-
公开(公告)号：US20050064442A1
公开(公告)日：2005-03-24
申请号：US10723518
申请日：2003-11-25
申请人： Richard Roth , Josephine Atienza , Mikhail Denissenko , Andreas Braun , Stefan Kammerer , Matthew Nelson , Rikard Reneland
发明人： Richard Roth , Josephine Atienza , Mikhail Denissenko , Andreas Braun , Stefan Kammerer , Matthew Nelson , Rikard Reneland
IPC分类号： C07H21/04 , C12N20060101 , C12P19/34 , C12Q1/68 , G01N33/574
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/156 , C12Q2600/172
摘要： Provided herein are methods for identifying a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
摘要翻译： 本文提供了用于鉴定患有乳腺癌风险的受试者的方法，用于实施该方法的试剂和试剂盒，用于鉴定用于治疗乳腺癌的候选治疗剂的方法，以及用于治疗受试者的乳腺癌的治疗方法。 这些实施方案基于对人类基因组内核苷酸序列的多态变异的分析。
-
公开(公告)号：US20050118606A1
公开(公告)日：2005-06-02
申请号：US10723670
申请日：2003-11-25
申请人： Richard Roth , Caridad Rosette , Mikhail Denissenko , Matthew Nelson , Rikard Reneland , Andreas Braun , Stefan Kammerer
发明人： Richard Roth , Caridad Rosette , Mikhail Denissenko , Matthew Nelson , Rikard Reneland , Andreas Braun , Stefan Kammerer
IPC分类号： A61K48/00 , C12N20060101 , C12Q1/68
CPC分类号： C12Q1/6886 , A61K38/17 , C12Q2600/106 , C12Q2600/136 , C12Q2600/156 , C12Q2600/172
摘要： Provided herein are methods for identifying a risk of cancer in a subject and/or a subject at risk of cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating cancer, and therapeutic methods for treating cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in a KLF12 nucleic acid, which has a nucleotide sequence exemplified in SEQ ID NO: 1, 2 or 3.
摘要翻译： 本文提供了用于鉴定受试者和/或患有癌症风险的受试者的癌症风险的方法，用于实施该方法的试剂和试剂盒，用于鉴定用于治疗癌症的候选治疗剂的方法，以及用于治疗患者癌症的治疗方法 。 这些实施方案基于KLF12核酸中的多态性变异的分析，其具有SEQ ID NO：1,2或3所示核苷酸序列。
-
公开(公告)号：US20050272043A1
公开(公告)日：2005-12-08
申请号：US10857780
申请日：2004-05-27
申请人： Richard Roth , Andreas Braun , Stefan Kammerer , Matthew Nelson , Rikard Reneland , Carolyn Hoyal-Wrightson
发明人： Richard Roth , Andreas Braun , Stefan Kammerer , Matthew Nelson , Rikard Reneland , Carolyn Hoyal-Wrightson
IPC分类号： C12Q20060101 , C12Q1/68
CPC分类号： G01N33/57415 , C12Q1/6886 , C12Q2600/156 , C12Q2600/172
摘要： Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
-
公开(公告)号：US20050192239A1
公开(公告)日：2005-09-01
申请号：US10723681
申请日：2003-11-25
IPC分类号： A61B20060101 , A61K20060101 , A61K48/00 , C07H21/02 , C07H21/04 , C07K14/72 , C12P19/34 , C12Q20060101 , C12Q1/68 , G01N33/574
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/156 , C12Q2600/172 , G01N33/57415 , G01N2800/52
摘要： Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
-
公开(公告)号：US20060204967A1
公开(公告)日：2006-09-14
申请号：US10723683
申请日：2003-11-25
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/156 , C12Q2600/172 , G01N33/57415 , G01N2800/52
摘要： Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
-
公开(公告)号：US20050214771A1
公开(公告)日：2005-09-29
申请号：US10722939
申请日：2003-11-25
IPC分类号： A61B20060101 , A61K20060101 , A61K48/00 , C07H21/02 , C07H21/04 , C07K14/72 , C12P19/34 , C12Q20060101 , C12Q1/68 , G01N33/574
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/156 , C12Q2600/172 , G01N33/57415 , G01N2800/52
摘要： Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
-
公开(公告)号：US20050053958A1
公开(公告)日：2005-03-10
申请号：US10723142
申请日：2003-11-25
IPC分类号： A61B20060101 , A61K20060101 , A61K48/00 , C07H21/02 , C07H21/04 , C07K14/72 , C12P19/34 , C12Q20060101 , C12Q1/68 , G01N33/574
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/156 , C12Q2600/172 , G01N33/57415 , G01N2800/52
摘要： Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
摘要翻译： 本文提供了用于鉴定受试者和/或患有乳腺癌风险的受试者的乳腺癌风险的方法，用于实施该方法的试剂和试剂盒，用于鉴定用于治疗乳腺癌的候选治疗剂的方法，以及用于治疗乳腺癌的治疗方法 在一个主题 这些实施方案基于对人类基因组内核苷酸序列的多态变异的分析。
-
公开(公告)号：US20050118117A1
公开(公告)日：2005-06-02
申请号：US10703817
申请日：2003-11-06
申请人： Richard Roth , Matthew Nelson , Stefan Kammerer , Andreas Braun
发明人： Richard Roth , Matthew Nelson , Stefan Kammerer , Andreas Braun
IPC分类号： A61B20060101 , A61K31/4745 , A61K33/24 , A61K35/12 , A61K38/16 , A61K38/17 , A61K38/45 , A61K39/395 , A61K48/00 , A61P35/00 , C07H21/00 , C07K14/47 , C12N20060101 , C12N1/00 , C12N5/06 , C12N9/10 , C12N15/12 , C12N15/54 , C12Q1/68
CPC分类号： C07K14/4748 , C12Q1/6827
摘要： Provided herein are methods for identifying risk of melanoma in a subject and/or subjects at risk of melanoma, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating melanoma, therapeutic methods for treating melanoma in a subject and compositions comprising one or more melanoma cells and one or more NRP1, NID2 or ENDO180 directed agents. These embodiments are based upon an analysis of polymorphic variations in a NRP1, NID2 or ENDO180 nucleic acid, exemplified by nucleotide sequences of SEQ ID NO: 1, 2 or 3.
