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16 条记录 (耗时 0.021 秒)

    Detection of human papillomavirus by the polymerase chain reaction
    1.
    发明授权
    Detection of human papillomavirus by the polymerase chain reaction 失效
    通过聚合酶链反应检测人乳头瘤病毒

    公开(公告)号：US5527898A

    公开(公告)日：1996-06-18

    申请号：US474542

    申请日：1995-06-07

    申请人： Heidi M. Bauer ,  Patti E. Gravitt ,  Catherine E. Greer ,  M. Michele Manos ,  Robert M. Resnick ,  Tracy Y. Zhang

    发明人： Heidi M. Bauer ,  Patti E. Gravitt ,  Catherine E. Greer ,  M. Michele Manos ,  Robert M. Resnick ,  Tracy Y. Zhang

    IPC分类号： C12Q1/68 ,  C12Q1/70 ,  C07H21/04

    CPC分类号： C12Q1/708

    摘要： The presence of human papillomavirus (HPV) in a sample can be detected and the HPV typed by a method that involves the amplification of HPV DNA sequences by the polymerase chain reaction (PCR). The primers used in the method are consensus primers that can be used to amplify a particular region of the genome of any HPV. The presence of HPV in a sample is indicated by the formation of amplified DNA. The HPV nucleic acid is detected by consensus probes that may be short oligonucleotide probes or long generic probes. The HPV is typed by the use of type-specific DNA probes specific for the amplified region of DNA.

    摘要翻译： 可以检测样品中人乳头状瘤病毒（HPV）的存在，并通过聚合酶链反应（PCR）扩增HPV DNA序列的方法进行HPV分型。 该方法中使用的引物是可用于扩增任何HPV基因组特定区域的共有引物。 通过形成扩增的DNA表明样品中存在HPV。 通过可能是短寡核苷酸探针或长泛型探针的共有探针检测HPV核酸。 通过使用特异于DNA扩增区的特异性DNA探针来分类HPV。

    Methods, primers and probes for detection of hepatitis C and novel variants
    2.
    发明授权
    Methods, primers and probes for detection of hepatitis C and novel variants 失效
    用于检测丙型肝炎和新型变体的方法，引物和探针

    公开(公告)号：US5527669A

    公开(公告)日：1996-06-18

    申请号：US240547

    申请日：1994-05-10

    申请人： Robert M. Resnick ,  Karen K. Y. Young

    发明人： Robert M. Resnick ,  Karen K. Y. Young

    IPC分类号： C12N7/00 ,  C07K14/18 ,  C12N15/09 ,  C12N15/51 ,  C12Q1/70 ,  C07H21/04 ,  C12Q1/68

    CPC分类号： C07K14/005 ,  C12Q1/707 ,  C12N2770/24222

    摘要： Oligonucleotides primers can be used to amplify and detect Hepatitis C virus nucleic acids in a process that involves reverse transcription of the viral genomic RNA to create cDNA and the subsequent amplification of the cDNA by the polymerase chain reaction. Oligonucleotide probes can be used to detect the presence of amplified DNA by hybridization. The invention provides improved methods, compositions, and kits for amplifying and detecting U.S., Japan, and HCV-C prototype nucleic acids.

    摘要翻译： 寡核苷酸引物可用于扩增和检测丙型肝炎病毒核酸，其涉及病毒基因组RNA的逆转录以产生cDNA并通过聚合酶链反应随后扩增cDNA。 寡核苷酸探针可用于通过杂交检测扩增的DNA的存在。 本发明提供用于扩增和检测美国，日本和HCV-C原型核酸的改进的方法，组合物和试剂盒。

    Primers and probes for detection of hepatitis C and novel variants
    3.
    发明授权
    Primers and probes for detection of hepatitis C and novel variants 失效
    用于检测丙型肝炎和新型变体的引物和探针

