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1.发明公开公开(公告)号：US20240009078A1
公开(公告)日：2024-01-11
申请号：US18348450
申请日：2023-07-07
摘要： A glass container is characterized by a longitudinal axis (Ltube) that passes through a center of a glass bottom of the glass container. For any cut surface of the glass container that is obtainable by cutting the glass container in a plane that includes the longitudinal axis Ltube, a minimum thickness (smin) and a maximum thickness (smax) of the glass bottom determined at any position having a distance d1/4 or less to the longitudinal axis Ltube and a thickness (sd1/4) is the thickness of the glass bottom determined at a position having the distance d1/4 to the longitudinal axis Ltube, the distance to the longitudinal axis Ltube in each case being determined in a direction that is perpendicular to the longitudinal axis Ltube and thicknesses smin, smax and sd1/4 being determined in a direction that is parallel to longitudinal axis Ltube, with smax/smin being less than 1.8.
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公开(公告)号：US11613396B2
公开(公告)日：2023-03-28
申请号：US16920793
申请日：2020-07-06
发明人： Andreas Langsdorf , Florian Maurer , Peter Thomas , Alexander Humbertjean , Tobias Wetzel , Hanspeter Kummer
摘要： A glass container is provided having a glass tube with a first end and a second end and a glass bottom closing the second end. The glass tube has a longitudinal axis and has, in a direction from the first to the second end, a top region, a junction region, a neck region, a shoulder region, and a body region. The top region is at the first end and has an outer diameter (dt), the neck region has an outer diameter (dn) with dn dt, and the glass tube in the body region has a thickness (lb). The outer contour in a transition area between the top and neck regions is defined by a radius of curvature. The glass containers have a neck squeeze test load of at least 1100 N.
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3.发明公开公开(公告)号：US20240131815A1
公开(公告)日：2024-04-25
申请号：US18404784
申请日：2024-01-04
IPC分类号： B32B5/02
CPC分类号： B32B5/022 , B32B2307/724 , B32B2307/7265
摘要： Disclosed are films and a packaging for gas or vapor decontaminable packaging applications and a method for creating a sterile packaging using the same. These films are particularly useful for sterile storage and transport of objects for medical, pharmaceutical or cosmetic uses, in particular of sterile pharmaceutical primary packaging means, like vials, ampules, syringes, or cartridges. Said film comprises at least a layer of a selectively permeable non-woven, a layer of a punctured film, and an adhesive which can be activated by energy transmission. Optionally it comprises further film layers. The method for creating a sterile packaging comprises the step of hermetically closing the packaging by activating the adhesive thereby making the non-woven impermeable.
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公开(公告)号：US11964135B2
公开(公告)日：2024-04-23
申请号：US17193395
申请日：2021-03-05
发明人： Raymond Moser , Stephanie Mangold
CPC分类号： A61M5/3129 , A61M5/31505 , A61M2005/3103 , A61M2005/3131 , A61M2205/0222 , A61M2207/00
摘要： A receptacle includes an elongate barrel section defining a barrel length between an axial position pA and an axial position pB; side walls each having an inner surface bordering an interior; a layer of a lubricant located on the inner surface; and a charge present in the interior and sealing a cross section of the interior between the inner surfaces of the side walls. An axial position p+ is the axial position closest to pB at which the charge contacts the layer or the inner surfaces and an axial position p− is the axial position closest to pA at which the charge contacts the layer or the inner surfaces. The distance between pB and p+ divided by the distance between p+ and pA is in a range from 0 to 2 and a mean thickness of the layer between pA and p. is at least 10 nm.
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公开(公告)号：US20240009080A1
公开(公告)日：2024-01-11
申请号：US18471763
申请日：2023-09-21
发明人： Matthias Bicker , Christoph Brüning , Anne Spende , Flor Toledo Rodríguez , Michaela Klause , Uwe Rothhaar , Tanja Woywod , Eveline Rudigier-Voigt , Jovana Djordjevic-Reiss , Sylvia Biedenbender , Harmut Bauch
IPC分类号： A61J1/14
CPC分类号： A61J1/1468
摘要： A pharmaceutical container includes an inner surface and an outer surface. At least part of the inner surface is coated with a coating to form a coated inner surface. On the coated inner surface the container, based on negative mode Time-of-Flight-Secondary Ion Mass Spectrometry (ToF-SIMS) data, has a relative lipid nanoparticle (LNP)-incubated Multivariate Curve Resolution (MCR) score ratio of lipid factor1 of less than 0.67.