摘要翻译： 本文提供用于鉴定受试者和/或患有黑素瘤风险的受试者的黑素瘤风险的方法，用于实施该方法的试剂和试剂盒的方法，用于鉴定治疗黑素瘤的候选治疗剂的方法，用于治疗受试者的黑素瘤的治疗方法和包含 一种或多种黑素瘤细胞和一种或多种NRP1，NID2或ENDO180定向试剂。 这些实施方案基于NRP1，NID2或ENDO180核酸的多态性变异的分析，例如SEQ ID NO：1,2或3的核苷酸序列。
-
公开(公告)号：US20050233341A1
公开(公告)日：2005-10-20
申请号：US10840590
申请日：2004-05-05
CPC分类号： C12Q1/6886 , A61K31/4745 , A61K45/06 , C07K14/4748 , C12Q2600/106 , C12Q2600/136 , C12Q2600/156 , C12Q2600/172
摘要： Provided herein are methods for identifying risk of melanoma in a subject and/or subjects at risk of melanoma, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating melanoma, therapeutic methods for treating melanoma in a subject and compositions comprising one or more melanoma cells and one or more NRP1, NID2, ENDO180, CDK10, FPGT, CARK, PCLO or REPS2 directed agents. These embodiments are based upon an analysis of polymorphic variations in a NRP1, NID2, ENDO180, CDK10, FPGT, CARK, PCLO or REPS2 nucleic acid, exemplified by nucleotide sequences of SEQ ID NO: 1-17.
摘要翻译： 本文提供用于鉴定受试者和/或患有黑素瘤风险的受试者的黑素瘤风险的方法，用于实施该方法的试剂和试剂盒的方法，用于鉴定治疗黑素瘤的候选治疗剂的方法，用于治疗受试者的黑素瘤的治疗方法和包含 一种或多种黑素瘤细胞和一种或多种NRP1，NID2，ENDO180，CDK10，FPGT，CARK，PCLO或REPS2定向试剂。 这些实施方案基于NRP1，NID2，ENDO180，CDK10，FPGT，CARK，PCLO或REPS2核酸中的多态性变异的分析，例如SEQ ID NO：1-17的核苷酸序列。
-
公开(公告)号：US20050170500A1
公开(公告)日：2005-08-04
申请号：US10704513
申请日：2003-11-06
申请人： Richard Roth , Matthew Nelson , Stefan Kammerer , Andreas Braun
发明人： Richard Roth , Matthew Nelson , Stefan Kammerer , Andreas Braun
IPC分类号： A61B20060101 , A61K31/4745 , A61K33/24 , A61K35/12 , A61K38/16 , A61K38/17 , A61K38/45 , A61K39/395 , A61K48/00 , A61P35/00 , C07H21/00 , C07K14/47 , C12N20060101 , C12N1/00 , C12N5/06 , C12N9/10 , C12N15/12 , C12N15/54 , C12Q1/68
CPC分类号： C07K14/4748 , C12Q1/6827
摘要： Provided herein are methods for identifying risk of melanoma in a subject and/or subjects at risk of melanoma, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating melanoma, therapeutic methods for treating melanoma in a subject and compositions comprising one or more melanoma cells and one or more CDK10, FPGT, PCLO or REPS2 directed agents. These embodiments are based upon an analysis of polymorphic variations in a CDK10, FPGT, PCLO or REPS2 nucleic acid, exemplified by nucleotide sequences of SEQ ID NO: 1, 2, 3 or 4.
摘要翻译： 本文提供用于鉴定受试者和/或患有黑素瘤风险的受试者的黑素瘤风险的方法，用于实施该方法的试剂和试剂盒的方法，用于鉴定治疗黑素瘤的候选治疗剂的方法，用于治疗受试者的黑素瘤的治疗方法和包含 一种或多种黑素瘤细胞和一种或多种CDK10，FPGT，PCLO或REPS2导向剂。 这些实施方案基于CDK10，FPGT，PCLO或REPS2核酸中的多态性变异的分析，例如SEQ ID NO：1,2,3或4的核苷酸序列。
-
-
-
-
-
-
-
-
-
搜索结果
45 条记录 (耗时 0.062 秒)
