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公开(公告)号:US12161454B2
公开(公告)日:2024-12-10
申请号:US17430735
申请日:2020-03-13
Inventor: Volkmar Schulz , Sebastian Reinartz , Dennis Pantke , Florian Mueller
IPC: G01N27/84 , A61B5/0515 , G01R33/12
Abstract: The invention relates to a method for carrying out signal detection by means of magnetic particle imaging, in which method magnetic/magnetisable particles (4), arranged in the field-free region of a location-dependent magnetic field, in particular a gradient magnetic field, are magnetised by means of an excitation magnetic field that changes over time, and the harmonics (9, 15), generated by the particles (4), of the frequency of the excitation magnetic field are detected as a signal from the magnetic particles (4) by means of a receiver coil arrangement (1) which in particular surrounds the particles (4), wherein a signal-transmitting arrangement, which has an outer coil (10) and at least one inner coil (11; 16, 17) connected in series to said outer coil, is positioned within the receiver coil arrangement (1) around the particles (4), wherein the signal received from the particles (4) by the at least one inner coil (11; 16, 17) is transmitted to the outer coil (10) by current flow and is re-emitted by said outer coil, in particular as a result of which the signal (S) received directly from the particles (4) and the signal (S) received from the particles (4) indirectly by the outer coil (10) are superimposed at the receiver coil arrangement (1). The invention also relates to a signal-transmitting arrangement for a magnetic-particle-imaging scanner/spectrometer, comprising an outer coil (10) which in particular has a smaller diameter than the sample-receiving channel (2) of the scanner/spectrometer, and comprising at least one inner coil (11; 16, 17) which is arranged in the outer coil (10), preferably arranged coaxially therein, and in particular has greater diameter than a sample to be examined, wherein the outer coil (10) and the inner coil (11; 16, 17) are electrically connected in series. The invention also relates to a system comprising a magnetic-particle-imaging scanner and a signal-transmitting arrangement.
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2.
公开(公告)号:US20240186996A1
公开(公告)日:2024-06-06
申请号:US18552157
申请日:2022-03-21
Inventor: Lukas HÜSSEN , Muh-Dey WEI , Renato NEGRA
IPC: H03K17/16
CPC classification number: H03K17/162 , H03K2217/0063 , H03K2217/0072 , H03K2217/0081
Abstract: The invention relates to an insulated gate driver circuit for driving a gate terminal of a semiconductor circuit device, including a low voltage part and a high voltage part which are galvanically separated from each other by an insulated coupling section, and the low voltage part is adapted to transmit a signal to the high voltage part comprising an output stage adapted to drive the gate terminal of the semiconductor circuit device in dependence on a switching signal underlying the signal, wherein the insulated gate driver circuit is adapted to provide a power supply to the output stage and an input signal to the output stage based on the signal transmitted via the insulated coupling section.
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公开(公告)号:US11845376B2
公开(公告)日:2023-12-19
申请号:US17285951
申请日:2019-10-16
Applicant: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. , Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen
Inventor: Manuela Junghähnel , Thomas Preussner , Sebastian Winkler , Sofian Hamid , Korbinian Schraml , Jörg Pamp , Dirk Heberling , Christian Hördemann , Ludwig Pongratz , Patrick Gretzki , Arnold Gillner
CPC classification number: B60Q1/0023 , B60Q1/04 , G01S7/03 , G01S13/931 , H01Q1/3233 , H01Q1/3291 , H01Q19/10 , G01S2013/93277
Abstract: Provided is a radar and light emission assembly for emitting light and radar radiation and for detecting at least reflected radar radiation including: a headlight including a light-transparent headlight cover, and a light source, and a light reflector; a radar module, which is arranged behind the headlight cover, integrated in the headlight and including a radar antenna unit. The radar and light emission assembly has at least one radar radiation-forming mechanism, in particular a frequency-selective radar radiation-forming mechanism, including a radar radiation-forming mechanism, which is integrated in the headlight cover. The application of the radar technology, integrated in the headlight, can be further optimized hereby. The invention further relates to a method and a use for a radar and light emission assembly of this type.
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4.
