公开(公告)号：US20110320101A1

公开(公告)日：2011-12-29

申请号：US13227234

申请日：2011-09-07

申请人： Ronald Raby ,  Jordan Silberling

发明人： Ronald Raby ,  Jordan Silberling

IPC分类号： B64C25/46 ,  G06F19/00

CPC分类号： B64C25/46 ,  B60T8/1703 ,  B60T8/885 ,  B60T2270/402 ,  B60T2270/416

摘要： The method of maintaining optimal braking and skid protection for a two-wheeled vehicle wheel with a wheel speed sensor failure involves providing pulsed braking pressure to the affected wheel with the wheel speed sensor failure. If an incipient or initial skid on another wheel with a functioning wheel speed sensor has occurred, the pulsed braking pressure to the affected wheel is limited to the brake pressure command that caused the last incipient or initial skid on the other wheel, scaled by a factor for safety. Otherwise the pulsed braking pressure to the affected wheel is limited to be no greater than the greatest commanded brake pressure to the other wheel. The pulsed braking pressure is also limited to be less than the brake pressure commanded to the affected wheel.

公开(公告)号：US08083295B2

公开(公告)日：2011-12-27

申请号：US12174385

申请日：2008-07-16

申请人： Ronald Raby ,  Jordan Silberling

发明人： Ronald Raby ,  Jordan Silberling

IPC分类号： B60T8/86

CPC分类号： B64C25/46 ,  B60T8/1703 ,  B60T8/885 ,  B60T2270/402 ,  B60T2270/416

摘要： The method of maintaining optimal braking and skid protection for a two-wheeled vehicle wheel with a wheel speed sensor failure involves providing pulsed braking pressure to the affected wheel with the wheel speed sensor failure. If an incipient or initial skid on another wheel with a functioning wheel speed sensor has occurred, the pulsed braking pressure to the affected wheel is limited to the brake pressure command that caused the last incipient or initial skid on the other wheel, scaled by a factor for safety. Otherwise the pulsed braking pressure to the affected wheel is limited to be no greater than the greatest commanded brake pressure to the other wheel. The pulsed braking pressure is also limited to be less than the brake pressure commanded to the affected wheel.

摘要翻译： 对于具有车轮速度传感器故障的两轮车轮来说，保持最佳制动和防滑保护的方法包括：通过轮速传感器故障向受影响的车轮提供脉冲制动压力。 如果在具有功能的轮速传感器的另一个车轮上发生初始或初始滑行，则受影响的车轮的脉冲制动压力被限制在制动器压力指令，导致另一个车轮上的最初初始或初始滑行，按比例 为了安全。 否则，受影响的车轮的脉冲制动压力被限制在不大于另一个车轮的最大指令制动压力。 脉冲制动压力也被限制为小于指向受影响的车轮的制动压力。

公开(公告)号：US08326506B2

公开(公告)日：2012-12-04

申请号：US13227195

申请日：2011-09-07

申请人： Ronald Raby ,  Jordan Silberling

发明人： Ronald Raby ,  Jordan Silberling

IPC分类号： B60T7/12

CPC分类号： B64C25/46 ,  B60T8/1703 ,  B60T8/885 ,  B60T2270/402 ,  B60T2270/416

摘要： The method of maintaining optimal braking and skid protection for a two-wheeled vehicle wheel with a wheel speed sensor failure involves providing pulsed braking pressure to the affected wheel with the wheel speed sensor failure. If an incipient or initial skid on another wheel with a functioning wheel speed sensor has occurred, the pulsed braking pressure to the affected wheel is limited to the brake pressure command that caused the last incipient or initial skid on the other wheel, scaled by a factor for safety. Otherwise the pulsed braking pressure to the affected wheel is limited to be no greater than the greatest commanded brake pressure to the other wheel. The pulsed braking pressure is also limited to be less than the brake pressure commanded to the affected wheel.

