利索-全球专利检索

  1. Login
  2. Sign Up

Search Results

94 records (took 0.029 seconds)

    EXPANDABLE CASING PATCH
    2.
    发明申请
    EXPANDABLE CASING PATCH 有权
    可扩展套管

    公开(公告)号：US20130206426A1

    公开(公告)日：2013-08-15

    申请号：US13880594

    申请日：2011-10-18

    Applicant: Richard Murray Whiddon

    Inventor： Richard Murray Whiddon

    IPC: E21B29/10 ,  E21B43/10

    CPC classification number: E21B29/10 ,  E21B43/103 ,  E21B43/105 ,  E21B43/106 ,  E21B43/108

    Abstract: A system comprising a housing having an upper end in fluid communication with a source of pressurized fluid and a lower end releasably coupled to an expandable tubular. A piston is disposed within and sealingly engaged with the housing. An expansion cone is coupled to the piston and is operable to radially expand the expandable tubular as it moves longitudinally therethrough. A pressure chamber is disposed within the housing and defined by the piston and the expansion cone. A first pressure relief port is disposed within the housing and is operable to allow fluid communication between the pressure chamber and an annulus external to the housing. A second pressure relief port is disposed within the expansion cone and is operable to allow fluid communication between the pressure chamber and a portion of the expandable tubular below the expansion cone.

    Abstract translation: 一种系统，包括具有与加压流体源流体连通的上端的壳体和可释放地联接到可膨胀管的下端。 活塞设置在壳体内并与壳体密封接合。 膨胀锥体联接到活塞并且可操作以在可膨胀管道纵向移动通过其中径向膨胀。 压力室设置在壳体内并由活塞和膨胀锥限定。 第一压力释放口设置在壳体内并且可操作以允许压力室与外壳外部的环之间的流体连通。 第二减压口设置在膨胀锥体内并且可操作以允许压力室与膨胀锥体下方的可膨胀管的一部分之间的流体连通。

    Geometrically optimized expansion cone
    4.
    发明授权
    Geometrically optimized expansion cone 有权
    几何优化膨胀锥

    公开(公告)号：US08251137B2

    公开(公告)日：2012-08-28

    申请号：US12543809

    申请日：2009-08-19

    Applicant: Richard Murray Whiddon ,  Terry Dale Jones

    Inventor： Richard Murray Whiddon ,  Terry Dale Jones

    IPC: E21B23/04 ,  B21D39/08

    CPC classification number: E21B43/105

    Abstract: A geometrically optimized expansion cone for radially expanding a tubular member. In some embodiments, the expansion cone includes an annular body having an outer surface. The outer surface includes a linear surface having a constant diameter, a curvilinear surface extending from the linear surface, a recessed surface having a diameter less than the diameter of the curvilinear surface, and a chamfer between the recessed surface and the curvilinear surface. The diameter of the linear surface is substantially equal to an inner diameter of the tubular member after expansion, while the chamfer has a maximum diameter less than an inner diameter of the tubular member prior to expansion. The curvilinear surface has a diameter defined by a radius of curvature which is tangent to the chamfer at the maximum diameter and tangent to the linear surface.

    Abstract translation: 用于径向膨胀管状构件的几何优化的膨胀锥。 在一些实施例中，膨胀锥体包括具有外表面的环形体。 外表面包括具有恒定直径的线性表面，从线性表面延伸的曲线表面，具有小于曲线表面的直径的直径的凹入表面以及凹入表面和曲线表面之间的倒角。 线性表面的直径基本上等于膨胀后管状构件的内径，而倒角在膨胀之前具有小于管状构件的内径的最大直径。 曲线表面具有由曲率半径限定的直径，该曲率半径在最大直径处与倒角相切，并且与线性表面相切。

    Downhole release joint with radially expandable members
    5.
    发明授权
    Downhole release joint with radially expandable members 有权
    井下释放接头具有径向可扩张部件

