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1.发明授权公开(公告)号：US07736314B2
公开(公告)日：2010-06-15
申请号：US11218292
申请日：2005-08-31
申请人： Kirk W. Beach , Yongmin Kim , Siddhartha Sikdar
发明人： Kirk W. Beach , Yongmin Kim , Siddhartha Sikdar
IPC分类号： A61B8/00
CPC分类号： A61B5/02007 , A61B5/7257 , A61B8/08 , G01S7/52026 , G01S7/52034 , G01S7/52036 , G01S7/52071 , G01S15/8981
摘要： A real-time signal processing technique for ultrasonic imaging of tissue vibrations for localizing the source of a bruit in a 2D image with respect to the anatomy and/or for obtaining simultaneous information about vibrations and the underlying blood flow. The bruit can be quantitatively assessed using an ensemble of ultrasound echoes. Signal processing enables estimation of wall displacement and the display of time-resolved vibration spectrum. Vibrations are detected and color-coded according to their amplitude and frequency and overlaid on the B-mode and/or color-flow image in real time. Proposed vibration imaging algorithms use data acquired during conventional ultrasonic color-flow imaging and the clutter signal, normally suppressed in color-flow imaging, to detect and characterize tissue vibrations. Three vibration imaging algorithms based on parametric modeling of vibrations and other criteria distinguish between clutter, blood flow, and vibrations. The techniques are usable to detect, locate, image, and quantitatively grade stenoses in blood vessels.
摘要翻译： 一种实时信号处理技术，用于组织振动的超声成像，用于相对于解剖结构定位2D图像中的血管源，和/或用于获得关于振动和潜在血流的同时信息。 可以使用超声回波的整体来定量评估。 信号处理使得能够估计壁位移和时间分辨振动谱的显示。 根据振幅和频率对振动进行检测和颜色编码，并实时覆盖在B模式和/或彩色流动图像上。 建议的振动成像算法使用在常规超声彩色流动成像期间获取的数据和通常在彩色流动成像中抑制的杂波信号来检测和表征组织振动。 基于振动参数建模和其他标准的三种振动成像算法区分了杂波，血流和振动。 该技术可用于检测，定位，成像和定量评估血管狭窄。
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2.发明申请公开(公告)号：US20070066895A1
公开(公告)日：2007-03-22
申请号：US10574133
申请日：2004-10-01
申请人： Siddhartha Sikdar , Yongmin Kim , Kirk Beach
发明人： Siddhartha Sikdar , Yongmin Kim , Kirk Beach
IPC分类号： A61B8/00
CPC分类号： A61B8/06 , A61B8/13 , A61B8/488 , G01S15/8981
摘要： An ultrasound based technique for detecting and imaging vibrations in tissue caused by eddies produced during bleeding through punctured arteries or from organs. A clutter signal, normally suppressed in conventional color flow imaging, is employed to detect and characterize local tissue vibrations, to detect internal bleeding in an image, or as an audible or palpable signal, or a readout. Using a tissue vibration image, the origin and extent of vibrations relative to the underlying anatomy and blood flow can be visualized in real time, enabling measurements of vibration amplitude, frequency, and spatial distribution. Bleeding rate can be determined from the frequency and amplitude of the vibrations. Signal processing algorithms usable to identify tissue vibrations from an ensemble of 2D ultrasound data include those based on phase decomposition, spectral estimation using eigendecomposition, and spectral estimation using autoregressive modeling for isolating vibrations from clutter, blood flow, and noise.
