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公开(公告)号:US20230202966A1
公开(公告)日:2023-06-29
申请号:US17972395
申请日:2022-10-24
Applicant: Renagade Therapeutics Management Inc.
Inventor: Muthusamy Jayaraman , Stephen Scully
IPC: C07C219/06 , C07C219/08 , C07C219/10
CPC classification number: C07C219/06 , C07C219/08 , C07C219/10
Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
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公开(公告)号:US11773061B2
公开(公告)日:2023-10-03
申请号:US17972399
申请日:2022-10-24
Applicant: Renagade Therapeutics Management Inc.
Inventor: Muthusamy Jayaraman , Stephen Scully
IPC: C07D207/08 , C07D401/06 , C07D211/34
CPC classification number: C07D207/08 , C07D211/34 , C07D401/06
Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
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公开(公告)号:US20240067598A1
公开(公告)日:2024-02-29
申请号:US18223855
申请日:2023-07-19
Applicant: ReNAgade Therapeutics Management Inc.
Inventor: Stephen Scully , Muthusamy Jayaraman , Ganapathy Subramanian Sankaran
IPC: C07C229/12 , A61K9/51 , A61K48/00 , C07D233/61 , C07J41/00 , C07D277/56 , C07D277/28
CPC classification number: C07C229/12 , A61K9/5123 , A61K48/0033 , C07D233/61 , C07J41/0088 , C07D277/56 , C07D277/28 , C07C2603/74 , C07C2602/38 , C07C2602/44 , C07C2602/42
Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
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公开(公告)号:US20230235365A1
公开(公告)日:2023-07-27
申请号:US18087673
申请日:2022-12-22
Applicant: ReNAgade Therapeutics Management Inc.
Inventor: Alim Ladha , Vladimir Presnyak , Brian Goodman , Mario Rodriguez Mestre , Devin Scott Quinlan , Muthusamy Jayaraman , Stephen Scully
CPC classification number: C12N15/907 , C12N15/11 , C12N9/22 , C12N9/1276 , C12N2310/20 , C12N2310/531 , C12N2800/80
Abstract: Disclosed are engineered retrons and methods of use such as to modify the genome of a host (e.g., mammalian) cell by delivering the engineered retron or the encoded ncRNA in vitro or in vivo to the host (e.g., mammalian) cell.
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公开(公告)号:US12215068B2
公开(公告)日:2025-02-04
申请号:US18223855
申请日:2023-07-19
Applicant: ReNAgade Therapeutics Management Inc.
Inventor: Stephen Scully , Muthusamy Jayaraman , Ganapathy Subramanian Sankaran
IPC: C07C229/12 , A61K9/51 , A61K48/00 , C07D233/61 , C07D277/28 , C07D277/56 , C07J41/00
Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
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公开(公告)号:US12054739B2
公开(公告)日:2024-08-06
申请号:US18472824
申请日:2023-09-22
Applicant: ReNAgade Therapeutics Management Inc.
Inventor: Alim Ladha , Vladimir Presnyak , Inna Shcherbakova , Brian Goodman , Mario Rodriguez Mestre , Devin Scott Quinlan , Muthusamy Jayaraman , Stephen Scully
CPC classification number: C12N15/907 , C12N9/1276 , C12N9/22 , C12N15/11 , C12N2310/20 , C12N2310/531 , C12N2800/80
Abstract: Disclosed are engineered retrons and methods of use such as to modify the genome of a host (e.g., mammalian) cell by delivering the engineered retron or the encoded ncRNA in vitro or in vivo to the host (e.g., mammalian) cell.
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公开(公告)号:US20240182412A1
公开(公告)日:2024-06-06
申请号:US18335836
申请日:2023-06-15
Applicant: ReNAgade Therapeutics Management Inc.
Inventor: Muthusamy Jayaraman , Stephen Scully
IPC: C07D207/08 , C07D211/34 , C07D401/06
CPC classification number: C07D207/08 , C07D211/34 , C07D401/06
Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
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公开(公告)号:US20240175058A1
公开(公告)日:2024-05-30
申请号:US18472824
申请日:2023-09-22
Applicant: ReNAgade Therapeutics Management Inc.
Inventor: Alim Ladha , Vladimir Presnyak , Inna Shcherbakova , Brian Goodman , Mario Rodriguez Mestre , Devin Scott Quinlan , Muthusamy Jayaraman , Stephen Scully
CPC classification number: C12N15/907 , C12N9/1276 , C12N9/22 , C12N15/11 , C12N2310/20 , C12N2310/531 , C12N2800/80
Abstract: Disclosed are engineered retrons and methods of use such as to modify the genome of a host (e.g., mammalian) cell by delivering the engineered retron or the encoded ncRNA in vitro or in vivo to the host (e.g., mammalian) cell.
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公开(公告)号:US11866728B2
公开(公告)日:2024-01-09
申请号:US18087673
申请日:2022-12-22
Applicant: ReNAgade Therapeutics Management Inc.
Inventor: Alim Ladha , Vladimir Presnyak , Inna Shcherbakova , Brian Goodman , Mario Rodriguez Mestre , Devin Scott Quinlan , Muthusamy Jayaraman , Stephen Scully
CPC classification number: C12N15/907 , C12N9/1276 , C12N9/22 , C12N15/11 , C12N2310/20 , C12N2310/531 , C12N2800/80
Abstract: Disclosed are engineered retrons and methods of use such as to modify the genome of a host (e.g., mammalian) cell by delivering the engineered retron or the encoded ncRNA in vitro or in vivo to the host (e.g., mammalian) cell.
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公开(公告)号:US20230202977A1
公开(公告)日:2023-06-29
申请号:US17972399
申请日:2022-10-24
Applicant: Renagade Therapeutics Management Inc.
Inventor: Muthusamy Jayaraman , Stephen Scully
IPC: C07D207/08 , C07D211/34 , C07D401/06
CPC classification number: C07D207/08 , C07D211/34 , C07D401/06
Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
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