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公开(公告)号:US09238829B2
公开(公告)日:2016-01-19
申请号:US13882372
申请日:2011-10-27
申请人: Thomas Walther , Helene Cordier , Christopher Topham , Isabelle Andre , Magali Remaud-Simeon , Robert Huet , Jean-Marie Francois
发明人: Thomas Walther , Helene Cordier , Christopher Topham , Isabelle Andre , Magali Remaud-Simeon , Robert Huet , Jean-Marie Francois
CPC分类号: C12P7/42 , C07F9/096 , C12N9/0006 , C12N9/0008 , C12N9/1217 , C12N15/70 , C12P7/40 , C12P9/00 , C12Y101/01 , C12Y102/01011 , C12Y102/01018 , C12Y207/02004
摘要: A method of producing 2,4-dihydroxybutyric acid (2,4-DHB) by a synthetic pathway that includes the transforming malate in 4-phospho-malate using a malate kinase, said 4-phospho-malate being transformed in malate-4-semialdehyde using a malate semialdehyde dehydrogenase and said malate-4-semialdehyde being transformed in 2,4-DHB using a DHB dehydrogenase.
摘要翻译: 一种通过合成途径生产2,4-二羟基丁酸(2,4-DHB)的方法,该方法包括使用苹果酸激酶在4-磷酸苹果酸中转化苹果酸,所述4-磷酸苹果酸酯转化为苹果酸4- 使用苹果酸半醛脱氢酶的半醛,并使用DHB脱氢酶在2,4-DHB中转化所述苹果酸4-半醛。
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公开(公告)号:US20130273623A1
公开(公告)日:2013-10-17
申请号:US13882372
申请日:2011-10-27
申请人: Thomas Walther , Hélène Cordier , Christopher Topham , Isabelle Andre , Magali Remaud-Simeon , Robert Huet , Jean-Marie Francois
发明人: Thomas Walther , Hélène Cordier , Christopher Topham , Isabelle Andre , Magali Remaud-Simeon , Robert Huet , Jean-Marie Francois
IPC分类号: C12P7/42
CPC分类号: C12P7/42 , C07F9/096 , C12N9/0006 , C12N9/0008 , C12N9/1217 , C12N15/70 , C12P7/40 , C12P9/00 , C12Y101/01 , C12Y102/01011 , C12Y102/01018 , C12Y207/02004
摘要: The present invention deals with a method of producing 2,4-dihydroxybutyric acid (2,4-DHB) by a synthetic pathway comprising the transformation of malate in 4-phospho-malate using a malate kinase, said 4-phospho-malate being transformed in malate-4-semialdehyde using a malate semialdehyde dehydrogenase and said malate-4-semialdehyde being transformed in 2,4-DHB using a DHB dehydrogenase.
摘要翻译: 本发明涉及一种通过合成途径生产2,4-二羟基丁酸(2,4-DHB)的方法,该方法包括使用苹果酸激酶在4-磷酸苹果酸中转化苹果酸,所述4-磷酸苹果酸酯被转化 在苹果酸4-半醛中使用苹果酸半醛脱氢酶,并且使用DHB脱氢酶在2,4-DHB中转化所述苹果酸4-半醛。
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