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公开(公告)号：US09585612B2
公开(公告)日：2017-03-07
申请号：US11361484
申请日：2006-02-24
CPC分类号： A61B5/413 , A61B1/00009 , A61B1/00186 , A61B1/043 , A61B1/0638 , A61B1/0646 , A61B1/307 , A61B5/0071 , A61B5/0084 , A61B5/721 , G01N21/6428 , G01N21/6456
摘要： A fluorescence diagnosis system has a viewing system at least one light source and a camera system. The at least one light source can be operated in three modes, a first generating white light, a second with a first fluorescence excitation light of a first excitation wavelength and a third in which a second fluorescence excitation light of a second excitation wavelength is generated producing a fluorescence image in the NIR range. The camera system is sensitive at least in the visible and the NIR range. The system further comprises an image processing system for converting the fluorescence image in the NIR range into a visible image.
摘要翻译： 荧光诊断系统具有至少一个光源和相机系统的观察系统。 所述至少一个光源可以以三种模式操作，第一产生白光，第二产生具有第一激发波长的第一荧光激发光，其中第三激发光产生第二激发波长的第二荧光激发光，产生产生 NIR范围内的荧光图像。 至少在可见光和近红外范围内，相机系统是敏感的。 该系统还包括用于将NIR范围内的荧光图像转换成可见图像的图像处理系统。
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公开(公告)号：US06212425B1
公开(公告)日：2001-04-03
申请号：US09043850
申请日：1998-09-18
IPC分类号： A61B500
CPC分类号： G01N21/6486 , A61B1/00186 , A61B1/043 , A61B1/055 , A61B1/0638 , A61B1/0646 , A61B5/0071 , A61B5/0084 , G01N21/6456
摘要： A device for “in vivo” diagnosis by means of a photosensibilisator light-induced reaction or a reaction caused by intrinsic fluorescence in biological tissue, having an illumination system, which is provided with at least one light source having a lamp system which generates incoherent light in a wavelength range of at least 380 to 680 nm, a light delivering unit which directs the light of said illumination system at the therapy and/or to-be-diagnosed tissue area, and an imaging, image-recording and image-transmitting unit which images the light coming from said tissue area in a proximal image plane. The device is distinguished in that the net spectral transmittance in the light delivering unit and in the image-generating unit of the device are selected in such a manner that, on the one hand, practically no light with a wavelength of &lgr; from the range utilized for excitation, which by nature has relatively high intensity, “reaches” via the image-generating unit of the device into the proximal image plane, whereas light with a wavelength of &lgr; from the range in which fluorescence occurs can reach the proximal image plane only if it comes from the illuminated tissue are and not from the illumination system.
摘要翻译： 一种用于通过光敏效应器光诱导反应或由生物组织中的固有荧光引起的反应进行的“体内”诊断的装置，具有照明系统，其具有至少一个具有产生不相干光的灯系统的光源 在至少380至680nm的波长范围内，将所述照明系统的光引导到治疗和/或待诊断的组织区域的光输送单元，以及成像，图像记录和图像发送单元 其在近端图像平面中对来自所述组织区域的光进行成像。 该装置的特征在于，以这样的方式选择装置中的光输送单元和图像生成单元中的净光谱透射率，一方面实际上不具有从所使用的范围的羔羊波长的光 对于本质上具有相对高强度的激发，通过装置的图像生成单元“到达”到近端图像平面中，而从发生荧光的范围的波长为lamb的光可以仅到达近端图像平面 如果它来自照明组织而不是来自照明系统。
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公开(公告)号：US20060241499A1
公开(公告)日：2006-10-26
申请号：US11361484
申请日：2006-02-24
IPC分类号： A61B6/00
CPC分类号： A61B5/413 , A61B1/00009 , A61B1/00186 , A61B1/043 , A61B1/0638 , A61B1/0646 , A61B1/307 , A61B5/0071 , A61B5/0084 , A61B5/721 , G01N21/6428 , G01N21/6456
摘要： A fluorescence diagnosis system has a viewing system at least one light source and a camera system. The at least one light source can be operated in three modes, a first generating white light, a second with a first fluorescence excitation light of a first excitation wavelength and a third in which a second fluorescence excitation light of a second excitation wavelength is generated producing a fluorescence image in the NIR range. The camera system is sensitive at least in the visible and the NIR range. The system further comprises an image processing system for converting the fluorescence image in the NIR range into a visible image.
摘要翻译： 荧光诊断系统具有至少一个光源和相机系统的观察系统。 所述至少一个光源可以以三种模式操作，第一产生白光，第二产生具有第一激发波长的第一荧光激发光，其中第三激发光产生第二激发波长的第二荧光激发光，产生产生 NIR范围内的荧光图像。 至少在可见光和近红外范围内，相机系统是敏感的。 该系统还包括用于将NIR范围内的荧光图像转换成可见图像的图像处理系统。
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4.发明授权Apparatus for generating various laser wavelengths from the same laser medium 失效用于从相同激光介质产生各种激光波长的装置
公开(公告)号：US4920541A
公开(公告)日：1990-04-24
申请号：US357654
申请日：1989-05-25
CPC分类号： H01S3/082 , H01S3/08004 , H01S3/08086 , H01S3/107
摘要： An apparatus for producing various laser wavelengths from the same laser medium by means of resonator mirrors. In accordance with the apparatus any desired, given combination of laser wavelengths can be brought to emission simultaneously or at least in very rapid alternation (switching time 1 ms) with the use of standard resonator mirrors linearly arranged outside of a laser medium, with part of at least one of the resonator mirrors being configured so that it serves as resonator limitation for a certain laser wavelength or wavelength group but another part of the at least one of the resonator mirrors constitutes an intracavity element for the respective other wavelength(s) or wavelength group(s).
摘要翻译： 一种用于通过谐振器反射镜从同一激光介质产生各种激光波长的装置。 根据该装置，任何期望的，给定的激光波长的组合可以同时或至少以非常快速的交替（切换时间1ms）发射，使用线性布置在激光介质外部的标准谐振镜，其中一部分 谐振器反射镜中的至少一个被配置为使得其用作特定激光波长或波长组的谐振器限制，但是至少一个谐振器反射镜的另一部分构成用于各个其它波长或波长的腔内元件 组。
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