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公开(公告)号:US09034883B2
公开(公告)日:2015-05-19
申请号:US13295174
申请日:2011-11-14
申请人: Thomas Klein , Andreas Daiber , Odd-Eric Johansen , Michael Mark , Sanjaykumar Patel , Hans-Juergen Woerle
发明人: Thomas Klein , Andreas Daiber , Odd-Eric Johansen , Michael Mark , Sanjaykumar Patel , Hans-Juergen Woerle
IPC分类号: A61K31/52 , C07D473/12 , A61K31/519 , C07D473/06 , A61K31/397 , A61K31/522 , A61K31/5377 , A61K31/616 , A61K31/727 , A61K31/785 , A61K38/26 , A61K38/28 , A61K45/06
CPC分类号: A61K31/522 , A61K31/155 , A61K31/397 , A61K31/4184 , A61K31/519 , A61K31/5377 , A61K31/616 , A61K31/727 , A61K31/785 , A61K38/26 , A61K38/28 , A61K45/06 , C07D473/06 , C07D473/12 , A61K2300/00
摘要: The present invention relates to certain DPP-4 inhibitors for treating and/or preventing oxidative stress, vascular stress and/or endothelial dysfunction as well as to the use of such DPP-4 inhibitors in treatment and/or prevention of diabetic or non-diabetic patients, including patient groups at risk of cardiovascular and/or renal disease.
摘要翻译: 本发明涉及用于治疗和/或预防氧化应激,血管应激和/或内皮功能障碍的某些DPP-4抑制剂以及这种DPP-4抑制剂在治疗和/或预防糖尿病或非糖尿病中的用途 包括患有心血管和/或肾脏疾病风险的患者群体。
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公开(公告)号:US20120121530A1
公开(公告)日:2012-05-17
申请号:US13295174
申请日:2011-11-14
申请人: Thomas KLEIN , Andreas DAIBER , Odd-Eric JOHANSEN , Michael MARK , Sanjaykumar PATEL , Hans-Juergen WOERLE
发明人: Thomas KLEIN , Andreas DAIBER , Odd-Eric JOHANSEN , Michael MARK , Sanjaykumar PATEL , Hans-Juergen WOERLE
IPC分类号: A61K31/522 , A61K38/26 , A61K31/397 , A61K31/616 , A61K31/727 , A61K31/519 , A61K31/5377 , A61K31/785 , A61P9/00 , A61P39/06 , A61P3/10 , A61P3/08 , A61P3/04 , A61P3/06 , A61P9/12 , A61P9/10 , A61P19/10 , A61P29/00 , A61P1/16 , A61P27/02 , A61P25/00 , A61P13/12 , A61P15/00 , A61P3/00 , A61P27/12 , A61P25/28 , A61P9/04 , A61P9/06 , A61P1/18 , A61K38/28
CPC分类号: A61K31/522 , A61K31/155 , A61K31/397 , A61K31/4184 , A61K31/519 , A61K31/5377 , A61K31/616 , A61K31/727 , A61K31/785 , A61K38/26 , A61K38/28 , A61K45/06 , C07D473/06 , C07D473/12 , A61K2300/00
摘要: The present invention relates to certain DPP-4 inhibitors for treating and/or preventing oxidative stress, vascular stress and/or endothelial dysfunction as well as to the use of such DPP-4 inhibitors in treatment and/or prevention of diabetic or non-diabetic patients, including patient groups at risk of cardiovascular and/or renal disease.
摘要翻译: 本发明涉及用于治疗和/或预防氧化应激,血管应激和/或内皮功能障碍的某些DPP-4抑制剂以及这种DPP-4抑制剂在治疗和/或预防糖尿病或非糖尿病中的用途 包括患有心血管和/或肾脏疾病风险的患者群体。
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