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公开(公告)号:US20130184474A1
公开(公告)日:2013-07-18
申请号:US13821318
申请日:2011-10-04
申请人: Robert Huet , Jean-Michel Joerger , Vivien Henryon
发明人: Robert Huet , Jean-Michel Joerger , Vivien Henryon
IPC分类号: C07C391/00 , C07C319/24 , C07D307/33 , C07C319/14
CPC分类号: C07C391/00 , C07C253/16 , C07C319/02 , C07C319/14 , C07C319/24 , C07D307/33 , C07C323/58 , C07C255/28
摘要: The invention relates to a method for preparing an amino acid, or its salts, from 2-aminobutyrolactone (2ABL), said amino acid fitting the formula I, XCH2CH2CHNH2COOH, wherein X is such that X− represents a nucleophilic ion, according to which N-carboxylation of 2-aminobutyrolactone (2ABL) is achieved with carbon dioxide, and the thereby obtained 2ABL carbamate is reactive with an XH reagent or its salts.
摘要翻译: 本发明涉及一种由2-氨基丁内酯(2ABL)制备氨基酸或其盐的方法,所述氨基酸适合式I,XCH2CH2CHNH2COOH,其中X表示X-表示亲核离子,根据该方法,N 用二氧化碳实现2-氨基丁内酯(2ABL)的羧化,由此得到的2ABL氨基甲酸酯与XH试剂或其盐反应。
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公开(公告)号:USD661747S1
公开(公告)日:2012-06-12
申请号:US29392757
申请日:2011-05-26
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公开(公告)号:US20130273623A1
公开(公告)日:2013-10-17
申请号:US13882372
申请日:2011-10-27
申请人: Thomas Walther , Hélène Cordier , Christopher Topham , Isabelle Andre , Magali Remaud-Simeon , Robert Huet , Jean-Marie Francois
发明人: Thomas Walther , Hélène Cordier , Christopher Topham , Isabelle Andre , Magali Remaud-Simeon , Robert Huet , Jean-Marie Francois
IPC分类号: C12P7/42
CPC分类号: C12P7/42 , C07F9/096 , C12N9/0006 , C12N9/0008 , C12N9/1217 , C12N15/70 , C12P7/40 , C12P9/00 , C12Y101/01 , C12Y102/01011 , C12Y102/01018 , C12Y207/02004
摘要: The present invention deals with a method of producing 2,4-dihydroxybutyric acid (2,4-DHB) by a synthetic pathway comprising the transformation of malate in 4-phospho-malate using a malate kinase, said 4-phospho-malate being transformed in malate-4-semialdehyde using a malate semialdehyde dehydrogenase and said malate-4-semialdehyde being transformed in 2,4-DHB using a DHB dehydrogenase.
摘要翻译: 本发明涉及一种通过合成途径生产2,4-二羟基丁酸(2,4-DHB)的方法,该方法包括使用苹果酸激酶在4-磷酸苹果酸中转化苹果酸,所述4-磷酸苹果酸酯被转化 在苹果酸4-半醛中使用苹果酸半醛脱氢酶,并且使用DHB脱氢酶在2,4-DHB中转化所述苹果酸4-半醛。
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公开(公告)号:US3091155A
公开(公告)日:1963-05-28
申请号:US9257161
申请日:1961-03-01
申请人: ROBERT HUET JEAN
发明人: ROBERT HUET JEAN
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公开(公告)号:US09238829B2
公开(公告)日:2016-01-19
申请号:US13882372
申请日:2011-10-27
申请人: Thomas Walther , Helene Cordier , Christopher Topham , Isabelle Andre , Magali Remaud-Simeon , Robert Huet , Jean-Marie Francois
发明人: Thomas Walther , Helene Cordier , Christopher Topham , Isabelle Andre , Magali Remaud-Simeon , Robert Huet , Jean-Marie Francois
CPC分类号: C12P7/42 , C07F9/096 , C12N9/0006 , C12N9/0008 , C12N9/1217 , C12N15/70 , C12P7/40 , C12P9/00 , C12Y101/01 , C12Y102/01011 , C12Y102/01018 , C12Y207/02004
摘要: A method of producing 2,4-dihydroxybutyric acid (2,4-DHB) by a synthetic pathway that includes the transforming malate in 4-phospho-malate using a malate kinase, said 4-phospho-malate being transformed in malate-4-semialdehyde using a malate semialdehyde dehydrogenase and said malate-4-semialdehyde being transformed in 2,4-DHB using a DHB dehydrogenase.
摘要翻译: 一种通过合成途径生产2,4-二羟基丁酸(2,4-DHB)的方法,该方法包括使用苹果酸激酶在4-磷酸苹果酸中转化苹果酸,所述4-磷酸苹果酸酯转化为苹果酸4- 使用苹果酸半醛脱氢酶的半醛,并使用DHB脱氢酶在2,4-DHB中转化所述苹果酸4-半醛。
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公开(公告)号:US08853428B2
公开(公告)日:2014-10-07
申请号:US13821318
申请日:2011-10-04
申请人: Robert Huet , Jean-Michel Joerger , Vivien Henryon
发明人: Robert Huet , Jean-Michel Joerger , Vivien Henryon
IPC分类号: C07D307/00
CPC分类号: C07C391/00 , C07C253/16 , C07C319/02 , C07C319/14 , C07C319/24 , C07D307/33 , C07C323/58 , C07C255/28
摘要: The invention relates to a method for preparing an amino acid, or its salts, from 2-aminobutyrolactone (2ABL), said amino acid fitting the formula I, XCH2CH2CHNH2COOH, wherein X is such that X− represents a nucleophilic ion, according to which N-carboxylation of 2-aminobutyrolactone (2ABL) is achieved with carbon dioxide, and the thereby obtained 2ABL carbamate is reactive with an XH reagent or its salts.
摘要翻译: 本发明涉及一种由2-氨基丁内酯(2ABL)制备氨基酸或其盐的方法,所述氨基酸适合式I,XCH2CH2CHNH2COOH,其中X表示X-表示亲核离子,根据该方法,N 用二氧化碳实现2-氨基丁内酯(2ABL)的羧化,由此得到的2ABL氨基甲酸酯与XH试剂或其盐反应。
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