公开(公告)号：US20220290813A1

公开(公告)日：2022-09-15

申请号：US17517031

申请日：2021-11-02

申请人： Chao Liang ,  Seth A. Potratz ,  Lee J. Rosen ,  Hanfei Tuo ,  Rui Ma

发明人： Chao Liang ,  Seth A. Potratz ,  Lee J. Rosen ,  Hanfei Tuo ,  Rui Ma

IPC分类号： F17C7/04 ,  F17C13/02

摘要： A cryogenic vaporization system and a method for controlling the system are provided. The system includes a first vaporizer arrangement and a second vaporizer arrangement configured for receiving a liquid cryogen and outputting a superheated vapor. The second vaporizer arrangement is connected in parallel with the first vaporizer arrangement, and includes one or more banks of ambient air vaporizer (AAV) units or loose fill media with a high heat capacity. The second vaporizer arrangement has a different configuration than that of the first vaporizer arrangement. The system further includes at least one control valve controlling provision of the liquid cryogen to at least one of the first vaporizer arrangement and the second vaporizer arrangement.

公开(公告)号：US20220095968A1

公开(公告)日：2022-03-31

申请号：US17545711

申请日：2021-12-08

申请人： Liang Wang ,  Shwetha Edla ,  Ghazaleh R. Esmaili ,  Hossein Mohammadiarani ,  Sebastian Bohm ,  Rui Ma ,  Minglian Shi ,  Anna Harley-Trochimczyk

发明人： Liang Wang ,  Shwetha Edla ,  Ghazaleh R. Esmaili ,  Hossein Mohammadiarani ,  Sebastian Bohm ,  Rui Ma ,  Minglian Shi ,  Anna Harley-Trochimczyk

IPC分类号： A61B5/145 ,  A61B5/01 ,  A61B5/1468

摘要： Various examples are directed to systems and methods for generating an estimated analyte value. An analyte sensor system may access a first sensor signal from an in vivo analyte sensor and a first temperature signal from the ex vivo temperature sensor. The analyte sensor system may generate a first analyte sensor temperature based at least in part on the first temperature signal and generate a first estimated analyte value based at least in part on the first sensor signal and the first temperature-compensated sensitivity.

公开(公告)号：US20140004557A1

公开(公告)日：2014-01-02

申请号：US13991848

申请日：2012-01-13

申请人： Rui Ma ,  Lan Xie ,  Tian Qiu ,  Lei Wang ,  Wanli Xing

发明人： Rui Ma ,  Lan Xie ,  Tian Qiu ,  Lei Wang ,  Wanli Xing

IPC分类号： B01L3/00

CPC分类号： B01L3/5027 ,  C12M21/06 ,  C12M23/12 ,  C12M23/16

摘要： A micro fluidic device comprises one microstructure layer (5) and one cover layer (1), wherein the cover layer (1) is connected to the microstructure layer (5). The microstructure layer (5) comprises one bottom layer and a plurality of microstructures on it to position samples. The cover layer (1) comprises one top layer, one positioning well (6) and at least one inlet pool (4). The positioning well (6) is right above the microstructures and connected with each other. The inlet pools (4) and the positioning well (6) are connected by microchannels (3) which are formed between the microstructure layer (5) and the cover layer (1). The micro fluidic device can be applied in vitro fertilization, in determining how glial cells affect neurons, in constructing neural network and in detecting cell growth conditions.

摘要翻译： 微流体装置包括一个微结构层（5）和一个覆盖层（1），其中覆盖层（1）连接到微结构层（5）。 微结构层（5）包括一个底层和多个微结构，用于定位样品。 覆盖层（1）包括一个顶层，一个定位孔（6）和至少一个入口池（4）。 定位井（6）位于微结构的正上方并相互连接。 入口池（4）和定位井（6）通过形成在微结构层（5）和覆盖层（1）之间的微通道（3）连接。 微流体装置可以应用于体外受精，确定神经胶质细胞如何影响神经元，构建神经网络和检测细胞生长条件。