摘要翻译： 一种基于超声的技术，用于检测和成像由穿刺的动脉或器官出血期间产生的涡流引起的组织中的振动。 通常在常规彩色流动成像中抑制的杂波信号被用于检测和表征局部组织振动，以检测图像中的内部出血，或者作为可听或触觉的信号或读出。 使用组织振动图像，可以实时显示相对于底层解剖和血流的振动的起点和程度，可以测量振幅，频率和空间分布。 出血率可以根据振动的频率和振幅来确定。 用于识别来自2D超声数据的组合的组织振动的信号处理算法包括基于相位分解，使用特征分解的频谱估计和使用自回归建模的频谱估计来分离来自杂波，血流和噪声的振动的信号处理算法。
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3.发明申请Interference-free ultrasound imaging during HIFU therapy, using software tools 有权HIFU治疗期间无干扰超声成像，使用软件工具公开(公告)号：US20060264748A1
公开(公告)日：2006-11-23
申请号：US11229000
申请日：2005-09-16
申请人： Shahram Vaezy , Robert Held , Siddhartha Sikdar , Ravi Managuli , Vesna Zderic
发明人： Shahram Vaezy , Robert Held , Siddhartha Sikdar , Ravi Managuli , Vesna Zderic
IPC分类号： A61B8/00
CPC分类号： A61B8/14 , A61B8/12 , A61B8/4488 , A61B8/463 , A61B8/465 , A61B8/467 , A61B8/469 , A61B8/54 , G01S7/52074 , G01S7/52077 , G01S15/899 , G01S15/8995
摘要： Disclosed herein is a method for obtaining a composite interference-free ultrasound image when non-imaging ultrasound waves would otherwise interfere with ultrasound imaging. A conventional ultrasound imaging system is used to collect frames of ultrasound image data in the presence of non-imaging ultrasound waves, such as high-intensity focused ultrasound (HIFU). The frames are directed to a processor that analyzes the frames to identify portions of the frame that are interference-free. Interference-free portions of a plurality of different ultrasound image frames are combined to generate a single composite interference-free ultrasound image that is displayed to a user. In this approach, a frequency of the non-imaging ultrasound waves is offset relative to a frequency of the ultrasound imaging waves, such that the interference introduced by the non-imaging ultrasound waves appears in a different portion of the frames.
摘要翻译： 本文公开了一种当非成像超声波将干扰超声成像时获得无复合干扰超声图像的方法。 在非成像超声波（例如高强度聚焦超声（HIFU））的存在下，常规的超声成像系统用于收集超声图像数据的帧。 这些帧被引导到处理器，该处理器分析帧以识别不干扰的帧的部分。 组合多个不同的超声图像帧的无干扰部分以产生向用户显示的单个无复合干扰的超声图像。 在该方法中，非成像超声波的频率相对于超声波成像波的频率偏移，使得由非成像超声波引入的干扰出现在帧的不同部分中。
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公开(公告)号：US20180280164A1
公开(公告)日：2018-10-04
申请号：US15937613
申请日：2018-03-27
摘要： The artificial body part control system using ultrasonic imaging includes of an ultrasonic transducer coupled with an ultrasonic image analyzer which may be adapted to transmit a control signal to an artificial body part.
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5.发明申请公开(公告)号：US20100286522A1
公开(公告)日：2010-11-11
申请号：US12815310
申请日：2010-06-14
申请人： Kirk W. Beach , Yongmin Kim , Siddhartha Sikdar
发明人： Kirk W. Beach , Yongmin Kim , Siddhartha Sikdar
IPC分类号： A61B8/14
CPC分类号： A61B8/08 , A61B5/02007 , A61B5/7257 , A61B8/06 , A61B8/0816 , A61B8/13 , G01S7/52026 , G01S7/52034 , G01S7/52036 , G01S7/52071 , G01S15/8981
摘要： A real-time signal processing technique for ultrasonic imaging of tissue vibrations for localizing the source of a bruit in a 2D image with respect to the anatomy and/or for obtaining simultaneous information about vibrations and the underlying blood flow. The bruit can be quantitatively assessed using an ensemble of ultrasound echoes. Signal processing enables estimation of wall displacement and the display of time-resolved vibration spectrum. Vibrations are detected and color-coded according to their amplitude and frequency and overlaid on the B-mode and/or color-flow image in real time. Proposed vibration imaging algorithms use data acquired during conventional ultrasonic color-flow imaging and the clutter signal, normally suppressed in color-flow imaging, to detect and characterize tissue vibrations. Three vibration imaging algorithms based on parametric modeling of vibrations and other criteria distinguish between clutter, blood flow, and vibrations. The techniques are usable to detect, locate, image, and quantitatively grade stenoses in blood vessels.
