摘要:
A method for manufacturing a drug-delivery composition includes providing at least one pharmaceutically active compound, a dry powder comprising at least a polymer, and an aqueous solution. The dry powder, the pharmaceutically active compound and the aqueous solution are mixed to form a paste-like or semi-solid drug-delivery composition, wherein the aqueous solution is added in an amount of less than or equal to twice the total dry mass of the dry powder.
摘要:
An implant for intraocular drug delivery for the treatment of inflammatory or degenerative diseases. In one embodiment, the implant includes a body portion having a first end portion and a second, opposite end portion and defining a cavity with a first opening at the first end portion, and a second, opposite opening at the second end portion, and a solid material received in the cavity, wherein the solid material comprises a depot material and an effective amount of at least one therapeutic compound or agent. When the implant is implanted in an eye of a living subject, the effective amount of at least one therapeutic compound or agent is released to the environment of the implant through at least one of the first opening and the second, opposite opening over an extended period of time.
摘要:
An implant for intraocular drug delivery for the treatment of inflammatory or degenerative diseases. In one embodiment, the implant includes a body portion having a first end portion and a second, opposite end portion and defining a cavity with a first opening at the first end portion, and a second, opposite opening at the second end portion, and a solid material received in the cavity, wherein the solid material comprises a depot material and an effective amount of at least one therapeutic compound or agent. When the implant is implanted in an eye of a living subject, the effective amount of at least one therapeutic compound or agent is released to the environment of the implant through at least one of the first opening and the second, opposite opening over an extended period of time.
摘要:
A separator that includes a body and a leading edge portion. The leading edge portion includes an upper planar surface oriented at an angle ranging from approximately 40° to 90° relative to a horizontal plane and a lower planar surface oriented at an angle ranging from approximately 0° to 30° relative to the horizontal plane, wherein the upper planar surface and the lower planar surface intersect one another so as to define a blunt leading edge and the leading edge portion is made of a material that has a hardness so as to separate an epithelial layer of an eye from an cornea stroma of said eye without substantially damaging said epithelial layer and wherein said blunt leading edge is incapable of cutting said stroma.
摘要:
A practice ball can comprise a coating on a plastic substantially spherical core having a solid continuous outer surface and a hollow interior. Raised laces features can extend from the outer surface of the core. The coating can also disposed on the raised laces features, and a portion of the coating on the raised laces features can extend from an outer surface of the coating on the outer surface of the core.
摘要:
A method for manufacturing a drug-delivery composition includes providing at least a pharmaceutically active composition, providing a hydrophobic matrix; and mixing the hydrophobic matrix and the pharmaceutically active composition to form a paste-like or semi-solid drug-delivery composition.
摘要:
A valve and connector assembly for interconnection with and rinsing of sewage hoses including sewage discharge hoses and connectors for Recreational Vehicles. The assembly comprises a connector for interconnection with a sewage hose having connectors compatible with a RV sewage discharge valve. The assembly has a garden hose connector to receive a garden hose hookup to direct water into the contaminated sewage hose for rinsing prior to storage of the sewage hose. A diffuser within the connector causes the water stream to spray thereby rinsing the sewage hose.
摘要:
The disclosure concerns a scleral expansion segment of the type consisting of an arched rod designed to be placed on the sclera perpendicular to the ciliary body. The free ends of said rod have a spatula shape wider than the diameter of said bridge, so as to constitute wide support bases.
摘要:
A device to provide hyperspectral reflection spectrum, hyperspectral depolarization, and hyperspectral fluorescence spectrum data in a portable, remote sensing instrument. The device can provide a large range of remotely-sensed optical property data, presently only obtainable in laboratories, in a low-cost field instrument. Among its many uses, the present invention can be used by farmers as a tool for determining the nitrogen content of crops to optimize fertilizer laydown.
摘要:
A contamination detection apparatus is provided for measuring an amount of contamination on an optically transmitting element or pane. The optically transmitting element is capable of transmitting electromagnetic radiation. The contamination detection apparatus includes a contamination detection (CD) radiation source for providing a source intensity of radiation. The source intensity or radiation passes through the optically transmitting element at least one time. A reference detector is also provided for detecting the source intensity of radiation, and the reference detector has a reference output level that is representative of the source intensity.