公开(公告)号：US08377889B2

公开(公告)日：2013-02-19

申请号：US13211558

申请日：2011-08-17

申请人： Michael Pugia ,  Rui Ma

发明人： Michael Pugia ,  Rui Ma

IPC分类号： A61K38/17

CPC分类号： C07K14/72 ,  A61K38/00

摘要： Methods are disclosed of treating diabetes, abnormal adipocyte activity, and insulin resistance using C-terminal fragments of adiponectin receptor R1. Methods of causing the secretion of insulin in healthy and diabetic patients using C-terminal fragments of adiponectin receptor R1 are also disclosed. In addition, methods are disclosed of increasing the insulin levels in healthy patients using C-terminal fragments of adiponectin receptor R1. In addition, methods of treating abnormal adipocyte activity, treating metabolic syndrome, causing insulin secretion, increasing insulin levels, inhibiting insulin degradation enzyme, treating Alzheimer's disease, treating cardiovascular disease associated with adiponectin levels, inhibiting ADAM-17 enzyme, treating a condition associated with TNF-alpha, and treating a condition associated with HER2-neu are disclosed. Compositions, dosage forms, and kits are also disclosed.

摘要翻译： 公开了使用脂联素受体R1的C末端片段治疗糖尿病，异常脂肪细胞活性和胰岛素抵抗的方法。 还公开了使用脂联素受体R1的C末端片段在健康和糖尿病患者中分泌胰岛素的方法。 此外，公开了使用脂联素受体R1的C末端片段增加健康患者的胰岛素水平的方法。 另外，处理异常脂肪细胞活性，治疗代谢综合征，引起胰岛素分泌，增加胰岛素水平，抑制胰岛素降解酶，治疗阿尔茨海默氏病，治疗与脂联素水平相关的心血管疾病，抑制ADAM-17酶，治疗与 公开了TNF-α和治疗与HER2-neu相关的病症。 还公开了组合物，剂型和试剂盒。

公开(公告)号：US20120069788A1

公开(公告)日：2012-03-22

申请号：US13256920

申请日：2009-07-27

申请人： Xiaoqin Shen ,  Rui Ma ,  Zhongda Du

发明人： Xiaoqin Shen ,  Rui Ma ,  Zhongda Du

IPC分类号： H04W74/08

CPC分类号： H04W74/006 ,  H04B7/2606 ,  H04W74/0833 ,  H04W74/0875 ,  H04W84/047

摘要： A random access method and a base station are provided, wherein the method comprises: a base station assigning a relay-dedicated random access preamble to a relay, wherein the relay-dedicated random access preamble indicates an access priority of the relay to be higher than that of an ordinary UE (S502); the base station receiving the relay-dedicated random access preamble sent from the relay and a random access preamble sent from the ordinary UE (S504); and the base station performing, when determining the relay-dedicated random access preamble is received, a non-contention-based random access preferentially for the relay (S506). Through the above processes, the time taken by random access of the relay to the network can be saved, and the success ratio of random access of the relay to the network is increased.

摘要翻译： 提供随机接入方法和基站，其中所述方法包括：向中继分配中继专用随机接入前导码的基站，其中所述中继专用随机接入前导码指示所述中继的接入优先级高于 普通UE的（S502）; 接收从中继发送的中继专用随机接入前导码的基站和从普通UE发送的随机接入前导码（S504）; 并且当确定接收到中继专用随机接入前同步码时，基站优先执行用于中继的非基于竞争的随机接入（S506）。 通过上述处理，可以节省继电器随机接入网络所需的时间，增加继电器随机接入成功率。

