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公开(公告)号：US20070292849A1
公开(公告)日：2007-12-20
申请号：US10578392
申请日：2005-12-29
申请人： Steven Mah , Carolyn Hoyal-Wrightson , Stefan Kammerer , Matthew Nelson , Andreas Braun , Rikard Reneland
发明人： Steven Mah , Carolyn Hoyal-Wrightson , Stefan Kammerer , Matthew Nelson , Andreas Braun , Rikard Reneland
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/156 , C12Q2600/158
摘要： Provided herein are methods for identifying a risk of low BMD in a subject, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating low BMD-related disorders, such as osteoporosis, and therapeutic and preventative methods applicable to osteoporosis. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
摘要翻译： 本文提供用于鉴定受试者中低BMD风险的方法，用于实施该方法的试剂和试剂盒，用于鉴定用于治疗低BMD相关病症（例如骨质疏松症）的候选治疗剂的方法，以及适用于骨质疏松症的治疗和预防方法。 这些实施方案基于对人类基因组内核苷酸序列的多态变异的分析。
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公开(公告)号：US07510835B2
公开(公告)日：2009-03-31
申请号：US10723681
申请日：2003-11-25
申请人： Richard B. Roth , Matthew Roberts Nelson , Stefan M. Kammerer , Andreas Braun , Rikard Reneland
发明人： Richard B. Roth , Matthew Roberts Nelson , Stefan M. Kammerer , Andreas Braun , Rikard Reneland
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/156 , C12Q2600/172 , G01N33/57415 , G01N2800/52
摘要： Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
摘要翻译： 本文提供了用于鉴定受试者和/或患有乳腺癌风险的受试者的乳腺癌风险的方法，用于实施该方法的试剂和试剂盒，用于鉴定用于治疗乳腺癌的候选治疗剂的方法，以及用于治疗乳腺癌的治疗方法 在一个主题 这些实施方案基于对人类基因组内核苷酸序列的多态变异的分析。
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公开(公告)号：US20050272043A1
公开(公告)日：2005-12-08
申请号：US10857780
申请日：2004-05-27
申请人： Richard Roth , Andreas Braun , Stefan Kammerer , Matthew Nelson , Rikard Reneland , Carolyn Hoyal-Wrightson
发明人： Richard Roth , Andreas Braun , Stefan Kammerer , Matthew Nelson , Rikard Reneland , Carolyn Hoyal-Wrightson
IPC分类号： C12Q20060101 , C12Q1/68
CPC分类号： G01N33/57415 , C12Q1/6886 , C12Q2600/156 , C12Q2600/172
摘要： Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
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公开(公告)号：US20050064442A1
公开(公告)日：2005-03-24
申请号：US10723518
申请日：2003-11-25
申请人： Richard Roth , Josephine Atienza , Mikhail Denissenko , Andreas Braun , Stefan Kammerer , Matthew Nelson , Rikard Reneland
发明人： Richard Roth , Josephine Atienza , Mikhail Denissenko , Andreas Braun , Stefan Kammerer , Matthew Nelson , Rikard Reneland
IPC分类号： C07H21/04 , C12N20060101 , C12P19/34 , C12Q1/68 , G01N33/574
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/156 , C12Q2600/172
摘要： Provided herein are methods for identifying a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
摘要翻译： 本文提供了用于鉴定患有乳腺癌风险的受试者的方法，用于实施该方法的试剂和试剂盒，用于鉴定用于治疗乳腺癌的候选治疗剂的方法，以及用于治疗受试者的乳腺癌的治疗方法。 这些实施方案基于对人类基因组内核苷酸序列的多态变异的分析。
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公开(公告)号：US20060204967A1
公开(公告)日：2006-09-14
申请号：US10723683
申请日：2003-11-25
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/156 , C12Q2600/172 , G01N33/57415 , G01N2800/52
摘要： Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
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公开(公告)号：US20050214771A1
公开(公告)日：2005-09-29
申请号：US10722939
申请日：2003-11-25
IPC分类号： A61B20060101 , A61K20060101 , A61K48/00 , C07H21/02 , C07H21/04 , C07K14/72 , C12P19/34 , C12Q20060101 , C12Q1/68 , G01N33/574
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/156 , C12Q2600/172 , G01N33/57415 , G01N2800/52
摘要： Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
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公开(公告)号：US20050053958A1
公开(公告)日：2005-03-10
申请号：US10723142
申请日：2003-11-25
IPC分类号： A61B20060101 , A61K20060101 , A61K48/00 , C07H21/02 , C07H21/04 , C07K14/72 , C12P19/34 , C12Q20060101 , C12Q1/68 , G01N33/574
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/156 , C12Q2600/172 , G01N33/57415 , G01N2800/52
摘要： Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
摘要翻译： 本文提供了用于鉴定受试者和/或患有乳腺癌风险的受试者的乳腺癌风险的方法，用于实施该方法的试剂和试剂盒，用于鉴定用于治疗乳腺癌的候选治疗剂的方法，以及用于治疗乳腺癌的治疗方法 在一个主题 这些实施方案基于对人类基因组内核苷酸序列的多态变异的分析。
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公开(公告)号：US20090317816A1
公开(公告)日：2009-12-24
申请号：US12400724
申请日：2009-03-09
申请人： Richard B. Roth , Matthew Roberts Nelson , Stefan M. Kammerer , Andreas Braun , Rikard Reneland
发明人： Richard B. Roth , Matthew Roberts Nelson , Stefan M. Kammerer , Andreas Braun , Rikard Reneland
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/156 , C12Q2600/172 , G01N33/57415 , G01N2800/52
摘要： Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
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公开(公告)号：US20090258344A1
公开(公告)日：2009-10-15
申请号：US11570427
申请日：2004-05-27
申请人： Richard B. Roth , Matthew Roberts Nelson , Andreas Braun , Stefan M. Kammerer , Mikhail F. Denissenko , Rikard Reneland , Caridad Rosette , Carolyn R. Hoyal-Wrightson
发明人： Richard B. Roth , Matthew Roberts Nelson , Andreas Braun , Stefan M. Kammerer , Mikhail F. Denissenko , Rikard Reneland , Caridad Rosette , Carolyn R. Hoyal-Wrightson
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/172
摘要： Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
摘要翻译： 本文提供了用于鉴定受试者和/或患有乳腺癌风险的受试者的乳腺癌风险的方法，用于实施该方法的试剂和试剂盒，用于鉴定用于治疗乳腺癌的候选治疗剂的方法，以及用于治疗乳腺癌的治疗方法 在一个主题 这些实施方案基于对人类基因组内核苷酸序列的多态变异的分析。
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公开(公告)号：US20050192239A1
公开(公告)日：2005-09-01
申请号：US10723681
申请日：2003-11-25
IPC分类号： A61B20060101 , A61K20060101 , A61K48/00 , C07H21/02 , C07H21/04 , C07K14/72 , C12P19/34 , C12Q20060101 , C12Q1/68 , G01N33/574
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/156 , C12Q2600/172 , G01N33/57415 , G01N2800/52
摘要： Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
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