    公开(公告)号：US5580718A

    公开(公告)日：1996-12-03

    申请号：US449626

    申请日：1995-05-24

    申请人： Robert M. Resnick ,  Karen K. Y. Young

    发明人： Robert M. Resnick ,  Karen K. Y. Young

    IPC分类号： C12N7/00 ,  C07K14/18 ,  C12N15/09 ,  C12N15/51 ,  C12Q1/70 ,  C12Q1/68 ,  C07H21/04 ,  C12P19/34

    CPC分类号： C07K14/005 ,  C12Q1/707 ,  C12N2770/24222

    摘要： Oligonucleotides primers can be used to amplify and detect Hepatitis C virus nucleic acids in a process that involves reverse transcription of the viral genomic RNA to create cDNA and the subsequent amplification of the cDNA by the polymerase chain reaction. Oligonucleotide probes can be used to detect the presence of amplified DNA by hybridization. The invention provides improved methods, compositions, and kits for amplifying and detecting U.S., Japan, and HCV-C prototype nucleic acids.

    摘要翻译： 寡核苷酸引物可用于扩增和检测丙型肝炎病毒核酸，其涉及病毒基因组RNA的逆转录以产生cDNA并通过聚合酶链反应随后扩增cDNA。 寡核苷酸探针可用于通过杂交检测扩增的DNA的存在。 本发明提供用于扩增和检测美国，日本和HCV-C原型核酸的改进的方法，组合物和试剂盒。

    Supervisory Process Control And Manufacturing Information System Application Having A Layered Architecture
    6.
    发明申请
    Supervisory Process Control And Manufacturing Information System Application Having A Layered Architecture 有权
    具有层次结构的监督过程控制和制造信息系统应用

    公开(公告)号：US20100122269A1

    公开(公告)日：2010-05-13

    申请号：US12689962

    申请日：2010-01-19

    申请人： Robert M. Resnick ,  Laurence G. Leblanc ,  Timothy Sowell ,  Pankaj H. Mody

    发明人： Robert M. Resnick ,  Laurence G. Leblanc ,  Timothy Sowell ,  Pankaj H. Mody

    IPC分类号： G06F9/44 ,  G06F13/00 ,  G05B15/02

    CPC分类号： G06F9/44505 ,  G06F8/10 ,  G06F8/61

    摘要： A supervisory process control and manufacturing information system application is disclosed. The components of the application are distributable to a plurality of networked computer devices in a multi-layered hierarchical manner wherein lower layers host higher installed layers of application components. Application objects reside at a relatively high level of the distributed application architecture and model entities within a process control system. Engine objects host execution of the application objects in a run-time environment. Thus, application objects are not deployed until a host engine object with which they are associated have been deployed. Engine objects are hosted by platform objects. The platform objects correspond to a physical computer system component for executing the engine objects and associated application objects. A configuration facility presents a variety of views including deployment and model views of the application. The views incorporate the relationships of the objects that make up the distributed application.

    摘要翻译： 公开了一种监督过程控制和制造信息系统应用。 应用程序的组件可以多层次分层方式分发到多个联网计算机设备，其中较低层承载较高安装的应用组件层。 应用对象驻留在过程控制系统内的分布式应用程序架构和模型实体的较高级别。 引擎对象在运行时环境中托管应用程序对象的执行。 因此，在部署了与其关联的主机引擎对象之前，不会部署应用程序对象。 引擎对象由平台对象托管。 平台对象对应于用于执行引擎对象和相关应用对象的物理计算机系统组件。 配置工具提供了各种视图，包括应用程序的部署和模型视图。 视图包含构成分布式应用程序的对象的关系。

    Supervisory process control and manufacturing information system application having a layered architecture
    8.
    发明授权
    Supervisory process control and manufacturing information system application having a layered architecture 有权
    具有层次结构的监督过程控制和制造信息系统应用

    公开(公告)号：US07650607B2

    公开(公告)日：2010-01-19

    申请号：US10179668

    申请日：2002-06-24

    申请人： Robert M. Resnick ,  Laurence G. Leblanc ,  Timothy Sowell ,  Pankaj H. Mody

