利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

14 条记录 (耗时 0.013 秒)

    Stable, non-aqueous, single-phase gels and formulations thereof for delivery from an implantable device
    1.
    发明申请
    Stable, non-aqueous, single-phase gels and formulations thereof for delivery from an implantable device 审中-公开
    稳定的非水性单相凝胶及其制剂用于从可植入装置输送

    公开(公告)号：US20090087408A1

    公开(公告)日：2009-04-02

    申请号：US12315194

    申请日：2008-11-26

    申请人： Stephen Berry ,  Pamela Fereira ,  Gunjan Junnarkar ,  Michael Desjardin

    发明人： Stephen Berry ,  Pamela Fereira ,  Gunjan Junnarkar ,  Michael Desjardin

    IPC分类号： A61K38/00 ,  A61K38/21

    CPC分类号： A61K9/0004 ,  A61K9/0024 ,  A61K47/26 ,  A61L24/001

    摘要： The present invention provides a suspension vehicle and suspension formulations deliverable from an implantable delivery device. In particular, the suspension vehicle of the present invention allows the formulation of beneficial agent suspensions that are stable over time at ambient and physiological temperatures. In addition, the beneficial agent suspensions formed using the suspension vehicle of the present invention allow controlled delivery of beneficial agent from an implanted delivery device over sustained periods of time, even when such delivery occurs at low flow rates, through a small-diameter delivery channel. Also included in the present invention are implantable delivery devices.

    摘要翻译： 本发明提供了可从可植入递送装置递送的悬浮液和悬浮液制剂。 特别地，本发明的悬浮载体允许制备在环境和生理温度下随时间稳定的有益试剂悬浮液。 此外，使用本发明的悬浮载体形成的有益剂悬浮液允许从持久的时间段内从植入的输送装置控制递送有益剂，即使当这种递送以低流速通过小直径输送通道 。 本发明还包括可植入递送装置。

    Osmotic delivery system and method for decreasing start-up times for osmotic delivery systems
    2.
    发明申请
    Osmotic delivery system and method for decreasing start-up times for osmotic delivery systems 审中-公开
    渗透输送系统和减少渗透输送系统启动时间的方法

    公开(公告)号：US20050010196A1

    公开(公告)日：2005-01-13

    申请号：US10815169

    申请日：2004-03-31

    申请人： Pamela Fereira ,  Scott Lautenbach ,  Stephen Berry

    发明人： Pamela Fereira ,  Scott Lautenbach ,  Stephen Berry

    IPC分类号： A61K9/00 ,  A61K9/20 ,  A61K9/22 ,  A61K31/00 ,  A61K47/10

    CPC分类号： A61K9/2013 ,  A61K9/0004 ,  A61K9/2027 ,  A61K9/205 ,  A61K9/2054 ,  A61K31/00 ,  A61K47/10

    摘要： The present invention includes devices and methods for reducing the start-up time of osmotically driven drug delivery systems capable of delivering a desired drug at a controlled rate over time. In particular, the present invention includes osmotic pumps that have a preloaded membrane, which includes a semipermeable material that has been preloaded with a nonaqueous, incompressible liquid filler that is miscible with water. The present invention further includes methods for making such osmotic pumps. The preloaded membranes included in the osmotic pumps according to the present invention have proven to provide significant decreases in average start-up times relative to osmotic pumps that include semipermeable membranes that are not preloaded.

    摘要翻译： 本发明包括用于减少能够以受控速率随时间输送所需药物的渗透驱动的药物递送系统的启动时间的装置和方法。 特别地，本发明包括具有预加载膜的渗透泵，其包括预先装有与水混溶的非水不可压缩液体填料的半透性材料。 本发明还包括制造这种渗透泵的方法。 包括在根据本发明的渗透泵中的预加载膜已被证明相对于包括未预加载的半透膜的渗透泵的平均启动时间显着减少。

    Non-aqueous single phase vehicles and formulations utilizing such vehicles
    3.
    发明申请
    Non-aqueous single phase vehicles and formulations utilizing such vehicles 审中-公开
    非水单相车辆和使用这种车辆的配方

    公开(公告)号：US20050008661A1

    公开(公告)日：2005-01-13

    申请号：US10814826

    申请日：2004-03-31

    申请人： Pamela Fereira ,  Michael Desjardin ,  Catherine Rohloff ,  Stephen Berry

    发明人： Pamela Fereira ,  Michael Desjardin ,  Catherine Rohloff ,  Stephen Berry

    IPC分类号： A61K9/00 ,  A61K9/14 ,  A61K38/00 ,  A61K38/09 ,  A61K38/18 ,  A61K38/22 ,  A61K48/00

    CPC分类号： A61K47/32 ,  A61K9/0004

    摘要： The present invention includes materials and methods for providing vehicles useful for providing drug formulations that address the potential drawbacks of known nonaqueous formulations. In particular, the present invention includes nonaqueous vehicles that are formed using a combination of polymer and solvent that results in a vehicle that is miscible in water. The nonaqueous vehicles facilitate the formulation of drug formulations that are stable over time, even when stored at, or exposed to, elevated temperatures. Moreover, the miscible vehicles of the present invention allow the preparation of drug formulations that work to reduce the occurrence of partial or complete occlusions of the delivery conduits included in delivery devices used to administer the drug formulations.

