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公开(公告)号:US20060057587A1
公开(公告)日:2006-03-16
申请号:US10939650
申请日:2004-09-13
申请人: Scott Vacha , Eric Leproust
发明人: Scott Vacha , Eric Leproust
CPC分类号: C12Q1/6837 , C12Q2545/101 , C12Q2525/161
摘要: The invention relates to chemical arrays comprising a plurality of features comprising biopolymers at known locations on the substrate, wherein at least one feature comprises specific hybridization probes designed or selected to bind to specific target sequences and background probes for evaluating non-specific binding of target. Methods, systems, and kits for making and using the arrays are also described.
摘要翻译: 本发明涉及包含多个特征的化学阵列,其包含在底物上已知位置处的生物聚合物,其中至少一个特征包括设计或选择以结合特异性靶序列的特异性杂交探针和用于评估靶的非特异性结合的背景探针。 还描述了用于制造和使用阵列的方法,系统和套件。