利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

6 条记录 (耗时 0.014 秒)

    ORTHOGONAL ION INJECTION APPARATUS AND PROCESS
    1.
    发明申请
    ORTHOGONAL ION INJECTION APPARATUS AND PROCESS 有权
    正交离子注射装置和方法

    公开(公告)号：US20120298853A1

    公开(公告)日：2012-11-29

    申请号：US13114869

    申请日：2011-05-24

    申请人： Ruwan T. Kurulugama ,  Mikhail E. Belov

    发明人： Ruwan T. Kurulugama ,  Mikhail E. Belov

    IPC分类号： H01J49/22 ,  H01J49/00

    CPC分类号： H01J49/065 ,  H01J49/0404 ,  H01J49/044

    摘要： An orthogonal ion injection apparatus and process are described in which ions are directly injected into an ion guide orthogonal to the ion guide axis through an inlet opening located on a side of the ion guide. The end of the heated capillary is placed inside the ion guide such that the ions are directly injected into DC and RF fields inside the ion guide, which efficiently confines ions inside the ion guide. Liquid droplets created by the ionization source that are carried through the capillary into the ion guide are removed from the ion guide by a strong directional gas flow through an inlet opening on the opposite side of the ion guide. Strong DC and RF fields divert ions into the ion guide. In-guide orthogonal injection yields a noise level that is a factor of 1.5 to 2 lower than conventional inline injection known in the art. Signal intensities for low m/z ions are greater compared to convention inline injection under the same processing conditions.

    摘要翻译： 描述了一种正交离子注入装置和方法，其中离子通过位于离子导向器一侧的入口直接注入垂直于离子引导轴的离子导向器中。 加热的毛细管的末端放置在离子导向器内，使得离子直接注入到离子导向器内的DC和RF场中，这有效地将离子限制在离子导向器内。 由电离源产生的通过毛细管进入离子导向器的液滴通过强力的定向气流从离子导向器的相反侧的入口开口从离子导向器移除。 强直流和射频场将离子转移到离子导向器中。 导向正交注入产生比现有技术中已知的常规在线注入低1.5至2倍的噪声电平。 在相同的处理条件下，与常规的直线注入相比，低m / z离子的信号强度更大。

    Ion mobility spectrometer instrument and method of operation
    2.
    发明授权
    Ion mobility spectrometer instrument and method of operation 有权
    离子迁移光谱仪仪器及操作方法

    公开(公告)号：US08513591B2

    公开(公告)日：2013-08-20

    申请号：US12952109

    申请日：2010-11-22

    申请人： David E. Clemmer ,  Ruwan T. Kurulugama ,  Fabiane M. Nachtigall ,  Zachary Henson ,  Samuel I. Merenbloom ,  Stephen J. Valentine

    发明人： David E. Clemmer ,  Ruwan T. Kurulugama ,  Fabiane M. Nachtigall ,  Zachary Henson ,  Samuel I. Merenbloom ,  Stephen J. Valentine

    IPC分类号： H01J49/42

    CPC分类号： G01N27/622

    摘要： An ion mobility spectrometer instrument has a drift tube that is partitioned into a plurality of cascaded drift tube segments. A number of electric field activation sources may each be coupled to one or more of the plurality of drift tube segments. A control circuit is configured to control operation of the number of electric field activation sources in a manner that sequentially applies electric fields to the drift tube segments to allow only ions having a predefined ion mobility or range of ion mobilities to travel through the drift tube. The drift tube segments may define a linear drift tube or a closed drift tube with a continuous ion travel path. Techniques are disclosed for operating the ion mobility spectrometer to produce highly resolved ion mobility spectra.

