公开(公告)号：US20070196238A1

公开(公告)日：2007-08-23

申请号：US11648050

申请日：2006-12-28

申请人： Colin Kennedy ,  Syed Husain ,  Dale von Behren ,  Rick Bernal

发明人： Colin Kennedy ,  Syed Husain ,  Dale von Behren ,  Rick Bernal

IPC分类号： G01N15/06

CPC分类号： G01N1/38 ,  G01N13/00 ,  G01N33/15 ,  G01N35/025 ,  G01N2013/003 ,  G01N2013/006 ,  G01N2035/00198

摘要： The invention provides a system and method for dissolution testing. The system includes multiple dissolution vessels and a dose carrier positioned above the dissolution vessels. The dose carrier holds multiple removable carousels that receive individual doses for dissolution tested. Carousels that receive tablets or sinkers typically have a first configuration, while carousels that receive baskets typically have a second configuration. The two different configurations of carousels are interchangeable on the same dose ring. The system further includes a drive head positioned above the dose carrier, the drive head having a basket arbor and a mixing paddle removably and interchangeably attached. A pipettor integral with the system transfers sample aliquots having volumes in the range of 50 μl to 1 ml from the dissolution vessels to wells of an external receptacle.

摘要翻译： 本发明提供了用于溶出度测试的系统和方法。 该系统包括多个溶解容器和位于溶解容器上方的剂量载体。 剂量载体保持多个可移除的转盘，其接收单独的剂量以进行溶解测试。 接收片剂或沉降片的转盘通常具有第一配置，而接收篮子的转盘通常具有第二配置。 转盘的两种不同配置可在相同的剂量环上互换。 所述系统还包括位于所述剂量载体上方的驱动头，所述驱动头具有篮状心轴和可移除地且可互换地连接的混合桨。 与系统整合的移液器将样品等分试样从溶出容器转移至50ml至1ml的范围至外部容器的孔。

公开(公告)号：US08518327B2

公开(公告)日：2013-08-27

申请号：US13437414

申请日：2012-04-02

申请人： Colin B. Kennedy ,  Syed Husain ,  Dale von Behren ,  Rick Bernal

发明人： Colin B. Kennedy ,  Syed Husain ,  Dale von Behren ,  Rick Bernal

IPC分类号： G01N21/00

CPC分类号： G01N1/38 ,  G01N13/00 ,  G01N33/15 ,  G01N35/025 ,  G01N2013/003 ,  G01N2013/006 ,  G01N2035/00198

摘要： The invention provides a system and method for dissolution testing. The system includes multiple dissolution vessels and a dose carrier positioned above the dissolution vessels. The dose carrier holds multiple removable carousels that receive individual doses for dissolution tested. Carousels that receive tablets or sinkers typically have a first configuration, while carousels that receive baskets typically have a second configuration. The two different configurations of carousels are interchangeable on the same dose ring. The system further includes a drive head positioned above the dose carrier, the drive head having a basket arbor and a mixing paddle removably and interchangeably attached. A pipettor integral with the system transfers sample aliquots having volumes in the range of 50 μl to 1 ml from the dissolution vessels to wells of an external receptacle.

摘要翻译： 本发明提供了用于溶出度测试的系统和方法。 该系统包括多个溶解容器和位于溶解容器上方的剂量载体。 剂量载体保持多个可移除的转盘，其接收单独的剂量以进行溶解测试。 接收片剂或沉降片的转盘通常具有第一配置，而接收篮子的转盘通常具有第二配置。 转盘的两种不同配置可在相同的剂量环上互换。 所述系统还包括位于所述剂量载体上方的驱动头，所述驱动头具有篮状心轴和可移除地且可互换地连接的混合桨。 与系统整合的移液器将样品等分试样从溶出容器转移至50ml至1ml的范围至外部容器的孔。

公开(公告)号：US20120255346A1

公开(公告)日：2012-10-11

申请号：US13437414

申请日：2012-04-02

申请人： Colin Kennedy ,  Syed Husain ,  Dale von Behren ,  Rick Bernal

发明人： Colin Kennedy ,  Syed Husain ,  Dale von Behren ,  Rick Bernal

IPC分类号： G01N1/10

CPC分类号： G01N1/38 ,  G01N13/00 ,  G01N33/15 ,  G01N35/025 ,  G01N2013/003 ,  G01N2013/006 ,  G01N2035/00198

摘要： The invention provides a system and method for dissolution testing. The system includes multiple dissolution vessels and a dose carrier positioned above the dissolution vessels. The dose carrier holds multiple removable carousels that receive individual doses for dissolution tested. Carousels that receive tablets or sinkers typically have a first configuration, while carousels that receive baskets typically have a second configuration. The two different configurations of carousels are interchangeable on the same dose ring. The system further includes a drive head positioned above the dose carrier, the drive head having a basket arbor and a mixing paddle removably and interchangeably attached. A pipettor integral with the system transfers sample aliquots having volumes in the range of 50 μl to 1 ml from the dissolution vessels to wells of an external receptacle.

摘要翻译： 本发明提供了用于溶出度测试的系统和方法。 该系统包括多个溶解容器和位于溶解容器上方的剂量载体。 剂量载体保持多个可移除的转盘，其接收单独的剂量以进行溶解测试。 接收片剂或沉降片的转盘通常具有第一配置，而接收篮子的转盘通常具有第二配置。 转盘的两种不同配置可在相同的剂量环上互换。 所述系统还包括位于所述剂量载体上方的驱动头，所述驱动头具有篮状心轴和可移除地且可互换地连接的混合桨。 与系统整合的移液器将从溶出容器到外部容器的孔的体积范围为50μl至1ml的样品等分试样。

公开(公告)号：US08158059B2

公开(公告)日：2012-04-17

申请号：US11648050

申请日：2006-12-28

申请人： Colin Kennedy ,  Syed Husain ,  Dale von Behren ,  Rick Bernal

发明人： Colin Kennedy ,  Syed Husain ,  Dale von Behren ,  Rick Bernal

IPC分类号： G01N21/00

CPC分类号： G01N1/38 ,  G01N13/00 ,  G01N33/15 ,  G01N35/025 ,  G01N2013/003 ,  G01N2013/006 ,  G01N2035/00198

摘要： The invention provides a system and method for dissolution testing. The system includes multiple dissolution vessels and a dose carrier positioned above the dissolution vessels. The dose carrier holds multiple removable carousels that receive individual doses for dissolution tested. Carousels that receive tablets or sinkers typically have a first configuration, while carousels that receive baskets typically have a second configuration. The two different configurations of carousels are interchangeable on the same dose ring. The system further includes a drive head positioned above the dose carrier, the drive head having a basket arbor and a mixing paddle removably and interchangeably attached. A pipettor integral with the system transfers sample aliquots having volumes in the range of 50 μl to 1 ml from the dissolution vessels to wells of an external receptacle.

摘要翻译： 本发明提供了用于溶出度测试的系统和方法。 该系统包括多个溶解容器和位于溶解容器上方的剂量载体。 剂量载体保持多个可移除的转盘，其接收单独的剂量以进行溶解测试。 接收片剂或沉降片的转盘通常具有第一配置，而接收篮子的转盘通常具有第二配置。 转盘的两种不同配置可在相同的剂量环上互换。 所述系统还包括位于所述剂量载体上方的驱动头，所述驱动头具有篮状心轴和可移除地且可互换地连接的混合桨。 与系统整合的移液器将从溶出容器到外部容器的孔的体积范围为50μl至1ml的样品等分试样。