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公开(公告)号：US5674736A
公开(公告)日：1997-10-07
申请号：US486719
申请日：1995-06-07
IPC分类号： A61K39/00 , A61K39/02 , A61K39/112 , A61P31/04 , C07K14/255 , C12N1/21 , C12N15/01 , C12N15/09 , C12N15/74 , C12Q1/68 , C12R1/01 , C12R1/42 , C12N1/20 , C12N1/36
CPC分类号： C12R1/42 , A61K39/0275 , C07K14/255 , C12N15/01 , C12N15/74 , A61K2039/522 , A61K39/00
摘要： A vector capable of integrating into the chromosome of Salmonella including a first DNA sequence encoding a heterologous protein, a second DNA sequence encoding a marker, and a third DNA sequence encoding a phoP regulatory region regulated gene product necessary for virulence, the third DNA sequence being mutationally inactivated
摘要翻译： 能够整合入沙门氏菌染色体的载体，包括编码异源蛋白质的第一DNA序列，编码标志物的第二DNA序列和编码毒力所必需的phoP调节区域调节基因产物的第三DNA序列，第三DNA序列为 突变失活
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公开(公告)号：US5674724A
公开(公告)日：1997-10-07
申请号：US486715
申请日：1995-06-07
IPC分类号： A61K39/00 , A61K39/02 , A61K39/112 , A61P31/04 , C07K14/255 , C12N1/21 , C12N15/01 , C12N15/09 , C12N15/74 , C12Q1/68 , C12R1/01 , C12R1/42 , C12N1/36 , C12N1/20 , C12P21/02
CPC分类号： C12R1/42 , A61K39/0275 , C07K14/255 , C12N15/01 , C12N15/74 , A61K2039/522 , A61K39/00
摘要： A vector capable of integrating into the chromosome of Salmonella including a first DNA sequence encoding a heterologous protein, a second DNA sequence encoding a marker, and a third DNA sequence encoding a phoP regulatory region regulated gene product necessary for virulence, the third DNA sequence being mutationally inactivated.
摘要翻译： 能够整合入沙门氏菌染色体的载体，包括编码异源蛋白质的第一DNA序列，编码标志物的第二DNA序列和编码毒力所必需的phoP调节区域调节基因产物的第三DNA序列，第三DNA序列为 突变失活
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公开(公告)号：US6010901A
公开(公告)日：2000-01-04
申请号：US475749
申请日：1995-06-07
IPC分类号： A61K39/00 , A61K39/02 , A61K39/112 , A61P31/04 , C07K14/255 , C12N1/21 , C12N15/01 , C12N15/09 , C12N15/74 , C12Q1/68 , C12R1/01 , C12R1/42 , C07H21/04
CPC分类号： C12R1/42 , A61K39/0275 , C07K14/255 , C12N15/01 , C12N15/74 , A61K2039/522 , A61K39/00
摘要： A vector capable of integrating into the chromosome of Salmonella including a first DNA sequence encoding a heterologous protein, a second DNA sequence encoding a marker, and a third DNA sequence encoding a phoP regulatory region regulated gene product necessary for virulence, the third DNA sequence being mutationally inactivated.
摘要翻译： 能够整合入沙门氏菌染色体的载体，包括编码异源蛋白质的第一DNA序列，编码标志物的第二DNA序列和编码毒力所必需的phoP调节区域调节基因产物的第三DNA序列，第三DNA序列为 突变失活
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公开(公告)号：US5731196A
公开(公告)日：1998-03-24
申请号：US476100
申请日：1995-10-06
IPC分类号： A61K39/00 , A61K39/02 , A61K39/112 , A61P31/04 , C07K14/255 , C12N1/21 , C12N15/01 , C12N15/09 , C12N15/74 , C12Q1/68 , C12R1/01 , C12R1/42 , C12N15/31 , C12N15/63
CPC分类号： C12R1/42 , A61K39/0275 , C07K14/255 , C12N15/01 , C12N15/74 , A61K2039/522 , A61K39/00
摘要： A vector capable of integrating into the chromosome of Salmonella including a first DNA sequence encoding a heterologous protein, a second DNA sequence encoding a marker, and a third DNA sequence encoding a phoP regulatory region regulated gene product necessary for virulence, the third DNA sequence being mutationally inactivated
摘要翻译： 能够整合入沙门氏菌染色体的载体，包括编码异源蛋白质的第一DNA序列，编码标志物的第二DNA序列和编码毒力所必需的phoP调节区域调节基因产物的第三DNA序列，第三DNA序列为 突变失活
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公开(公告)号：US5599537A
公开(公告)日：1997-02-04
申请号：US90526
申请日：1993-07-09
IPC分类号： A61K39/00 , A61K39/02 , A61K39/112 , A61P31/04 , C07K14/255 , C12N1/21 , C12N15/01 , C12N15/09 , C12N15/74 , C12Q1/68 , C12R1/01 , C12R1/42 , C12N1/20
CPC分类号： C12R1/42 , A61K39/0275 , C07K14/255 , C12N15/01 , C12N15/74 , A61K2039/522 , A61K39/00
摘要： A vector capable of integrating into the chromosome of Salmonella including a first DNA sequence encoding a heterologous protein, a second DNA sequence encoding a marker, and a third DNA sequence encoding a phoP regulatory region regulated gene product necessary for virulence, the third DNA sequence being mutationally inactivated.
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