公开(公告)号：US20140296477A1

公开(公告)日：2014-10-02

申请号：US14131275

申请日：2012-07-06

申请人： Stéphane Dedieu ,  Nicolas Floquet ,  Laurent Martiny ,  Christophe Schneider ,  Albin Jeanne ,  Emilie Sick ,  Manuel Dauchez

发明人： Stéphane Dedieu ,  Nicolas Floquet ,  Laurent Martiny ,  Christophe Schneider ,  Albin Jeanne ,  Emilie Sick ,  Manuel Dauchez

IPC分类号： C07K7/08 ,  C07K7/64 ,  C07K7/06

CPC分类号： C07K7/08 ,  A61K38/00 ,  C07K7/06 ,  C07K7/64 ,  C07K14/78

摘要： Antagonist peptide of the bond between CD47 and a protein belonging to the thrombospondin family has the sequence S1 R1-R2-R3-S-Q-L-L-K-G-R4-R5-R6 and interacts specifically with the C-terminal end of the TSP, at the site of the bond between the TSP and the CD47 receptor. Interaction between the CD47 receptor and the protein is prevented. The peptide can be used in the context of cancer treatments.

摘要翻译： CD47与属于血小板反应蛋白家族的蛋白质之间的键的拮抗肽具有序列S1 R1-R2-R3-SQLLKG-R4-R5-R6，并与TSP的C末端特异性相互作用 TSP与CD47受体之间的结合。 防止CD47受体与蛋白质之间的相互作用。 该肽可用于癌症治疗的上下文中。

公开(公告)号：US20110081035A1

公开(公告)日：2011-04-07

申请号：US12923695

申请日：2010-10-05

申请人： Stéphane Dedieu ,  Ian McIntosh

发明人： Stéphane Dedieu ,  Ian McIntosh

IPC分类号： H04R1/20

CPC分类号： H04R1/2819 ,  H04R1/1016 ,  H04R1/2826 ,  H04R1/2842

摘要： An in-ear device comprises inter alia a miniaturized receiver assembly of sandwich construction with a front plate and a back plate and an electro-dynamic receiver therebetween, the assembly providing a bass-reflex design with a front resonator.

摘要翻译： 入耳式装置尤其包括具有前板和后板的夹层结构的小型化接收器组件和其间的电动接收器，该组件提供具有前谐振器的低音反射设计。

公开(公告)号：US09605025B2

公开(公告)日：2017-03-28

申请号：US14131275

申请日：2012-07-06

申请人： Stéphane Dedieu ,  Nicolas Floquet ,  Laurent Martiny ,  Christophe Schneider ,  Albin Jeanne ,  Emilie Sick ,  Manuel Dauchez

发明人： Stéphane Dedieu ,  Nicolas Floquet ,  Laurent Martiny ,  Christophe Schneider ,  Albin Jeanne ,  Emilie Sick ,  Manuel Dauchez

IPC分类号： C07K7/08 ,  C07K7/06 ,  C07K7/64 ,  C07K14/78 ,  A61K38/00

CPC分类号： C07K7/08 ,  A61K38/00 ,  C07K7/06 ,  C07K7/64 ,  C07K14/78

摘要： Antagonist peptide of the bond between CD47 and a protein belonging to the thrombospondin family has the sequence S1 R1-R2-R3-S-Q-L-L-K-G-R4-R5-R6 and interacts specifically with the C-terminal end of the TSP, at the site of the bond between the TSP and the CD47 receptor. Interaction between the CD47 receptor and the protein is prevented. The peptide can be used in the context of cancer treatments.

公开(公告)号：US20210153461A1

公开(公告)日：2021-05-27

申请号：US16480915

申请日：2018-01-26

申请人： Daniel FERLAND ,  Stéphane DEDIEU

发明人： Daniel FERLAND ,  Stéphane DEDIEU

IPC分类号： A01K15/02 ,  A01K11/00 ,  A01K29/00 ,  H04R1/10

摘要： An interactive animal earphone device for providing noise attenuation, as well as voice commands, in noisy environments is described. The device typically includes a core member, and an audio processing system (at least a processing device combined with an in-ear speaker, and alternatively, combined with an outer-ear microphone and an in-ear canal microphone) for capturing/transmitting/interpreting sounds from the animal (including biological noises captured in the ear canal) and digitally controlling over the animal perception of its sound environment. The earphone device may further include, without limitation, a tracking technology (GPS module), a gyroscope, health monitoring sensors, a wireless module, and a memory for storing data recorded from in-ear canal and outer-ear microphones and other sensors. Along with voice commands and sounds from the animal, data from all sensors, the gyroscope, and the GPS module can be sent to a receiving device or external device, such as, without limitation, a smartphone, a computer and/or a tablet, in real-time over a wireless network, either cellular network, WLAN or wireless personal area network (WPAN) (Bluetooth™).

公开(公告)号：US08422719B2

公开(公告)日：2013-04-16

申请号：US12923695

申请日：2010-10-05

申请人： Stéphane Dedieu ,  Ian McIntosh

发明人： Stéphane Dedieu ,  Ian McIntosh

IPC分类号： H04R25/00

CPC分类号： H04R1/2819 ,  H04R1/1016 ,  H04R1/2826 ,  H04R1/2842

摘要： An in-ear device comprises inter alia a miniaturized receiver assembly of a sealed sandwich construction with a front plate and a back plate and an electro-dynamic receiver therebetween, the assembly providing a bass-reflex design with a front resonator.

摘要翻译： 入耳式装置尤其包括具有前板和后板的密封夹层结构的小型化接收器组件和其间的电动接收器，该组件提供具有前谐振器的低音反射设计。