公开(公告)号：US06924273B2

公开(公告)日：2005-08-02

申请号：US09967977

申请日：2001-10-02

申请人： Scott W. Pierce

发明人： Scott W. Pierce

IPC分类号： A23K1/18 ,  A61K31/7008 ,  A61K31/728 ,  A01N65/00 ,  A61K38/16 ,  A61K31/73

CPC分类号： A61K31/728 ,  A23K50/20 ,  A61K31/7008 ,  A61K2300/00

摘要： The instant invention provides a method of treating or preventing osteoarthritis, joint effusion, joint inflammation and pain, synovitis, lameness, post operative arthroscopic surgery, deterioration of proper joint function including joint mobility, the reduction or inhibition of metabolic activity of chondrocytes, the activity of enzymes that degrade cartilage, the reduction or inhibition of the production of Hyaluronic acid, said method comprising orally administering to a mammalian species a therapeutically effective amount of Hyaluronic Acid or pharmaceutically acceptable salts thereof. Additionally, compositions containing hyaluronic acid; chondroitin sulfate, and glucosamine sulfate in a paste formulation are also disclosed which can be administered on their own or can be used as a feed additive.

摘要翻译： 本发明提供了治疗或预防骨关节炎，关节积液，关节炎症和疼痛，滑膜炎，跛行，术后关节镜手术，适当关节功能恶化（包括关节活动性），减少或抑制软骨细胞代谢活性的方法 的降解软骨的酶，减少或抑制透明质酸的产生，所述方法包括向哺乳动物物种口服施用治疗有效量的透明质酸或其药学上可接受的盐。 另外，含有透明质酸的组合物; 还公开了一种糊剂制剂中的硫酸软骨素和硫酸葡萄糖胺，其可以单独施用或可以用作饲料添加剂。