公开(公告)号：US20130143229A1

公开(公告)日：2013-06-06

申请号：US13638622

申请日：2011-03-31

申请人： Yasuyuki Hara ,  Tetsuya Ota ,  Michiko Kawamoto ,  Shinya Sato ,  Shigehisa Iwamoto ,  Tatsuro Shimaoka ,  Shigeo Sudo

发明人： Yasuyuki Hara ,  Tetsuya Ota ,  Michiko Kawamoto ,  Shinya Sato ,  Shigehisa Iwamoto ,  Tatsuro Shimaoka ,  Shigeo Sudo

IPC分类号： C07K14/20 ,  G01N33/68

CPC分类号： C07K14/20 ,  G01N33/545 ,  G01N33/571 ,  G01N33/6854 ,  G01N2333/20 ,  G01N2469/20

摘要： To provide a reagent for assaying anti-Treponema pallidum antibody which reagent contains a polypeptide antigen and which reagent provides high assay sensitivity and high specificity, and to provide an assay method employing the assay reagent.The reagent for assaying anti-Treponema pallidum antibody, for use in an assay of anti-Treponema pallidum antibody on the basis of antigen-antibody reaction is characterized in that the reagent contains, as an antigen, a recombinant polypeptide containing at least domain C and domain D of Treponema pallidum 47 kDa antigen but containing no domain A1 of the 47 kDa antigen.

摘要翻译： 提供用于测定抗梅毒螺旋体抗体的试剂，该试剂含有多肽抗原，该试剂提供高测定灵敏度和高特异性，并提供使用测定试剂的测定方法。 基于抗原 - 抗体反应用于测定抗梅毒螺旋体抗体的抗梅毒螺旋体抗体的试剂的特征在于，所述试剂含有至少含有结构域C和 梅毒螺旋体47kDa抗原的结构域D，但不包含47kDa抗原的结构域A1。

公开(公告)号：US08969520B2

公开(公告)日：2015-03-03

申请号：US13638622

申请日：2011-03-31

申请人： Yasuyuki Hara ,  Tetsuya Ota ,  Michiko Kawamoto ,  Shinya Sato ,  Shigehisa Iwamoto ,  Tatsuro Shimaoka ,  Shigeo Sudo

发明人： Yasuyuki Hara ,  Tetsuya Ota ,  Michiko Kawamoto ,  Shinya Sato ,  Shigehisa Iwamoto ,  Tatsuro Shimaoka ,  Shigeo Sudo

IPC分类号： C07K14/20 ,  G01N33/571 ,  G01N33/545 ,  A61K39/02 ,  G01N33/68

CPC分类号： C07K14/20 ,  G01N33/545 ,  G01N33/571 ,  G01N33/6854 ,  G01N2333/20 ,  G01N2469/20

摘要： To provide a reagent for assaying anti-Treponema pallidum antibody which reagent contains a polypeptide antigen and which reagent provides high assay sensitivity and high specificity, and to provide an assay method employing the assay reagent.The reagent for assaying anti-Treponema pallidum antibody, for use in an assay of anti-Treponema pallidum antibody on the basis of antigen-antibody reaction is characterized in that the reagent contains, as an antigen, a recombinant polypeptide containing at least domain C and domain D of Treponema pallidum 47 kDa antigen but containing no domain A1 of the 47 kDa antigen.

摘要翻译： 提供用于测定抗梅毒螺旋体抗体的试剂，该试剂含有多肽抗原，该试剂提供高测定灵敏度和高特异性，并提供使用测定试剂的测定方法。 基于抗原 - 抗体反应用于测定抗梅毒螺旋体抗体的抗梅毒螺旋体抗体的试剂的特征在于，所述试剂含有至少含有结构域C和 梅毒螺旋体47kDa抗原的结构域D，但不包含47kDa抗原的结构域A1。