    公开(公告)号：US08225877B2

    公开(公告)日：2012-07-24

    申请号：US12604007

    申请日：2009-10-22

    Applicant: Richard Murray Whiddon

    Inventor： Richard Murray Whiddon

    IPC: E21B43/10

    CPC classification number: E21B43/105 ,  E21B17/06 ,  E21B43/106

    Abstract: A downhole releasable tubing connection includes a joint between two tubing strings, wherein one of the two tubing strings is radially expanded and plastically deformed by an expansion device. When the expansion device is moved adjacent to the joint, a mechanism in the joint reacts to the radially outward forces of the expansion device and releasably expands, separates, breaks, or otherwise provides a release between the two tubing strings. One tubing string and the expansion device can then be removed to the surface of the well bore while the expanded tubing remains installed in the well bore.

    Abstract translation: 井下可释放管道连接包括两个油管柱之间的接头，其中两个油管柱之一通过膨胀装置径向膨胀和塑性变形。 当膨胀装置靠近接头移动时，接头中的机构与膨胀装置的径向向外的力反应并且可释放地膨胀，分离，断裂或以其它方式在两个管柱之间提供释放。 然后可以将一个油管柱和膨胀装置移除到井眼的表面，而膨胀的管道保持安装在井眼中。

    Use of Anti-Alpha5Beta1 Antibodies to Inhibit Cancer Cell Proliferation
    6.
    发明申请
    Use of Anti-Alpha5Beta1 Antibodies to Inhibit Cancer Cell Proliferation 审中-公开
    使用抗α5Beta1抗体抑制癌细胞增殖

    公开(公告)号：US20100291111A1

    公开(公告)日：2010-11-18

    申请号：US12642687

    申请日：2009-12-18

    Applicant: VANITHA RAMAKRISHNAN ,  VINAY BHASKAR ,  SUN HO ,  RICHARD MURRAY ,  DEBBIE LAW

    Inventor： VANITHA RAMAKRISHNAN ,  VINAY BHASKAR ,  SUN HO ,  RICHARD MURRAY ,  DEBBIE LAW

    IPC: A61K39/395 ,  A61P35/00 ,  A61P35/04

    CPC classification number: C07K16/2842 ,  A61K39/39558 ,  A61K2039/505 ,  C07K2317/55 ,  C07K2317/73 ,  A61K2300/00

    Abstract: The present invention provides methods for direct killing of cancer cells using anti-α5β1 antibodies. Generally, the method comprises contacting a cancer cell that expresses α5β1 on its surface with an anti-α5β1 antibody, and thereby inducing the death of the cancer cell. The methods of the invention may be employed at an early stage of cancer development in a patient to prevent tumor establishment. In addition, the methods may be used to treat previously formed tumors especially in cancer that have not proven susceptible to anti-angiogenesis therapy. The methods may be employed as a combination therapy of anti-α5β1 antibodies together with cancer chemotherapeutic agents or other molecular-based cancer therapeutic agents.

    Abstract translation: 本发明提供使用抗α5和bgr1抗体直接杀死癌细胞的方法。 通常，该方法包括使表面上表达α5和bgr1的癌细胞与抗α5和bgr1抗体接触，从而诱导癌细胞的死亡。 本发明的方法可以在患者的癌症发展的早期阶段中使用，以防止肿瘤的形成。 此外，该方法可用于治疗先前形成的肿瘤，特别是在尚未被证实易于进行抗血管生成治疗的癌症中。 该方法可以用作抗α5和bgr1抗体与癌症化学治疗剂或其它基于分子的癌症治疗剂的组合疗法。

    Use of anti-α5β1 antibodies to inhibit cancer cell proliferation
    7.
    发明授权
    Use of anti-α5β1 antibodies to inhibit cancer cell proliferation 失效
    使用抗α5beta1抗体抑制癌细胞增殖

