公开(公告)号：US06197540B1

公开(公告)日：2001-03-06

申请号：US08578591

申请日：1996-06-21

申请人： Vivian Granger ,  David Barnett ,  John T. Reilly ,  Petra S. M. Mayr ,  Shawn P. Fay

发明人： Vivian Granger ,  David Barnett ,  John T. Reilly ,  Petra S. M. Mayr ,  Shawn P. Fay

IPC分类号： A61K944

CPC分类号： G01N33/50 ,  G01N33/5002 ,  G01N33/5094 ,  G01N33/56972 ,  G01N33/56977 ,  G01N33/96 ,  G01N2496/05 ,  Y10T436/101666

摘要： The invention is directed to novel stabilized blood compositions and methods of stabilizing blood compositions for use in the quality control of analytical techniques. The novel blood compositions comprise leucocytes and an effective amount of an aged transition metal solution. The novel method comprises removing leucocytes from a blood composition to yield a depleted blood composition, stabilizing the leucocytes by treatment with an effective amount of a stabilizing agent comprising an aged transition metal solution, and then, adding the resultant stabilized leucocytes to the depleted blood composition or a second blood component composition.

摘要翻译： 本发明涉及新颖的稳定血液组合物和稳定血液组合物的方法，用于分析技术的质量控制。 新型血液组合物包含白细胞和有效量的老化过渡金属溶液。 该新方法包括从血液组合物中除去白细胞以产生耗尽的血液组合物，通过用有效量的包含老化过渡金属溶液的稳定剂进行处理来稳定白细胞，然后将所得稳定的白细胞加入贫血血液组合物 或第二血液成分组合物。