公开(公告)号：US20090275996A1

公开(公告)日：2009-11-05

申请号：US12433770

申请日：2009-04-30

申请人： John E. Burnes ,  Eduardo N. Warman ,  Matthew D. Bonner ,  Avram Scheiner ,  Shailesh Kumar V. Musley

发明人： John E. Burnes ,  Eduardo N. Warman ,  Matthew D. Bonner ,  Avram Scheiner ,  Shailesh Kumar V. Musley

IPC分类号： A61N1/36

CPC分类号： A61N1/36053 ,  A61M25/09 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/0558 ,  A61N1/057 ,  A61N1/36085 ,  A61N1/36114 ,  A61N1/36125 ,  A61N1/36128

摘要： This disclosure is directed to extra, intra, and transvascular medical lead placement techniques for arranging medical leads and electrical stimulation and/or sensing electrodes proximate nerve tissue within a patient.

摘要翻译： 本公开涉及用于在患者体内靠近神经组织布置医疗引线和电刺激和/或感测电极的额外的，内部的和经血管内的医疗引线放置技术。

公开(公告)号：US20100286541A1

公开(公告)日：2010-11-11

申请号：US12463470

申请日：2009-05-11

申请人： Shailesh Kumar V. Musley ,  Vincent E. Splett ,  Aleksandre T. Sambelashvili

发明人： Shailesh Kumar V. Musley ,  Vincent E. Splett ,  Aleksandre T. Sambelashvili

IPC分类号： A61B5/0452

CPC分类号： A61B5/0452 ,  A61B5/02405 ,  A61B5/726 ,  A61N1/3702

摘要： Techniques are described for detecting conduction abnormalities in a heart of a patient. In particular, an IMD may be configured to obtain electrical signals corresponding to cardiac activity of the heart of the patient and periodically analyze a most recent electrical signal of the obtained electrical signals to detect an electrical conduction abnormality of the heart. The IMD adjusts a frequency at which the most recent electrical signal is analyzed based on at least one physiological parameter of the patient. For example, the IMD may increase the frequency at which the most recent electrical signal is analyzed when a heart rate parameter has significantly changed and the number of detected premature ventricular contractions (PVCs) is greater than or equal to a threshold number. In this manner, the most recent electrical signal is analyzed at a higher frequency in situations in which conduction abnormalities are more likely.

摘要翻译： 描述了用于检测患者心脏中的传导异常的技术。 特别地，可以将IMD配置为获得对应于患者心脏的心脏活动的电信号，并且周期性地分析所获得的电信号的最新电信号以检测心脏的电传导异常。 IMD基于患者的至少一个生理参数来调整分析最近的电信号的频率。 例如，当心率参数已经显着改变并且检测到的早产性心室收缩（PVC）的数量大于或等于阈值数量时，IMD可以增加最近的电信号被分析的频率。 以这种方式，在导电异常更可能的情况下，以更高的频率分析最新的电信号。

公开(公告)号：US08391964B2

公开(公告)日：2013-03-05

申请号：US12463470

申请日：2009-05-11

申请人： Shailesh Kumar V. Musley ,  Vincent E. Splett ,  Aleksandre T. Sambelashvili

发明人： Shailesh Kumar V. Musley ,  Vincent E. Splett ,  Aleksandre T. Sambelashvili

IPC分类号： A61B5/04

CPC分类号： A61B5/0452 ,  A61B5/02405 ,  A61B5/726 ,  A61N1/3702

摘要： Techniques are described for detecting conduction abnormalities in a heart of a patient. In particular, an IMD may be configured to obtain electrical signals corresponding to cardiac activity of the heart of the patient and periodically analyze a most recent electrical signal of the obtained electrical signals to detect an electrical conduction abnormality of the heart. The IMD adjusts a frequency at which the most recent electrical signal is analyzed based on at least one physiological parameter of the patient. For example, the IMD may increase the frequency at which the most recent electrical signal is analyzed when a heart rate parameter has significantly changed and the number of detected premature ventricular contractions (PVCs) is greater than or equal to a threshold number. In this manner, the most recent electrical signal is analyzed at a higher frequency in situations in which conduction abnormalities are more likely.

摘要翻译： 描述了用于检测患者心脏中的传导异常的技术。 特别地，可以将IMD配置为获得对应于患者心脏的心脏活动的电信号，并且周期性地分析所获得的电信号的最新电信号以检测心脏的电传导异常。 IMD基于患者的至少一个生理参数来调整分析最近的电信号的频率。 例如，当心率参数已经显着改变并且检测到的早产性心室收缩（PVC）的数量大于或等于阈值数量时，IMD可以增加最近的电信号被分析的频率。 以这种方式，在导电异常更可能的情况下，以更高的频率分析最新的电信号。

公开(公告)号：US07336994B2

公开(公告)日：2008-02-26

申请号：US10760155

申请日：2004-01-16

申请人： Douglas A. Hettrick ,  David E. Euler ,  Eduardo N. Warman ,  Michael R. Ujhelyi ,  Rahul Mehra ,  Paul D. Ziegler ,  Shailesh Kumar V. Musley ,  Charles E. Distad ,  David E. Ritscher

发明人： Douglas A. Hettrick ,  David E. Euler ,  Eduardo N. Warman ,  Michael R. Ujhelyi ,  Rahul Mehra ,  Paul D. Ziegler ,  Shailesh Kumar V. Musley ,  Charles E. Distad ,  David E. Ritscher

IPC分类号： A61N1/39

CPC分类号： A61N1/3702 ,  A61N1/3621 ,  A61N1/365 ,  A61N1/36564 ,  A61N1/395 ,  A61N1/3962

摘要： Control of defibrillation therapy delivered by implantable medical devices (IMDs) using hemodynamic sensor feedback is disclosed. The hemodynamic sensor feedback allows for increased control over application of atrial defibrillation therapy. Specifically, the therapy is delivered when a fibrillation episode results in a discrete loss of hemodynamic function. Defibrillation therapy is thus withheld for hemodynamically benign arrhythmias.

摘要翻译： 公开了使用血液动力学传感器反馈控制由可植入医疗装置（IMD）递送的除颤疗法。 血液动力学传感器反馈允许增加对心房除颤治疗的应用的控制。 具体来说，当纤维性颤动发作导致血液动力学功能的离散损失时，进行治疗。 因此，对于血液动力学良性心律失常，禁止使用除颤疗法。