公开(公告)号:US20230311635A1
公开(公告)日:2023-10-05
申请号:US18010409
申请日:2021-06-17
Inventor: Peter Janssen , Jakob Andert , Michael Engels
CPC classification number: B62M23/02 , B62M11/14 , F02N11/04 , F02D9/08 , B62J43/16 , F16H3/72 , F16H2200/2005
Abstract: Disclosed is parallel hybrid drive for a motor vehicle, a motor vehicle, a method for operating a parallel hybrid drive in an all-electric mode, a method for operating a parallel hybrid drive in a direct drive mode, and a method for operating a parallel hybrid drive in a CVT mode. The drive for a motor vehicle includes an electric machine operable as a motor and generator, an internal combustion engine, a drive axle, and an epicyclic gear. The epicyclic gear includes: a first shaft connected to the electric machine; a second shaft connected to the internal combustion engine; and a third shaft connected to the drive axle. A clutch element is configured to firmly connect at least two shafts of the epicyclic gear to each other. A first brake element is configured to prevent rotation of the internal combustion engine in one direction of rotation.
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公开(公告)号:US20220365083A1
公开(公告)日:2022-11-17
申请号:US17767014
申请日:2020-10-07
Inventor: Ute RAFFETSEDER , Daniel BREITKOPF , Thomas RAUEN , Vera JANKOWSKI , Jürgen FLOEGE , Tammo OSTENDORF
IPC: G01N33/564
Abstract: The present invention relates to a method for diagnosing lupus nephritis in an individual suffering from systemic lupus erythematosus (SLE), said method conducted in vitro comprising identifying a protein that comprises an YB-1-like cold-shock domain which bears one or more guanidinylated lysinyl moieties (YB-1-G) in a sample S obtained from the individual. Furthermore, the present invention also refers to treating or preventing lupus nephritis in an individual, wherein lupus nephritis has been diagnosed in the individual by means of a method of the present invention.
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公开(公告)号:US20220316112A1
公开(公告)日:2022-10-06
申请号:US17609360
申请日:2020-05-05
Inventor: Valentine GESCHÉ , Alexander LÖWEN , Kathrin KURTENBACH , Thomas GRIES
Abstract: The invention relates to a method for producing a vascular implant. The method comprises: obtaining vessel parameters; creating a computer-aided model of a vascular implant based on the obtained vessel parameters, wherein the vascular implant comprises one or more modules, each comprising at least one tubular liner body; selecting one or more structural elements of a respective module from the group consisting of: one or more diameter changes along at least one tubular liner body, one or more bifurcations, one or more branches, one or more recesses, one or more local reinforcements, and one or more iliac vessel grafts. The method further comprises: determining parameters relating to the one or more selected structural elements; integrating the structural elements into the computer-aided model according to the determined parameters; and producing the vascular implant based on the created computer-aided model. Furthermore, the invention relates to vascular implants produced by means of the method.
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公开(公告)号:US20220166696A1
公开(公告)日:2022-05-26
申请号:US17440892
申请日:2020-03-20
Inventor: Abhinav SADU , Gianluca LIPARI , Ferdinanda PONCI , Jindal AKSHAY
IPC: H04L43/0817 , H04L67/12 , H04L9/40
Abstract: Devices and method are disclosed for a load allocation and monitoring for a resource to be allocated in a network, where the resource to be allocated is a critical resource in terms of supply security for a population group and/or a system, and the critical resource comprises electric power, where the network is subdivided into network units, and each network unit has a network unit controller. In some examples, the method includes storing network unit control methods, network unit parameter data sets, and subnetwork monitoring methods in at least one blockchain; allocating a subnetwork monitoring unit to one part of the network; and transmitting a network unit control method and a network unit parameter data set to each network unit controller of the part of the network, and the transmitting of the network unit control methods and the network unit parameter data sets is cryptographically secured against reading and tampering with the network unit control methods and the network unit parameter data sets in such a manner that the corresponding reading and tampering are precluded to the greatest extent possible and occurs in such a manner that the proper functioning of each network unit controller of the part of the network is ensured; and monitoring the proper function of each network unit controller of the part of the network by means of the subnetwork monitoring unit using a corresponding subnetwork monitoring method.
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公开(公告)号:US20210387563A1
公开(公告)日:2021-12-16
申请号:US17285951
申请日:2019-10-16
Applicant: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. , Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen
Inventor: Manuela Junghähnel , Thomas Preussner , Sebastian Winkler , Sofian Hamid , Korbinian Schraml , Jörg Pamp , Dirk Heberling , Christian Hördemann , Ludwig Pongratz , Patrick Gretzki , Arnold Gillner
Abstract: Provided is a radar and light emission assembly for emitting light and radar radiation and for detecting at least reflected radar radiation including: a headlight including a light-transparent headlight cover, and a light source, and a light reflector; a radar module, which is arranged behind the headlight cover, integrated in the headlight and including a radar antenna unit. The radar and light emission assembly has at least one radar radiation-forming mechanism, in particular a frequency-selective radar radiation-forming mechanism, including a radar radiation-forming mechanism, which is integrated in the headlight cover. The application of the radar technology, integrated in the headlight, can be further optimized hereby. The invention further relates to a method and a use for a radar and light emission assembly of this type.
