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公开(公告)号：US08045152B2
公开(公告)日：2011-10-25
申请号：US11762430
申请日：2007-06-13
申请人： Nancy J. Halas , Don H. Johnson , Sandra Whaley Bishnoi , Carly S. Levin , Christopher John Rozell , Bruce R. Johnson
发明人： Nancy J. Halas , Don H. Johnson , Sandra Whaley Bishnoi , Carly S. Levin , Christopher John Rozell , Bruce R. Johnson
IPC分类号： G01J3/44
CPC分类号： G01N21/658 , G01N21/80
摘要： A composition comprising a nanoparticle and at least one adsorbate associated with the nanoparticle, wherein the adsorbate displays at least one chemically responsive optical property. A method comprising associating an adsorbate with a nanoparticle, wherein the nanoparticle comprises a shell surrounding a core material with a lower conductivity than the shell material and the adsorbate displays at least one chemically responsive optical property, and engineering the nanoparticle to enhance the optical property of the adsorbate. A method comprising determining an optical response of an adsorbate associated with a nanoparticle as a function of a chemical parameter, and parameterizing the optical response to produce a one-dimensional representation of at least a portion of a spectral window of the optical response in a high dimensional vector space.
摘要翻译： 一种组合物，其包含纳米颗粒和与所述纳米颗粒相关联的至少一种被吸附物，其中所述被吸附物显示出至少一种化学响应的光学性质。 一种包括使被吸附物与纳米颗粒缔合的方法，其中所述纳米颗粒包括围绕具有比所述壳材料更低导电性的核心材料的壳体，并且所述被吸附物显示出至少一种化学响应的光学性质，并且设计所述纳米颗粒以提高所述纳米颗粒的光学性质 被吸附物。 一种方法，包括根据化学参数确定与纳米颗粒相关联的被吸附物的光学响应，以及参数化所述光学响应以产生光响应的光谱窗口的至少一部分的高维度的一维表示 三维向量空间。
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公开(公告)号：US20080176212A1
公开(公告)日：2008-07-24
申请号：US11762430
申请日：2007-06-13
申请人： Nancy J. Halas , Don H. Johnson , Sandra Whaley Bishnoi , Carly S. Levin , Christopher John Rozell , Bruce R. Johnson
发明人： Nancy J. Halas , Don H. Johnson , Sandra Whaley Bishnoi , Carly S. Levin , Christopher John Rozell , Bruce R. Johnson
CPC分类号： G01N21/658 , G01N21/80
摘要： A composition comprising a nanoparticle and at least one adsorbate associated with the nanoparticle, wherein the adsorbate displays at least one chemically responsive optical property. A method comprising associating an adsorbate with a nanoparticle, wherein the nanoparticle comprises a shell surrounding a core material with a lower conductivity than the shell material and the adsorbate displays at least one chemically responsive optical property, and engineering the nanoparticle to enhance the optical property of the adsorbate. A method comprising determining an optical response of an adsorbate associated with a nanoparticle as a function of a chemical parameter, and parameterizing the optical response to produce a one-dimensional representation of at least a portion of a spectral window of the optical response in a high dimensional vector space.
摘要翻译： 一种组合物，其包含纳米颗粒和与所述纳米颗粒相关联的至少一种被吸附物，其中所述被吸附物显示出至少一种化学响应的光学性质。 一种包括使被吸附物与纳米颗粒缔合的方法，其中所述纳米颗粒包括围绕具有比所述壳材料更低导电性的核心材料的壳体，并且所述被吸附物显示出至少一种化学响应的光学性质，并且设计所述纳米颗粒以提高所述纳米颗粒的光学性质 被吸附物。 一种方法，包括根据化学参数确定与纳米颗粒相关联的被吸附物的光学响应，以及参数化所述光学响应以产生光响应的光谱窗口的至少一部分的高维 三维向量空间。
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公开(公告)号：US20050069949A1
公开(公告)日：2005-03-31
申请号：US10605430
申请日：2003-09-30
IPC分类号： B01L3/00 , C40B60/14 , G01N33/53 , G01N33/543
CPC分类号： G01N33/5304 , B01J2219/00317 , B01J2219/00319 , B01J2219/00364 , B01L3/5025 , B01L3/502715 , B01L3/50857 , B01L2300/0819 , B01L2400/0406 , B01L2400/0418 , B01L2400/0421 , B01L2400/0457 , B01L2400/0487 , B01L2400/0688 , B01L2400/086 , C40B60/14
摘要： A plate for use in mixing and testing materials in the pharmaceutical industry is formed by a method in which an array of sample cells contain a U-shaped structure having two vertical apertures connected by a horizontal passage in a bottom sheet; reagents are drawn in to the vertical passages by capillary action or other forces and react in the horizontal passage. An optional version of the invention includes a relatively large reservoir for containing rinsing fluids.
摘要翻译： 用于制药工业中混合和测试材料的板材通过一种方法形成，其中样品池的阵列包含具有通过底片中的水平通道连接的两个垂直孔的U形结构; 试剂通过毛细管作用或其他力吸入垂直通道，并在水平通道中反应。 本发明的可选版本包括用于容纳冲洗液体的相对较大的储存器。
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公开(公告)号：US20050069462A1
公开(公告)日：2005-03-31
申请号：US10605429
申请日：2003-09-30
CPC分类号： B01L9/527 , B01L3/5025 , B01L3/502707 , B01L3/50857 , B01L2200/025 , B01L2300/0887
摘要： A plate for use in mixing and testing materials in the pharmaceutical industry is formed by a method in which an array of sample cells contain a U-shaped structure having two vertical apertures connected by a horizontal passage in a bottom sheet; reagents are drawn in to the vertical passages by capillary action and react in the horizontal passage. An optional version of the invention includes a relatively large reservoir for containing rinsing fluids.
摘要翻译： 用于制药工业中混合和测试材料的板材通过一种方法形成，其中样品池的阵列包含具有通过底片中的水平通道连接的两个垂直孔的U形结构; 试剂通过毛细作用吸入垂直通道，并在水平通道中反应。 本发明的可选版本包括用于容纳冲洗液体的相对较大的储存器。
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