公开(公告)号：US20110301089A1

公开(公告)日：2011-12-08

申请号：US13211558

申请日：2011-08-17

申请人： Michael J. Pugia ,  Rui Ma

发明人： Michael J. Pugia ,  Rui Ma

IPC分类号： A61K38/17 ,  A61P9/00

CPC分类号： C07K14/72 ,  A61K38/00

摘要： Methods are disclosed of treating diabetes, abnormal adipocyte activity, and insulin resistance using C-terminal fragments of adiponectin receptor R1. Methods of causing the secretion of insulin in healthy and diabetic patients using C-terminal fragments of adiponectin receptor R1 are also disclosed. In addition, methods are disclosed of increasing the insulin levels in healthy patients using C-terminal fragments of adiponectin receptor R1. In addition, methods of treating abnormal adipocyte activity, treating metabolic syndrome, causing insulin secretion, increasing insulin levels, inhibiting insulin degradation enzyme, treating Alzheimer's disease, treating cardiovascular disease associated with adiponectin levels, inhibiting ADAM-17 enzyme, treating a condition associated with TNF-alpha, and treating a condition associated with HER2-neu are disclosed. Compositions, dosage forms, and kits are also disclosed.

摘要翻译： 公开了使用脂联素受体R1的C末端片段治疗糖尿病，异常脂肪细胞活性和胰岛素抵抗的方法。 还公开了使用脂联素受体R1的C末端片段在健康和糖尿病患者中分泌胰岛素的方法。 此外，公开了使用脂联素受体R1的C末端片段增加健康患者的胰岛素水平的方法。 另外，处理异常脂肪细胞活性，治疗代谢综合征，引起胰岛素分泌，增加胰岛素水平，抑制胰岛素降解酶，治疗阿尔茨海默氏病，治疗与脂联素水平相关的心血管疾病，抑制ADAM-17酶，治疗与 公开了TNF-α和治疗与HER2-neu相关的病症。 还公开了组合物，剂型和试剂盒。

公开(公告)号：US20110231448A1

公开(公告)日：2011-09-22

申请号：US13053360

申请日：2011-03-22

申请人： Keke Cai ,  Rui Ma ,  Zhong Su ,  Xiao Xun Zhang ,  Hui Jia Zhu

发明人： Keke Cai ,  Rui Ma ,  Zhong Su ,  Xiao Xun Zhang ,  Hui Jia Zhu

IPC分类号： G06F17/30

CPC分类号： G06F17/30864 ,  G06Q30/02

摘要： A device for generating opinion pairs having sentiment orientation based impact relations, having: a reception unit which receives a plurality of object-oriented opinions; an extraction unit which extracts opinions having impact relations among the plurality of object-oriented opinions; an analysis unit which analyzes sentiment orientations of the extracted respective opinions; and a generation unit which establishes correlations between the opinions having sentiment orientation based impact relations to generate the opinion pairs having the sentiment orientation based impact relations. The present device can search and locate more implicit opinions as supplementary opinions by detecting impact relations from a plurality of opinions, and help users interested in different objects obtain more comprehensive comments and summaries.

摘要翻译： 一种用于产生具有基于情绪取向的影响关系的意见对的装置，具有：接收多个面向对象意见的接收单元; 提取单元，提取多个面向对象意见之间具有影响关系的意见; 分析单位，分析提取的意见的情绪取向; 并建立了基于情绪导向的影响关系的观点之间的相关性的生成单位，以产生具有基于情绪取向的影响关系的意见对。 本设备可以通过检测多个意见的影响关系来搜索和定位更隐含的意见作为补充意见，并帮助对不同对象感兴趣的用户获得更全面的评论和摘要。

公开(公告)号：US08017573B2

公开(公告)日：2011-09-13

申请号：US12169983

申请日：2008-07-09

申请人： Michael J. Pugia ,  Rui Ma

发明人： Michael J. Pugia ,  Rui Ma

IPC分类号： A61K38/17

CPC分类号： C07K14/72 ,  A61K38/00

摘要： Methods are disclosed of treating diabetes, abnormal adipocyte activity, and insulin resistance using C-terminal fragments of adiponectin receptor R1. Methods of causing the secretion of insulin in healthy and diabetic patients using C-terminal fragments of adiponectin receptor R1 are also disclosed. In addition, methods are disclosed of increasing the insulin levels in healthy patients using C-terminal fragments of adiponectin receptor R1. In addition, methods of treating abnormal adipocyte activity, treating metabolic syndrome, causing insulin secretion, increasing insulin levels, inhibiting insulin degradation enzyme, treating Alzheimer's disease, treating cardiovascular disease associated with adiponectin levels, inhibiting ADAM-17 enzyme, treating a condition associated with TNF-alpha, and treating a condition associated with HER2-neu are disclosed. Compositions, dosage forms, and kits are also disclosed.

