公开(公告)号：US4556563A

公开(公告)日：1985-12-03

申请号：US474750

申请日：1983-03-10

申请人： Marianna Pongor nee Csakvari ,  Gabor Nagy ,  Gabor Horvath ,  Maria David nee Kenez ,  Sandor Bozsoky ,  Sandor Virag ,  Katalin Marmarosi nee Kellner

发明人： Marianna Pongor nee Csakvari ,  Gabor Nagy ,  Gabor Horvath ,  Maria David nee Kenez ,  Sandor Bozsoky ,  Sandor Virag ,  Katalin Marmarosi nee Kellner

IPC分类号： A61K31/40 ,  A61K31/505 ,  A61P29/00 ,  A61K31/60

CPC分类号： A61K31/505 ,  Y10S514/96 ,  Y10S514/966

摘要： The invention relates to synergistic antiphlogistic pharmaceutical compositions comprising a pyrido [1,2-a]-pyrimidine derivative of the Formula I ##STR1## wherein R.sup.1 and R.sup.2 are lower alkyl and R.sup.3 stands for lower alkoxycarbonyl or carbamoyl and the dotted line represents an optionally hydrogenated band or a salt or quaternary salt thereof and 1-[p-chloro-benzoly]-2-methyl-5-methoxy-indolyl-3-acetic acid of the Formula II ##STR2## The advantage of the compositions is that as a result of the synergistic activity of the compound of the Formula I, the antiphlogistic Indomethacin of the Formula II can be administered in a significantly lower doses and consequently the unfavorable side effects of the latter compound are mitigated.

摘要翻译： 本发明涉及包含式I的吡啶并[1,2-a] - 嘧啶衍生物（I）的协同消炎药物组合物，其中R1和R2是低级烷基，R3代表低级烷氧基羰基或氨基甲酰基，虚线 代表任选氢化的带或其盐或季盐和式II的1- [对氯 - 苯并[2-氯苯基] -2-甲基-5-甲氧基 - 吲哚基-3-乙酸。（II） 组合物是由于式I化合物的协同作用的结果，可以以显着较低的剂量施用式II的消炎药吲哚美辛，从而减轻后一种化合物的不良副作用。

公开(公告)号：US4485825A

公开(公告)日：1984-12-04

申请号：US402339

申请日：1982-07-27

申请人： Laszlo Domjan ,  Geza Balint ,  Sandor Bozsoky

发明人： Laszlo Domjan ,  Geza Balint ,  Sandor Bozsoky

IPC分类号： A61B5/103 ,  G01B3/56 ,  G01B5/207 ,  A61B5/08

CPC分类号： A61B5/4528 ,  A61B5/1071 ,  A61B5/1116 ,  A61B5/4561 ,  G01B3/563 ,  G01B5/207 ,  A61B5/4504 ,  A61B5/6814 ,  A61B5/6823 ,  A61B5/6828 ,  A61B5/6831

摘要： An instrument for measuring positions and displacements of portions of a human body, comprising a base plate and a belt or suction cup for detachably securing the base plate to a portion of a human body. A bifurcated holder is mounted on the base plate for rotation about a first axis, the bifurcated holder having a pair of arms, and a housing is pivotally carried between these arms for swinging movement about a second axis perpendicular to the first axis. A dip circle and a north-south-seeking compass are carried by this housing, the dip circle and compass being mounted on the housing for pivotal movement about a common third axis perpendicular to the second axis. The base plate has a scale thereon, and there is an indicator on the holder for indicating on the scale the degree of rotation of the holder relative to the base plate. There is also a scale for indicating the degree of rotation of the dip circle and compass relative to the housing, and this scale is rotatable relative to the housing about that common third axis.

摘要翻译： 一种用于测量人体部分的位置和位移的仪器，包括基板和用于将基板可拆卸地固定到人体的一部分的皮带或吸盘的位置。 分叉保持器安装在基板上用于围绕第一轴线旋转，分叉保持器具有一对臂，并且壳体枢转地承载在这些臂之间，用于围绕垂直于第一轴线的第二轴线摆动。 倾斜圆圈和南北寻常的罗盘由该壳体承载，倾角圆和罗盘安装在壳体上以围绕垂直于第二轴线的公共第三轴线枢转运动。 基板上有刻度，并且在支架上有指示器，用于在刻度上指示保持器相对于基板的旋转程度。 还有一个用于指示倾斜圆圈和罗盘相对于壳体的旋转程度的刻度，并且该刻度尺围绕该公共第三轴线相对于壳体可旋转。