摘要翻译： 一种实时信号处理技术，用于组织振动的超声成像，用于相对于解剖结构定位2D图像中的血管源，和/或用于获得关于振动和潜在血流的同时信息。 可以使用超声回波的整体来定量评估。 信号处理使得能够估计壁位移和时间分辨振动谱的显示。 根据振幅和频率对振动进行检测和颜色编码，并实时覆盖在B模式和/或彩色流动图像上。 建议的振动成像算法使用在常规超声彩色流动成像期间获取的数据和通常在彩色流动成像中抑制的杂波信号来检测和表征组织振动。 基于振动参数建模和其他标准的三种振动成像算法区分了杂波，血流和振动。 该技术可用于检测，定位，成像和定量评估血管狭窄。
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公开(公告)号：US09931230B2
公开(公告)日：2018-04-03
申请号：US13564084
申请日：2012-08-01
CPC分类号： A61F2/72 , A61B5/1107 , A61B8/085 , A61B8/4227 , A61B8/5223 , A61F2/583 , A61F2002/6809 , A61F2002/7615
摘要： The artificial body part control system using ultrasonic imaging includes of an ultrasonic transducer coupled with an ultrasonic image analyzer which may be adapted to transmit a control signal to an artificial body part.
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7.发明授权公开(公告)号：US09066679B2
公开(公告)日：2015-06-30
申请号：US12815310
申请日：2010-06-14
申请人： Kirk W. Beach , Yongmin Kim , Siddhartha Sikdar
发明人： Kirk W. Beach , Yongmin Kim , Siddhartha Sikdar
CPC分类号： A61B8/08 , A61B5/02007 , A61B5/7257 , A61B8/06 , A61B8/0816 , A61B8/13 , G01S7/52026 , G01S7/52034 , G01S7/52036 , G01S7/52071 , G01S15/8981
摘要： A real-time signal processing technique for ultrasonic imaging of tissue vibrations for localizing the source of a bruit in a 2D image with respect to the anatomy and/or for obtaining simultaneous information about vibrations and the underlying blood flow. The bruit can be quantitatively assessed using an ensemble of ultrasound echoes. Signal processing enables estimation of wall displacement and the display of time-resolved vibration spectrum. Vibrations are detected and color-coded according to their amplitude and frequency and overlaid on the B-mode and/or color-flow image in real time. Proposed vibration imaging algorithms use data acquired during conventional ultrasonic color-flow imaging and the clutter signal, normally suppressed in color-flow imaging, to detect and characterize tissue vibrations. Three vibration imaging algorithms based on parametric modeling of vibrations and other criteria distinguish between clutter, blood flow, and vibrations. The techniques are usable to detect, locate, image, and quantitatively grade stenoses in blood vessels.
摘要翻译： 一种用于组织振动超声成像的实时信号处理技术，用于相对于解剖结构定位二维图像中的血管源，和/或用于获得关于振动和潜在血流的同时信息。 可以使用超声回波的整体来定量评估。 信号处理使得能够估计壁位移和时间分辨振动谱的显示。 根据振幅和频率对振动进行检测和颜色编码，并实时覆盖在B模式和/或彩色流动图像上。 建议的振动成像算法使用在常规超声彩色流动成像期间获取的数据和通常在彩色流动成像中抑制的杂波信号来检测和表征组织振动。 基于振动参数建模和其他标准的三种振动成像算法区分了杂波，血流和振动。 该技术可用于检测，定位，成像和定量评估血管狭窄。
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公开(公告)号：US20130041477A1
公开(公告)日：2013-02-14
申请号：US13564084
申请日：2012-08-01
IPC分类号： A61F2/66
CPC分类号： A61F2/72 , A61B5/1107 , A61B8/085 , A61B8/4227 , A61B8/5223 , A61F2/583 , A61F2002/6809 , A61F2002/7615
摘要： The artificial body part control system using ultrasonic imaging includes of an ultrasonic transducer coupled with an ultrasonic image analyzer which may be adapted to transmit a control signal to an artificial body part.