    发明人： Robert M. Resnick ,  Laurence G. Leblanc ,  Timothy Sowell ,  Pankaj H. Mody

    IPC分类号： G06F9/44 ,  G06F11/30 ,  G05B15/02

    CPC分类号： G06F9/44505 ,  G06F8/10 ,  G06F8/61

    摘要： A supervisory process control and manufacturing information system application is disclosed. The components of the application are distributable to a plurality of networked computer devices in a multi-layered hierarchical manner wherein lower layers host higher installed layers of application components. Application objects reside at a relatively high level of the distributed application architecture and model entities within a process control system. Engine objects host execution of the application objects in a run-time environment. Thus, application objects are not deployed until a host engine object with which they are associated have been deployed. Engine objects are hosted by platform objects. The platform objects correspond to a physical computer system component for executing the engine objects and associated application objects. A configuration facility presents a variety of views including deployment and model views of the application. The views incorporate the relationships of the objects that make up the distributed application.

    摘要翻译： 公开了一种监督过程控制和制造信息系统应用。 应用程序的组件可以多层次分层方式分发到多个联网计算机设备，其中较低层承载较高安装的应用组件层。 应用对象驻留在过程控制系统内的分布式应用程序架构和模型实体的较高级别。 引擎对象在运行时环境中托管应用程序对象的执行。 因此，在部署了与其关联的主机引擎对象之前，不会部署应用程序对象。 引擎对象由平台对象托管。 平台对象对应于用于执行引擎对象和相关应用对象的物理计算机系统组件。 配置工具提供了各种视图，包括应用程序的部署和模型视图。 视图包含构成分布式应用程序的对象的关系。

    Supervisory process control and manufacturing information system application having a layered architecture
    10.
    发明授权
    Supervisory process control and manufacturing information system application having a layered architecture 有权
    具有层次结构的监督过程控制和制造信息系统应用

    公开(公告)号：US08230443B2

    公开(公告)日：2012-07-24

    申请号：US12689962

    申请日：2010-01-19

    申请人： Robert M. Resnick ,  Laurence G. Leblanc ,  Timothy Sowell ,  Pankaj H. Mody

    发明人： Robert M. Resnick ,  Laurence G. Leblanc ,  Timothy Sowell ,  Pankaj H. Mody

    IPC分类号： G06F9/44 ,  G06F11/30 ,  G06B15/02

    CPC分类号： G06F9/44505 ,  G06F8/10 ,  G06F8/61

    摘要： A supervisory process control and manufacturing information system application is disclosed. The components of the application are distributable to a plurality of networked computer devices in a multi-layered hierarchical manner wherein lower layers host higher installed layers of application components. Application objects reside at a relatively high level of the distributed application architecture and model entities within a process control system. Engine objects host execution of the application objects in a run-time environment. Thus, application objects are not deployed until a host engine object with which they are associated have been deployed. Engine objects are hosted by platform objects. The platform objects correspond to a physical computer system component for executing the engine objects and associated application objects. A configuration facility presents a variety of views including deployment and model views of the application. The views incorporate the relationships of the objects that make up the distributed application.

    摘要翻译： 公开了一种监督过程控制和制造信息系统应用。 应用程序的组件可以多层次分层方式分发到多个联网计算机设备，其中较低层承载较高安装的应用组件层。 应用对象驻留在过程控制系统内的分布式应用程序架构和模型实体的较高级别。 引擎对象在运行时环境中托管应用程序对象的执行。 因此，在部署了与其关联的主机引擎对象之前，不会部署应用程序对象。 引擎对象由平台对象托管。 平台对象对应于用于执行引擎对象和相关应用对象的物理计算机系统组件。 配置工具提供了各种视图，包括应用程序的部署和模型视图。 视图包含构成分布式应用程序的对象的关系。