公开(公告)号：US07157049B2

公开(公告)日：2007-01-02

申请号：US10293214

申请日：2002-11-13

申请人： Ramoncito Magpantay Valencia ,  YihFar Chen ,  Susan Newcomb Hurt ,  Joseph Roby Iringan Urcia ,  Gowri Pyapali Selvan

发明人： Ramoncito Magpantay Valencia ,  YihFar Chen ,  Susan Newcomb Hurt ,  Joseph Roby Iringan Urcia ,  Gowri Pyapali Selvan

IPC分类号： G01N15/06 ,  G01N33/00 ,  G01N33/48

CPC分类号： G01N15/1475 ,  B01L3/5027 ,  G01N33/54366 ,  G01N33/80 ,  G01N35/00069 ,  G01N2015/1486

摘要： The present invention is directed to optical bio-discs, methods, and optical disc drives for clinical diagnostics. The present invention is further directed to methods for determining the quantity of a specific type of blood cell in a biological sample including on-disc sample preparation and processing, providing a pre-processed sample onto a capture zone, removing portions of the sample that are not bound in the capture zone, and counting bound cells. Also disclosed are fluidic circuits for processing blood samples for use in a cluster designation marker assay in the optical bio-disc.

摘要翻译： 本发明涉及用于临床诊断的光学生物盘，方法和光盘驱动器。 本发明还涉及用于确定生物样品中特定类型的血细胞数量的方法，包括盘上样品制备和处理，将预处理的样品提供到捕获区上，去除部分样品 不绑定在捕获区域，并计数绑定的细胞。 还公开了用于处理用于光学生物盘中的簇指示标记测定中的血液样品的流体回路。