摘要翻译： 使用超声波成像的人造体部分控制系统包括与超声波图像分析器耦合的超声波换能器，该超声波换能器适于将控制信号发送到人造体部分。
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9.发明授权公开(公告)号：US07803116B2
公开(公告)日：2010-09-28
申请号：US10574133
申请日：2004-10-01
申请人： Siddhartha Sikdar , Yongmin Kim , Kirk Beach
发明人： Siddhartha Sikdar , Yongmin Kim , Kirk Beach
IPC分类号： A61B8/14
CPC分类号： A61B8/06 , A61B8/13 , A61B8/488 , G01S15/8981
摘要： An ultrasound based technique for detecting and imaging vibrations in tissue caused by eddies produced during bleeding through punctured arteries or from organs. A clutter signal, normally suppressed in conventional color flow imaging, is employed to detect and characterize local tissue vibrations, to detect internal bleeding in an image, or as an audible or palpable signal, or a readout. Using a tissue vibration image, the origin and extent of vibrations relative to the underlying anatomy and blood flow can be visualized in real time, enabling measurements of vibration amplitude, frequency, and spatial distribution. Bleeding rate can be determined from the frequency and amplitude of the vibrations. Signal processing algorithms usable to identify tissue vibrations from an ensemble of 2D ultrasound data include those based on phase decomposition, spectral estimation using eigendecomposition, and spectral estimation using autoregressive modeling for isolating vibrations from clutter, blood flow, and noise.
摘要翻译： 一种基于超声的技术，用于检测和成像由穿刺的动脉或器官出血期间产生的涡流引起的组织中的振动。 通常在常规彩色流动成像中抑制的杂波信号被用于检测和表征局部组织振动，以检测图像中的内部出血，或者作为可听或触觉的信号或读出。 使用组织振动图像，可以实时显示相对于底层解剖和血流的振动的起点和程度，可以测量振幅，频率和空间分布。 出血率可以根据振动的频率和振幅来确定。 用于识别来自2D超声数据的组合的组织振动的信号处理算法包括基于相位分解，使用特征分解的频谱估计和使用自回归建模的频谱估计来分离来自杂波，血流和噪声的振动的信号处理算法。
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10.发明授权Interference-free ultrasound imaging during HIFU therapy, using software tools 有权HIFU治疗期间无干扰超声成像，使用软件工具公开(公告)号：US07670291B2
公开(公告)日：2010-03-02
申请号：US11229000
申请日：2005-09-16
申请人： Shahram Vaezy , Robert Held , Siddhartha Sikdar , Ravi Managuli , Vesna Zderic
发明人： Shahram Vaezy , Robert Held , Siddhartha Sikdar , Ravi Managuli , Vesna Zderic
IPC分类号： A61B8/00
CPC分类号： A61B8/14 , A61B8/12 , A61B8/4488 , A61B8/463 , A61B8/465 , A61B8/467 , A61B8/469 , A61B8/54 , G01S7/52074 , G01S7/52077 , G01S15/899 , G01S15/8995
摘要： Disclosed herein is a method for obtaining a composite interference-free ultrasound image when non-imaging ultrasound waves would otherwise interfere with ultrasound imaging. A conventional ultrasound imaging system is used to collect frames of ultrasound image data in the presence of non-imaging ultrasound waves, such as high-intensity focused ultrasound (HIFU). The frames are directed to a processor that analyzes the frames to identify portions of the frame that are interference-free. Interference-free portions of a plurality of different ultrasound image frames are combined to generate a single composite interference-free ultrasound image that is displayed to a user. In this approach, a frequency of the non-imaging ultrasound waves is offset relative to a frequency of the ultrasound imaging waves, such that the interference introduced by the non-imaging ultrasound waves appears in a different portion of the frames.
摘要翻译： 本文公开了一种当非成像超声波将干扰超声成像时获得无复合干扰超声图像的方法。 在非成像超声波（例如高强度聚焦超声（HIFU））的存在下，常规的超声成像系统用于收集超声图像数据的帧。 这些帧被引导到处理器，该处理器分析帧以识别不干扰的帧的部分。 组合多个不同的超声图像帧的无干扰部分以产生向用户显示的单个无复合干扰的超声图像。 在该方法中，非成像超声波的频率相对于超声波成像波的频率偏移，使得由非成像超声波引入的干扰出现在帧的不同部分中。
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