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公开(公告)号：US11633542B2
公开(公告)日：2023-04-25
申请号：US16816720
申请日：2020-03-12
发明人： Elmar Horsch , Tanja Woywod
摘要： A pharmaceutical container for drug delivery includes a barrel configured to slidably receive a stopper. The stopper has a proximal end suitable for contacting a plunger rod and a distal end suitable for contacting a pharmaceutical composition. The stopper has a circumferential surface partially contacting an inner surface of the barrel. A surface roughness of the inner surface of the barrel declines from the stopper's start position to its end position by at least 3% of at least one of Ra roughness or Rms roughness.
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公开(公告)号：US20240009079A1
公开(公告)日：2024-01-11
申请号：US18348464
申请日：2023-07-07
发明人： Andreas Langsdorf , Florian Maurer , Lucia Dessoy , Ina Syndikus , Alexander Humbertjean , Tobias Wetzel , Fatih Mutlu
CPC分类号： A61J1/1468 , B65D1/0207 , A61J1/1412
摘要： A glass container includes a body region with a first end and a second end, the body region having an outer diameter (d1) and a glass thickness (s1), the body region being characterized by a longitudinal axis (Ltube) that passes through a center of the first and second end. When the glass container is standing on a support surface, h2 is the distance between the support surface up to the second end of the body region. The following condition is fulfilled: (A×X)/B=C. A is an axial load necessary to break the glass container to obtain fragments, X is a normalized area in cm2 defined as h2×d1×π+d12/4×π, B is a number of fragments of the glass container, and C is a fracture ratio. C is 40 N×cm2 or more and B is 30 or more.
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公开(公告)号：US11801348B2
公开(公告)日：2023-10-31
申请号：US16991104
申请日：2020-08-12
CPC分类号： A61M5/3129 , A61M5/315 , A61J1/065
摘要： A glass syringe barrel is provided that has an at least partially conically shaped upper portion and a longitudinal axis. The glass syringe barrel has a top end through which a liquid can be ejected and a bottom end into which a plunger stopper can be pushed. The glass syringe barrel includes, in a direction from the top end to the bottom end, a cone, a shoulder region, and a body region. The shoulder region has and outer contour that has a concave and substantially circular arc-shaped area c1 with an outer radius r1. The outer contour of the glass syringe barrel in the shoulder region is defined by a certain minimum value the radius of curvature.
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公开(公告)号：US11746034B2
公开(公告)日：2023-09-05
申请号：US16938271
申请日：2020-07-24
发明人： Diego Studerus , Oliver Fruhner , Andreas Groh
IPC分类号： C03B23/11 , C03B23/045 , C03B23/09
CPC分类号： C03B23/112 , C03B23/045 , C03B23/09
摘要： A hot forming device for producing glass containers from a glass tube is provided. The device includes a machine frame, a turntable, a plurality of holding chucks, and a direct drive motor. The turntable is mounted on the machine frame. The holding chucks are arranged on the turntable. The turntable is connected to the machine frame directly by the direct drive without a transmission. The direct drive has a stator arranged in an upper region of the machine frame and a rotor on the turntable.
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公开(公告)号：US11707412B2
公开(公告)日：2023-07-25
申请号：US16992798
申请日：2020-08-13
发明人： Robert Frost , Uwe Rothhaar , Florence Buscke , Bernhard Hladik
CPC分类号： A61J1/1468 , A61J1/065 , C03B9/335 , C03C3/089
摘要： A glass vial includes a base including a boron-containing multicomponent glass and a vial opening and holds a liquid active pharmaceutical ingredient formulation. The glass vial has a total volume of
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