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公开(公告)号：US20230202966A1
公开(公告)日：2023-06-29
申请号：US17972395
申请日：2022-10-24
Applicant: Renagade Therapeutics Management Inc.
Inventor： Muthusamy Jayaraman , Stephen Scully
IPC: C07C219/06 , C07C219/08 , C07C219/10
CPC classification number: C07C219/06 , C07C219/08 , C07C219/10
Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
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公开(公告)号：US20240141382A1
公开(公告)日：2024-05-02
申请号：US18481393
申请日：2023-10-05
Applicant: ReNAgade Therapeutics Management Inc.
Inventor： Giedrius Gasiunas , Alim Ladha , Vladimir Presnyak , Muthusamy Jayaraman
Abstract: The present disclosure provides methods and compositions comprising novel Cas TypeV programmable nucleases and lipid nanoparticles capable of delivering the Cas TypeV programmable nucleases and genome editing systems comprising same. For therapeutic applications, as well as plants and industrial biotechnology.
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公开(公告)号：US11773061B2
公开(公告)日：2023-10-03
申请号：US17972399
申请日：2022-10-24
Applicant: Renagade Therapeutics Management Inc.
Inventor： Muthusamy Jayaraman , Stephen Scully
IPC: C07D207/08 , C07D401/06 , C07D211/34
CPC classification number: C07D207/08 , C07D211/34 , C07D401/06
Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
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公开(公告)号：US20240200118A1
公开(公告)日：2024-06-20
申请号：US18443407
申请日：2024-02-16
Applicant: Renagade Therapeutics Management Inc.
Inventor： Inna SHCHERBAKOVA , Grace CHEN , Abril Fleitas BEITANS , Brian GOODMAN , Ciaran LAWLOR , Kevin Yingxin YANG
CPC classification number: C12Q1/025 , A61K47/10 , A61K47/543 , A61K48/0025
Abstract: The present disclosure details various compositions and/or methods of optimizing delivery systems the localized delivery of nucleic acid sequences, polypeptides or peptides for use in therapeutics and/or diagnostics.
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公开(公告)号：US20240084274A1
公开(公告)日：2024-03-14
申请号：US18297346
申请日：2023-04-07
Applicant: ReNAgade Therapeutics Management Inc.
Inventor： Giedrius Gasiunas , Alim Ladha , Vladimir Presnyak , Muthusamy Jayaraman
CPC classification number: C12N9/22 , C12N9/78 , C12N9/1276 , C12Y207/07049 , C12N15/902 , C07K2319/09 , C07K2319/85 , C12N2310/20
Abstract: The present disclosure provides methods and compositions comprising novel Cas TypeV programmable nucleases and lipid nanoparticles capable of delivering the Cas TypeV programmable nucleases and genome editing systems comprising same. For therapeutic applications, as well as plants and industrial biotechnology.
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Patent Agency Ranking
公开(公告)号：US20240067598A1
公开(公告)日：2024-02-29
申请号：US18223855
申请日：2023-07-19
Applicant: ReNAgade Therapeutics Management Inc.
Inventor： Stephen Scully , Muthusamy Jayaraman , Ganapathy Subramanian Sankaran
IPC: C07C229/12 , A61K9/51 , A61K48/00 , C07D233/61 , C07J41/00 , C07D277/56 , C07D277/28
CPC classification number: C07C229/12 , A61K9/5123 , A61K48/0033 , C07D233/61 , C07J41/0088 , C07D277/56 , C07D277/28 , C07C2603/74 , C07C2602/38 , C07C2602/44 , C07C2602/42
Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
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公开(公告)号：US20230235365A1
公开(公告)日：2023-07-27
申请号：US18087673
申请日：2022-12-22
Applicant: ReNAgade Therapeutics Management Inc.
Inventor： Alim Ladha , Vladimir Presnyak , Brian Goodman , Mario Rodriguez Mestre , Devin Scott Quinlan , Muthusamy Jayaraman , Stephen Scully
CPC classification number: C12N15/907 , C12N15/11 , C12N9/22 , C12N9/1276 , C12N2310/20 , C12N2310/531 , C12N2800/80
Abstract: Disclosed are engineered retrons and methods of use such as to modify the genome of a host (e.g., mammalian) cell by delivering the engineered retron or the encoded ncRNA in vitro or in vivo to the host (e.g., mammalian) cell.
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公开(公告)号：US12215068B2
公开(公告)日：2025-02-04
申请号：US18223855
申请日：2023-07-19
Applicant: ReNAgade Therapeutics Management Inc.
Inventor： Stephen Scully , Muthusamy Jayaraman , Ganapathy Subramanian Sankaran
IPC: C07C229/12 , A61K9/51 , A61K48/00 , C07D233/61 , C07D277/28 , C07D277/56 , C07J41/00
Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
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公开(公告)号：US12054739B2
公开(公告)日：2024-08-06
申请号：US18472824
申请日：2023-09-22
Applicant: ReNAgade Therapeutics Management Inc.
Inventor： Alim Ladha , Vladimir Presnyak , Inna Shcherbakova , Brian Goodman , Mario Rodriguez Mestre , Devin Scott Quinlan , Muthusamy Jayaraman , Stephen Scully
CPC classification number: C12N15/907 , C12N9/1276 , C12N9/22 , C12N15/11 , C12N2310/20 , C12N2310/531 , C12N2800/80
Abstract: Disclosed are engineered retrons and methods of use such as to modify the genome of a host (e.g., mammalian) cell by delivering the engineered retron or the encoded ncRNA in vitro or in vivo to the host (e.g., mammalian) cell.
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公开(公告)号：US20240182412A1
公开(公告)日：2024-06-06
申请号：US18335836
申请日：2023-06-15
Applicant: ReNAgade Therapeutics Management Inc.
Inventor： Muthusamy Jayaraman , Stephen Scully
IPC: C07D207/08 , C07D211/34 , C07D401/06
CPC classification number: C07D207/08 , C07D211/34 , C07D401/06
Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
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