    公开(公告)号：US07662384B2

    公开(公告)日：2010-02-16

    申请号：US11090331

    申请日：2005-03-24

    Applicant: Vanitha Ramakrishnan ,  Vinay Bhaskar ,  Sun Ho ,  Richard Murray ,  Debbie Law

    Inventor： Vanitha Ramakrishnan ,  Vinay Bhaskar ,  Sun Ho ,  Richard Murray ,  Debbie Law

    IPC: A61K39/395

    CPC classification number: C07K16/2842 ,  A61K39/39558 ,  A61K2039/505 ,  C07K2317/55 ,  C07K2317/73 ,  A61K2300/00

    Abstract: The present invention provides methods for direct killing of cancer cells using anti-α5β1 antibodies. Generally, the method comprises contacting a cancer cell that expresses α5β1 on its surface with an anti-α5β1 antibody, and thereby inducing the death of the cancer cell. The methods of the invention may be employed at an early stage of cancer development in a patient to prevent tumor establishment. In addition, the methods may be used to treat previously formed tumors especially in cancer that have not proven susceptible to anti-angiogenesis therapy. The methods may be employed as a combination therapy of anti-α5β1 antibodies together with cancer chemotherapeutic agents or other molecular-based cancer therapeutic agents.

    Abstract translation: 本发明提供使用抗α5β1抗体直接杀死癌细胞的方法。 通常，该方法包括将表面上的α5β1的癌细胞与抗α5β1抗体接触，从而诱导癌细胞的死亡。 本发明的方法可以在患者的癌症发展的早期阶段中使用，以防止肿瘤的形成。 此外，该方法可用于治疗先前形成的肿瘤，特别是在尚未被证实易于进行抗血管生成治疗的癌症中。 该方法可以用作抗α5β1抗体与癌症化学治疗剂或其它基于分子的癌症治疗剂的组合疗法。

    Multi-stage mechanical delay mechanisms for inertial igniters for thermal batteries and the like
    8.
    发明授权
    Multi-stage mechanical delay mechanisms for inertial igniters for thermal batteries and the like 有权
    用于热电池等的惯性点火器的多级机械延迟机构

    公开(公告)号：US07587979B2

    公开(公告)日：2009-09-15

    申请号：US11888815

    申请日：2007-08-02

    Applicant: Jahangir S. Rastegar ,  Richard Murray ,  Thomas Spinelli

    Inventor： Jahangir S. Rastegar ,  Richard Murray ,  Thomas Spinelli

    IPC: F42C15/24 ,  F42C15/34

    CPC classification number: F42C11/008 ,  F42C9/02 ,  F42C15/24

    Abstract: An inertia igniter including a mechanical delay mechanism having two or more members which are movable under different acceleration conditions to sequentially move a movable member upon sequential movement of the two or more members and an ignition member actuatable by the movable member such that movement of the movable member by the two or more members ignites the ignition member. The movable member can be movable by one of translation and rotation. The inertia igniter can further comprise an impact mass releasably movable in the housing, wherein the impact mass is released and movable by movement of the movable member to impact the ignition member. The inertia igniter can also further comprise a stop member for preventing movement of the impact mass until the movable member has moved a predetermined distance.

    Abstract translation: 一种惯性点火器，其包括具有两个或更多个构件的机械延迟机构，所述机构延迟机构可在不同的加速条件下移动，以在所述两个或多个构件的顺序移动时顺序地移动可动构件，以及可由所述可移动构件致动的点火构件， 由两个或多个构件构件点燃点火构件。 可移动构件可以通过平移和旋转之一移动。 惯性点火器还可以包括在壳体中可释放地移动的冲击质量，其中冲击质量被释放并且可移动通过可移动构件的冲击而撞击点火构件。 惯性点火器还可以进一步包括止动构件，用于防止冲击块的运动，直到可移动构件已经移动预定距离。

Patent Agency Ranking