公开(公告)号：US20080065204A1

公开(公告)日：2008-03-13

申请号：US11981025

申请日：2007-10-31

申请人： John Macoviak ,  Robert Chang ,  David Rahdert ,  Timothy Machold ,  Rick Soss

发明人： John Macoviak ,  Robert Chang ,  David Rahdert ,  Timothy Machold ,  Rick Soss

IPC分类号： A61F2/24

CPC分类号： A61F2/2445 ,  A61F2/2418 ,  A61F2/2454

摘要： An implant for supplementing, repairing, or replacing a native heart valve leaflet or leaflets provides a scaffold, which defines a pseudo-annulus. The implant further has at least two struts in generally oppositely spaced apart positions on the scaffold. The scaffold can be placed in an elastically loaded condition in a heart with the struts engaging tissue at or near the leaflet commissures of a heart valve annulus, to reshape the annulus for leaflet coaptation. The implant further provides a neoleaflet element coupled to the scaffold within pseudo-annulus, to provide a one-way valve function.

摘要翻译： 用于补充，修复或更换天然心脏瓣膜小叶或小叶的植入物提供了一种支架，其限定了假环形瓣。 植入物还具有至少两个在支架上相对间隔开的位置的支柱。 支架可以放置在心脏中的弹性加载状态，其中支柱将组织接合在心脏瓣膜环的小叶连接处或附近，以重新形成瓣膜以进行小叶接合。 植入物还提供在假环形空间内连接到支架的新翼元件，以提供单向阀功能。

公开(公告)号：US20060069430A9

公开(公告)日：2006-03-30

申请号：US10676729

申请日：2003-10-01

申请人： David Rahdert ,  John Macoviak ,  Timothy Machold ,  Robert Chang ,  Rick Soss

发明人： David Rahdert ,  John Macoviak ,  Timothy Machold ,  Robert Chang ,  Rick Soss

IPC分类号： A61F2/24

CPC分类号： A61F2/2454

摘要： Devices, systems and methods retain a native heart valve leaflet to prevent retrograde flow. The devices, systems, and methods employ an implant that, in use, rests adjacent a valve annulus and includes a retaining structure that is sized and shaped to overlay at least a portion of one or more native valve leaflets. The retaining structure retains the leaflet or leaflets it overlays, to resist leaflet eversion and/or prolapse. In this way, the implant prevents or reduces regurgitation. The implant does not interfere significantly with the opening of and blood flow through the leaflets during periods of antegrade flow.

公开(公告)号：US20060106456A9

公开(公告)日：2006-05-18

申请号：US10677104

申请日：2003-10-01

申请人： Timothy Machold ,  David Rahdert ,  John Macoviak ,  Robert Chang ,  Rick Soss

发明人： Timothy Machold ,  David Rahdert ,  John Macoviak ,  Robert Chang ,  Rick Soss

IPC分类号： A61F2/24

CPC分类号： A61F2/2412 ,  A61B17/22012 ,  A61B18/1492 ,  A61B90/00 ,  A61B90/50 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/22097 ,  A61B2017/320052 ,  A61B2018/00392 ,  A61F2/2445 ,  A61F2/2454 ,  A61F2/2466 ,  Y10S623/904

摘要： Devices, systems, and methods employ an implant that is sized and configured to attach to the annulus of a dysfunctional heart valve annulus. In use, the implant extends across the major axis of the annulus above and/or along the valve annulus. The implant reshapes the major axis dimension and/or other surrounding anatomic structures. The implant restores to the heart valve annulus and leaflets a more functional anatomic shape and tension. The more functional anatomic shape and tension are conducive to coaptation of the leaflets, which, in turn, reduces retrograde flow or regurgitation. The implant improves function to the valve, without surgically cinching, resecting, and/or fixing in position large portions of a dilated annulus, or without the surgical fixation of ring-like structures.

摘要翻译： 装置，系统和方法采用尺寸和构造成附着到功能障碍性心脏瓣膜环的环的植入物。 在使用中，植入物跨过瓣膜环上方和/或沿着瓣膜环的环的长轴延伸。 植入物重塑长轴尺寸和/或其他周围的解剖结构。 植入物恢复到心脏瓣膜环，并具有更多功能的解剖形状和张力。 功能更多的解剖形状和张力有利于小叶的接合，这又降低逆行流动或反流。 植入物可以改善瓣膜的功能，而无需外科手术收紧，切除和/或固定在扩张的环的大部分位置，或无环状结构的手术固定。

公开(公告)号：US20050010287A1

公开(公告)日：2005-01-13

申请号：US10676815

申请日：2003-10-01

申请人： John Macoviak ,  Robert Chang ,  David Rahdert ,  Timothy Machold ,  Rick Soss

发明人： John Macoviak ,  Robert Chang ,  David Rahdert ,  Timothy Machold ,  Rick Soss

IPC分类号： A61F20060101 ,  A61F2/24

CPC分类号： A61F2/2445 ,  A61F2/2418 ,  A61F2/2454

摘要： Devices, systems and methods supplement, repair, or replace a native heart valve. The devices, systems, and methods employ an implant that, in use, extends adjacent a valve annulus. The implant includes a mobile neoleaflet element that occupies the space of at least a portion of one native valve leaflet. The implant mimics the one-way valve function of a native leaflet, to resist or prevent retrograde flow. The implant restores normal coaptation of the leaflets to resist retrograde flow, thereby resisting eversion and/or prolapse, which, in turn, reduces regurgitation.

公开(公告)号：US20050267573A9

公开(公告)日：2005-12-01

申请号：US10676815

申请日：2003-10-01

申请人： John Macoviak ,  Robert Chang ,  David Rahdert ,  Timothy Machold ,  Rick Soss

发明人： John Macoviak ,  Robert Chang ,  David Rahdert ,  Timothy Machold ,  Rick Soss

IPC分类号： A61F20060101 ,  A61F2/24

CPC分类号： A61F2/2445 ,  A61F2/2418 ,  A61F2/2454

摘要： Devices, systems and methods supplement, repair, or replace a native heart valve. The devices, systems, and methods employ an implant that, in use, extends adjacent a valve annulus. The implant includes a mobile neoleaflet element that occupies the space of at least a portion of one native valve leaflet. The implant mimics the one-way valve function of a native leaflet, to resist or prevent retrograde flow. The implant restores normal coaptation of the leaflets to resist retrograde flow, thereby resisting eversion and/or prolapse, which, in turn, reduces regurgitation.

摘要翻译： 装置，系统和方法补充，修理或更换原生心脏瓣膜。 装置，系统和方法采用在使用中邻近瓣膜环延伸的植入物。 植入物包括占据一个天然瓣膜小叶的至少一部分的空间的移动的新叶元件。 植入物模拟天然小叶的单向瓣膜功能，以抵抗或防止逆行流动。 植入物恢复小叶的正常接合以抵抗逆行流动，从而抵抗外翻和/或脱垂，这进而降低反流。