公开(公告)号：US20060155178A1

公开(公告)日：2006-07-13

申请号：US11261452

申请日：2005-10-27

Applicant: Vadim Backman ,  Hemant Roy ,  Ramesh Wali ,  Young Kim ,  Yang Liu ,  Guillermo Ameer ,  Jian Yang ,  Antonio Webb ,  Josephine Allen

Inventor： Vadim Backman ,  Hemant Roy ,  Ramesh Wali ,  Young Kim ,  Yang Liu ,  Guillermo Ameer ,  Jian Yang ,  Antonio Webb ,  Josephine Allen

IPC: A61B5/00

CPC classification number: G01N33/48

Abstract: A method of examining a sample includes measuring, as function of wavelength of light elastically scattered from the sample, at least 2 properties, selected from the group consisting of scattering angle theta of the light, scattering angle phi of the light, and polarization of the light. The scattering angle theta is an angle between backward direction and direction of propagation of the light, and scattering angle phi is an angle between incident light polarization and projection of direction of the light propagation onto a plane in which incident electric field oscillates.

Abstract translation: 检查样品的方法包括测量作为从样品弹性散射的光的波长的函数，至少选自由光的散射角度θ，光的散射角度phi和光的偏振度 光。 散射角θ是光的向后方向和传播方向之间的角度，散射角φi是入射光偏振与入射电场振荡的平面上的光传播方向的投影之间的角度。

公开(公告)号：US20070179368A1

公开(公告)日：2007-08-02

申请号：US11604653

申请日：2006-11-27

Applicant: Vadim Backman ,  Hemant Roy ,  Ramesh Wali ,  Young Kim ,  Michael Siegel ,  Vladimir Turzhitsky

Inventor： Vadim Backman ,  Hemant Roy ,  Ramesh Wali ,  Young Kim ,  Michael Siegel ,  Vladimir Turzhitsky

IPC: A61B5/00

CPC classification number: A61B5/0261 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/0091 ,  A61B5/1459

Abstract: The present invention, in one aspect, relates to a method for examining a target for tumors or lesions using what is referred to as “Early Increase in microvascular Blood Supply” (EIBS) that exists in tissues that are close to, but are not themselves, the abnormal tissue and in tissues that precede the development of such lesions or tumors. While the abnormal tissue can be a lesion or tumor, the abnormal tissue can also be tissue that precedes formation of a lesion or tumor, such as a precancerous adenoma, aberrant crypt foci, tissues that precede the development of dysplastic lesions that themselves do not yet exhibit dysplastic phenotype, and tissues in the vicinity of these lesions or pre-dysplastic tissues.

Abstract translation: 本发明在一个方面涉及使用所谓的“微血管供血的早期增加”（EIBS）来检查肿瘤或病变的靶标的方法，所述方法存在于接近但不是本身的组织中 ，异常组织和在这些损伤或肿瘤的发展之前的组织中。 虽然异常组织可以是病变或肿瘤，但是异常组织也可以是在形成病变或肿瘤之前的组织，例如癌前腺瘤，异常隐窝灶，在发育不良的病变之前的组织，其本身还没有 表现出发育不良的表型，以及这些损伤或发育不良前组织附近的组织。