摘要翻译： 对于具有车轮速度传感器故障的两轮车轮来说，保持最佳制动和防滑保护的方法包括：通过轮速传感器故障向受影响的车轮提供脉冲制动压力。 如果在具有功能的轮速传感器的另一个车轮上发生初始或初始滑行，则受影响的车轮的脉冲制动压力被限制在制动器压力指令，导致另一个车轮上的最初初始或初始滑行，按比例 为了安全。 否则，受影响的车轮的脉冲制动压力被限制在不大于另一个车轮的最大指令制动压力。 脉冲制动压力也被限制为小于指向受影响的车轮的制动压力。

公开(公告)号：US20100013296A1

公开(公告)日：2010-01-21

申请号：US12174385

申请日：2008-07-16

申请人： Ronald Raby ,  Jordan Silberling

发明人： Ronald Raby ,  Jordan Silberling

IPC分类号： B60T8/86

CPC分类号： B64C25/46 ,  B60T8/1703 ,  B60T8/885 ,  B60T2270/402 ,  B60T2270/416

摘要： The method of maintaining optimal braking and skid protection for a two-wheeled vehicle wheel with a wheel speed sensor failure involves providing pulsed braking pressure to the affected wheel with the wheel speed sensor failure. If an incipient or initial skid on another wheel with a functioning wheel speed sensor has occurred, the pulsed braking pressure to the affected wheel is limited to the brake pressure command that caused the last incipient or initial skid on the other wheel, scaled by a factor for safety. Otherwise the pulsed braking pressure to the affected wheel is limited to be no greater than the greatest commanded brake pressure to the other wheel. The pulsed braking pressure is also limited to be less than the brake pressure commanded to the affected wheel.

摘要翻译： 对于具有车轮速度传感器故障的两轮车轮来说，保持最佳制动和防滑保护的方法包括：通过轮速传感器故障向受影响的车轮提供脉冲制动压力。 如果在具有功能的轮速传感器的另一个车轮上发生初始或初始滑行，则受影响的车轮的脉冲制动压力被限制在制动器压力指令，导致另一个车轮上的最初初始或初始滑行，按比例 为了安全。 否则，受影响的车轮的脉冲制动压力被限制在不大于另一个车轮的最大指令制动压力。 脉冲制动压力也被限制为小于指向受影响的车轮的制动压力。

公开(公告)号：US08765065B2

公开(公告)日：2014-07-01

申请号：US13029198

申请日：2011-02-17

申请人： Luigi Martini ,  Philip Smith ,  Chi Leung Li ,  Ronald Raby

发明人： Luigi Martini ,  Philip Smith ,  Chi Leung Li ,  Ronald Raby

IPC分类号： B06B1/00

CPC分类号： A61K9/2866 ,  A61K9/0004 ,  A61K9/2846 ,  A61K9/2886 ,  B23B37/00

摘要： The present invention relates to a process using ultrasonic cutting for the preparation of an oral delivery device comprising a core which includes a pharmaceutically active agent covered by an outer coating which includes one or more openings communicating from the exterior of the device toward the core.

摘要翻译： 本发明涉及一种使用超声波切割来制备口服递送装置的方法，所述口腔递送装置包括芯，所述芯包括由外部涂层覆盖的药物活性剂，所述外部涂层包括从所述装置的外部朝向芯部连通的一个或多个开口。

公开(公告)号：US20110320100A1

公开(公告)日：2011-12-29

申请号：US13227195

申请日：2011-09-07

申请人： Ronald Raby ,  Jordan Silberling

发明人： Ronald Raby ,  Jordan Silberling

IPC分类号： B64C25/46 ,  G06F19/00

CPC分类号： B64C25/46 ,  B60T8/1703 ,  B60T8/885 ,  B60T2270/402 ,  B60T2270/416

摘要： The method of maintaining optimal braking and skid protection for a two-wheeled vehicle wheel with a wheel speed sensor failure involves providing pulsed braking pressure to the affected wheel with the wheel speed sensor failure. If an incipient or initial skid on another wheel with a functioning wheel speed sensor has occurred, the pulsed braking pressure to the affected wheel is limited to the brake pressure command that caused the last incipient or initial skid on the other wheel, scaled by a factor for safety. Otherwise the pulsed braking pressure to the affected wheel is limited to be no greater than the greatest commanded brake pressure to the other wheel. The pulsed braking pressure is also limited to be less than the brake pressure commanded to the affected wheel.