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公开(公告)号:US20210213096A1
公开(公告)日:2021-07-15
申请号:US15999531
申请日:2017-02-16
Applicant: FORSCHUNGSZENTRUM BORSTEL LEIBNIZ-ZENTRUM FUR MEDIZIN UND BIOWSSENSCHAFTEN , FREIE UNIVERSITAT BERLIN , UNIVERSITAT ZU LUBECK , RHEINISCH-WESTFALISCHE TECHNISCHE HOCHSCHULE (RWTH) AACHEN
Inventor: Klaus BRANDENBURG , Lena HEINBOCKEL , Norbert REILING , Guillermo MARTINEZ DE TEJADA , Tobias SCHURHOLZ , Karl MAUSS , Gunther WEINDL
IPC: A61K38/16 , C07K7/08 , A61K38/10 , A61K31/43 , A61K31/7048 , A61K38/14 , A61K31/7036 , A61K31/496 , A61K31/431 , A61K31/65 , A61K31/546 , A01N63/50 , A01N43/90 , A01N43/16 , A01N37/18 , A61P31/06 , A61P17/02 , A61P31/04
Abstract: The present invention relates to a pharmaceutical composition comprising or consisting of a combination of (a) two or more peptides, each peptide consisting of or comprising 17 to 23 amino acids, wherein the amino acids in positions 1 to 23, counted from the N-terminus, are as follows (1) G, S or lacking; (2) C or lacking; (3) K or R; (4) K or R; (5) Y, W or F; (6) K or R; (7) K or R; (8) F, W or L; (9) K or R; (10) K or L or lacking; (11) W, L or F; (12) K or R; (13) F, Y or C; (14) K or R; (15) G or Q; (16) K or R; (17) F, L or W; (18) F or W; (19) F, L or W; (20) W or F; (21) C or lacking; (22) F or G or lacking; (23) G or lacking; or (b) one or more peptides, each peptide consisting of or comprising 17 to 23 amino acids, wherein the amino acids in positions 1 to 23, counted from the N-terminus, are as follows (1) G, S or lacking; (2) C or lacking; (3) K or R; (4) K or R; (5) Y, W or F; (6) K or R; (7) K or R; (8) F, W or L; (9) K or R; (10) K or L or lacking; (11) W, L or F; (12) K or R; (13) F, Y or C; (14) K or R; (15) G or Q; (16) K or R; (17) F, L or W; (18) F or W; (19) F, L or W; (20) W or F; (21) C or lacking; (22) F or G or lacking; (23) G or lacking, and one or more antibiotics selected from small organic molecule antibiotics such as ceftriaxone, oxacillin, amoxicillin, amikacin, ciprofloxacin, erythromycin, imipenem and tetracycline, and peptidic antibiotics such as daptomycin and vancomycin.
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公开(公告)号:US20210106745A1
公开(公告)日:2021-04-15
申请号:US16970547
申请日:2019-03-20
Inventor: Ahmed Ali KASHEFI-KHORASANI
Abstract: The invention relates to a degassing devive (25) for degassing blood, comprising a blood chamber (1, 1a, 1b) with a blood inlet (2) and a blood outlet (3), via which blood can be guided/is guided through the blood chamber (1, 1a, 1b), at least one underpressure chamber (11) with an underpressure attachment (8) via which the at least one underpressure chamber (11) is provided with an underpressure, at least one semipermeable membrane (4, 4a), which is arranged between the at least one underpressure chamber (11) and the blood chamber (1), wherein the blood chamber (1) comprises a first and a second sub-chamber (1a, 1b) which are arranged next to each other in a direction perpendicular to the direction of gravity, and a bridging region (9) which connects the two subchambers (1a, 1b) at their upper ends, wherein the blood inlet (2) is arranged in the lower region of the first subchamber (1a), and the blood outlet (3) is arranged in the lower region of the second subchamber (1b). The invention also relates to a system for extracorporeal treatment of blood.
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