病,血管疾病或涉及缺血的病症并促进血管发生,内皮存活和维持血管完整性的方法。 公开了鉴定调节Ang-1与ECM结合的化合物的方法。 公开了包含治疗有效量的Ang-2蛋白和/或包含含有Ang-2的核苷酸编码序列的核酸分子的载体的药物组合物和使用该组合物治疗疑似患有癌症的个体的方法。