摘要翻译： 对于具有车轮速度传感器故障的两轮车轮来说，保持最佳制动和防滑保护的方法包括：通过轮速传感器故障向受影响的车轮提供脉冲制动压力。 如果在具有功能的轮速传感器的另一个车轮上发生初始或初始滑行，则受影响的车轮的脉冲制动压力被限制在制动器压力指令，导致另一个车轮上的最初初始或初始滑行，按比例 为了安全。 否则，受影响的车轮的脉冲制动压力被限制在不大于另一个车轮的最大指令制动压力。 脉冲制动压力也被限制为小于指向受影响的车轮的制动压力。

公开(公告)号：US20070178156A1

公开(公告)日：2007-08-02

申请号：US10598810

申请日：2005-03-11

申请人： Adrian Brown ,  Daniel Margetson ,  Wayne Matthews ,  Stephen McAllister ,  Ronald Raby

发明人： Adrian Brown ,  Daniel Margetson ,  Wayne Matthews ,  Stephen McAllister ,  Ronald Raby

IPC分类号： A61K9/24

CPC分类号： A61K9/1617 ,  A61K9/1623 ,  A61K9/1647 ,  A61K9/1652 ,  A61K9/4816 ,  A61K9/5026 ,  A61K9/5047 ,  A61K47/32

摘要： The present invention is directed to novel pharmaceutically acceptable polymeric compositions suitable for melt extrusion and injection molding of single or multi-component pharmaceutical dosage forms comprising a plurality of drug substance containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected together in the assembled dosage form.

摘要翻译： 本发明涉及适于熔融挤出和注射成型单组分或多组分药物剂型的新型药学上可接受的聚合物组合物，其包含多个含药物物质的子单元，即胶囊隔室和/或固体亚单元，其包含 含有药物的聚合物的固体基质，所述子单元在组装的剂型中连接在一起。

公开(公告)号：US20110131754A1

公开(公告)日：2011-06-09

申请号：US13029198

申请日：2011-02-17

申请人： Luigi MARTINI ,  Philip Smith ,  Chi Leung Li ,  Ronald Raby

发明人： Luigi MARTINI ,  Philip Smith ,  Chi Leung Li ,  Ronald Raby

IPC分类号： A47L9/00

CPC分类号： A61K9/2866 ,  A61K9/0004 ,  A61K9/2846 ,  A61K9/2886 ,  B23B37/00

摘要： The present invention relates to a process using ultrasonic cutting for the preparation of an oral delivery device comprising a core which includes a pharmaceutically active agent covered by an outer coating which includes one or more openings communicating from the exterior of the device toward the core.

摘要翻译： 本发明涉及一种使用超声波切割来制备口服递送装置的方法，所述口腔递送装置包括芯，所述芯包括由外部涂层覆盖的药物活性剂，所述外部涂层包括从所述装置的外部朝向芯部连通的一个或多个开口。

公开(公告)号：US07923027B2

公开(公告)日：2011-04-12

申请号：US10416116

申请日：2001-11-02

申请人： Luigi Martini ,  Philip Smith ,  Chi Leung Li ,  Ronald Raby

发明人： Luigi Martini ,  Philip Smith ,  Chi Leung Li ,  Ronald Raby

IPC分类号： A61K9/24

CPC分类号： A61K9/2866 ,  A61K9/0004 ,  A61K9/2846 ,  A61K9/2886 ,  B23B37/00

摘要： The present invention relates to a process using ultrasonic cutting for the preparation of an oral delivery device comprising a core which includes a pharmaceutically active agent covered by an outer coating which includes one or more openings communicating from the exterior of the device toward the core.

摘要翻译： 本发明涉及一种使用超声波切割来制备口服递送装置的方法，所述口腔递送装置包括芯，所述芯包括由外部涂层覆盖的药物活性剂，所述外部涂层包括从所述装置的外部朝向芯部连通的一个或多个开口。

公开(公告)号：US20100221292A1

公开(公告)日：2010-09-02

申请号：US12627330

申请日：2009-11-30

申请人： Allan J. Clarke ,  Robert Glinecke ,  Ronald Raby ,  Chi Leung Li ,  Luigi Martini

发明人： Allan J. Clarke ,  Robert Glinecke ,  Ronald Raby ,  Chi Leung Li ,  Luigi Martini

IPC分类号： A61K9/00 ,  B29C45/00

CPC分类号： A61K9/2072 ,  A61K9/0004 ,  A61K9/284 ,  A61K9/2893 ,  B29C45/14065 ,  B29C45/14073 ,  B29C2045/14122 ,  B29C2045/14155 ,  B29K2105/0035

摘要： An injection moulding process for the preparation of an oral delivery device comprising a core which contains a pharmaceutically active agent, having a coating with one or more openings leading to such a core. The invention also relates to devices produced by the process, and to injection moulds suitable for performing the process.

摘要翻译： 一种用于制备口服递送装置的注射模制方法，所述口腔递送装置包含含有药物活性剂的核心，所述药物活性剂具有具有通向所述核心的一个或多个开口的涂层。 本发明还涉及通过该方法生产的装置，以及适用于执行该方法的注射模具。