    摘要翻译： 离子迁移谱仪具有漂移管，其被分隔成多个级联漂移管段。 多个电场激活源可以各自耦合到多个漂移管段中的一个或多个。 控制电路被配置为以顺序地向漂移管段施加电场以允许具有预定离子迁移率或离子迁移率范围的离子行进穿过漂移管的方式来控制电场激活源的数量的操作。 漂移管段可以限定具有连续离子行进路径的线性漂移管或闭合漂移管。 公开了用于操作离子迁移谱仪以产生高度分辨的离子迁移率光谱的技术。

    ION MOBILITY SPECTROMETER INSTRUMENT AND METHOD OF OPERATION
    3.
    发明申请
    ION MOBILITY SPECTROMETER INSTRUMENT AND METHOD OF OPERATION 有权
    离子移动光谱仪仪器和操作方法

    公开(公告)号：US20110121171A1

    公开(公告)日：2011-05-26

    申请号：US12952109

    申请日：2010-11-22

    申请人： David E. Clemmer ,  Ruwan T. Kurulugama ,  Fabiane M. Nachtigall ,  Zachary Henson ,  Samuel I. Merenbloom ,  Stephen J. Valentine

    发明人： David E. Clemmer ,  Ruwan T. Kurulugama ,  Fabiane M. Nachtigall ,  Zachary Henson ,  Samuel I. Merenbloom ,  Stephen J. Valentine

    IPC分类号： B01D59/44 ,  H01J49/40

    CPC分类号： G01N27/622

    摘要： An ion mobility spectrometer instrument has a drift tube that is partitioned into a plurality of cascaded drift tube segments. A number of electric field activation sources may each be coupled to one or more of the plurality of drift tube segments. A control circuit is configured to control operation of the number of electric field activation sources in a manner that sequentially applies electric fields to the drift tube segments to allow only ions having a predefined ion mobility or range of ion mobilities to travel through the drift tube. The drift tube segments may define a linear drift tube or a closed drift tube with a continuous ion travel path. Techniques are disclosed for operating the ion mobility spectrometer to produce highly resolved ion mobility spectra.

    摘要翻译： 离子迁移谱仪具有漂移管，其被分隔成多个级联漂移管段。 多个电场激活源可以各自耦合到多个漂移管段中的一个或多个。 控制电路被配置为以顺序地向漂移管段施加电场以允许具有预定离子迁移率或离子迁移率范围的离子行进穿过漂移管的方式来控制电场激活源的数量的操作。 漂移管段可以限定具有连续离子行进路径的线性漂移管或闭合漂移管。 公开了用于操作离子迁移谱仪以产生高度分辨的离子迁移率光谱的技术。

    Orthogonal ion injection apparatus and process
    4.
    发明授权
    Orthogonal ion injection apparatus and process 有权
    正交离子注入装置及工艺

    公开(公告)号：US08698075B2

    公开(公告)日：2014-04-15

    申请号：US13114869

    申请日：2011-05-24

    申请人： Ruwan T. Kurulugama ,  Mikhail E. Belov

    发明人： Ruwan T. Kurulugama ,  Mikhail E. Belov

    IPC分类号： H01J49/06

    CPC分类号： H01J49/065 ,  H01J49/0404 ,  H01J49/044

    摘要： An orthogonal ion injection apparatus and process are described in which ions are directly injected into an ion guide orthogonal to the ion guide axis through an inlet opening located on a side of the ion guide. The end of the heated capillary is placed inside the ion guide such that the ions are directly injected into DC and RF fields inside the ion guide, which efficiently confines ions inside the ion guide. Liquid droplets created by the ionization source that are carried through the capillary into the ion guide are removed from the ion guide by a strong directional gas flow through an inlet opening on the opposite side of the ion guide. Strong DC and RF fields divert ions into the ion guide. In-guide orthogonal injection yields a noise level that is a factor of 1.5 to 2 lower than conventional inline injection known in the art. Signal intensities for low m/z ions are greater compared to convention inline injection under the same processing conditions.

    摘要翻译： 描述了一种正交离子注入装置和方法，其中离子通过位于离子导向器一侧的入口直接注入垂直于离子引导轴的离子导向器中。 加热的毛细管的末端放置在离子导向器内，使得离子直接注入到离子导向器内的DC和RF场中，这有效地将离子限制在离子导向器内。 由电离源产生的通过毛细管进入离子导向器的液滴通过强力的定向气流从离子导向器的相反侧的入口开口从离子导向器移除。 强直流和射频场将离子转移到离子导向器中。 导向正交注入产生比现有技术中已知的常规在线注入低1.5至2倍的噪声电平。 在相同的处理条件下，与常规的直线注入相比，低m / z离子的信号强度更大。