摘要翻译： 公开了使用脂联素受体R1的C末端片段治疗糖尿病，异常脂肪细胞活性和胰岛素抵抗的方法。 还公开了使用脂联素受体R1的C末端片段在健康和糖尿病患者中分泌胰岛素的方法。 此外，公开了使用脂联素受体R1的C末端片段增加健康患者的胰岛素水平的方法。 另外，处理异常脂肪细胞活性，治疗代谢综合征，引起胰岛素分泌，增加胰岛素水平，抑制胰岛素降解酶，治疗阿尔茨海默氏病，治疗与脂联素水平相关的心血管疾病，抑制ADAM-17酶，治疗与 公开了TNF-α和治疗与HER2-neu相关的病症。 还公开了组合物，剂型和试剂盒。

公开(公告)号：US20070290625A1

公开(公告)日：2007-12-20

申请号：US11762381

申请日：2007-06-13

申请人： Xi Yuan HE ,  Rui Ma ,  Giovanni Scilla

发明人： Xi Yuan HE ,  Rui Ma ,  Giovanni Scilla

IPC分类号： H05B41/16

CPC分类号： H02M3/3385 ,  H05B33/0815 ,  Y02B20/347

摘要： A driver arrangement for LED light sources includes a transformer having primary and secondary winding connections. A first electronic switch (SW1) controls current flow through the primary winding, and a sensing resistor is coupled to the primary winding to produce a current sensing signal. A second electronic switch (SW2) is sensitive to the sensing signal to switch off SW1 as current flow through the primary winding reaches a given threshold. SW1 is thus alternatively turned-on and off in alternating turn-on and switch-off phases to power the LED light source via the secondary winding. SW1 is a field effect transistor, preferably a MOSFET. The transformer is SELV-rated. The sensing resistor may be a variable resistor to adjust the duration of the on/off phases to permit controlled dimming.

摘要翻译： 用于LED光源的驱动装置包括具有初级和次级绕组连接的变压器。 第一电子开关（SW 1）控制通过初级绕组的电流，并且感测电阻器耦合到初级绕组以产生电流感测信号。 第二个电子开关（SW 2）对于感测信号敏感，以便通过初级绕组的电流流动达到给定的阈值来关闭SW 1。 SW 1因此在交替的导通和关断阶段中交替地导通和关闭，以通过次级绕组为LED光源供电。 SW 1是场效应晶体管，优选为MOSFET。 变压器额定电压为SELV。 感测电阻器可以是可变电阻器，以调节开/关相位的持续时间以允许受控的调光。

公开(公告)号：US11953159B2

公开(公告)日：2024-04-09

申请号：US17517031

申请日：2021-11-02

申请人： Chao Liang ,  Seth A. Potratz ,  Lee J. Rosen ,  Hanfei Tuo ,  Rui Ma

发明人： Chao Liang ,  Seth A. Potratz ,  Lee J. Rosen ,  Hanfei Tuo ,  Rui Ma

IPC分类号： F17C7/04 ,  F17C13/02

CPC分类号： F17C7/04 ,  F17C13/026 ,  F17C2250/032 ,  F17C2250/0439

摘要： A cryogenic vaporization system and a method for controlling the system are provided. The system includes a first vaporizer arrangement and a second vaporizer arrangement configured for receiving a liquid cryogen and outputting a superheated vapor. The second vaporizer arrangement is connected in parallel with the first vaporizer arrangement, and includes one or more banks of ambient air vaporizer (AAV) units or loose fill media with a high heat capacity. The second vaporizer arrangement has a different configuration than that of the first vaporizer arrangement. The system further includes at least one control valve controlling provision of the liquid cryogen to at least one of the first vaporizer arrangement and the second vaporizer arrangement.