    摘要翻译： 本发明包括用于提供可用于提供药物制剂的载体的材料和方法，其解决已知非水性制剂的潜在缺点。 特别地，本发明包括使用聚合物和溶剂的组合形成的非水载体，其导致在水中可混溶的载体。 非水性载体促进药物制剂的配制，其随着时间的推移是稳定的，即使在高温下储存或暴露于其中时也是如此。 此外，本发明的可混溶的载体允许制备药物制剂，其用于减少包括在用于施用药物制剂的递送装置中的输送管道的部分或完全闭塞的发生。

    Power converter control loop
    4.
    发明授权
    Power converter control loop 失效
    电源转换器控制回路

    公开(公告)号：US06421257B2

    公开(公告)日：2002-07-16

    申请号：US09780607

    申请日：2001-02-12

    申请人： Stephen John MacKay ,  Stephen Berry

    发明人： Stephen John MacKay ,  Stephen Berry

    IPC分类号： H02M112

    CPC分类号： H02M3/156

    摘要： An apparatus for and method of control of a switch (102) in an electrical power converter (100) using pulse width modulation to regulate output voltage (112) and current The method allows precise output voltage regulation to be achieved whilst accurately controlling the proportion of load-current supplied by multiple modules connected in parallel. A ramped waveform (408), consisting of a component representing the instantaneous current and a component representing the input voltage applied since the switch (102) switched on in the current PWM cycle, is compared with an error signal (406) to determine the width of each PWM pulse.

    摘要翻译： 一种使用脉冲宽度调制来调节输出电压（112）和电流的电力转换器（100）中的开关（102）的控制装置和方法。该方法允许精确的输出电压调节，同时精确地控制 由并联连接的多个模块提供的负载电流。 将表示瞬时电流的分量和表示在当前PWM周期中接通的开关（102）所施加的输入电压的分量的斜坡波形（408）与误差信号（406）进行比较，以确定宽度 的每个PWM脉冲。

    Article of apparel incorporating a separable electronic device
    7.
    发明申请
    Article of apparel incorporating a separable electronic device 有权
    包含可分离电子设备的服装文章

    公开(公告)号：US20060117458A1

    公开(公告)日：2006-06-08

    申请号：US10987577

    申请日：2004-11-12

    申请人： James Ishihara ,  Scott Wilson ,  Stephen Berry

    发明人： James Ishihara ,  Scott Wilson ,  Stephen Berry

    IPC分类号： A41D20/00

    CPC分类号： A44C5/14 ,  A41D1/002 ,  G04B37/1486 ,  G04G17/00 ,  G04G17/08 ,  G06F1/163

    摘要： An article of apparel is disclosed that includes an electronic device. The apparel is at least partially formed from a material element that defines an aperture. The electronic device is locatable within the aperture and removably-securable to the material element. The electronic device may be a timing device, such as a watch, or a global positioning system unit. The apparel may be a wristband formed from a textile material or any of a variety of other types of apparel.

    摘要翻译： 公开了一种包括电子设备的服饰品。 服饰至少部分地由限定孔的材料元件形成。 电子设备可定位在孔内并可拆卸地固定到材料元件上。 电子设备可以是定时设备，例如手表或全球定位系统单元。 服装可以是由纺织材料或各种其他类型的服装中的任何一种形成的腕带。

    Method and apparatus for high density sixteen and thirty-two megabyte single in-line memory module
    8.
    发明授权
    Method and apparatus for high density sixteen and thirty-two megabyte single in-line memory module 失效
    用于高密度16和32兆字节单列直插式存储器模块的方法和装置

    公开(公告)号：US5504700A

    公开(公告)日：1996-04-02

    申请号：US199714

    申请日：1994-02-22

    申请人： Mark Insley ,  Stephen Berry ,  Jay C. Robinson

    发明人： Mark Insley ,  Stephen Berry ,  Jay C. Robinson

    IPC分类号： G11C5/00 ,  G11C5/04

    CPC分类号： G11C5/04 ,  H01L25/18 ,  H01L2924/0002

    摘要： The invention provides a method and apparatus for a memory device interface between a memory device and a CPU as well as the dimensions of the memory device. An electric circuit of the present invention has one-hundred-twenty pins along the length of the housing. The housing of the memory device has a length of approximately 85.6 mm and a width of approximately 54.0 mm. The left and right side socket interface portions of the housing have a minimum width of approximately 3.3 mm. The top socket interface portion has a maximum thickness of approximately 3.5 mm and a minimum height of approximately 3.0 mm. The bottom socket interface portion has a maximum thickness of approximately 5.0 mm and a minimum height of approximately 10.5 mm. Furthermore, the memory device interface portion of the present invention includes at least one pin which provides access to an address signal which indicates a memory array address location within the memory device. The interface portion also includes at least one pin which provides access to a data signal. Additionally, the interface portion includes a row address strobe signal which indicates that the address signal provided to the memory device is a row address, similarly at least one pin providing access to a column address strobe signal is included in the interface portion of the present invention. This column address strobe signal indicates that the address signal provided to the memory device is a column address. Further, at least one pin providing access to a memory write signal and at least one pin providing access to a memory output enable signal are included in the interface portion. Finally, the memory device interface of the present invention provides access to a power supply and to ground.

    摘要翻译： 本发明提供了一种用于存储器件与CPU之间的存储器件接口以及存储器件的尺寸的方法和装置。 本发明的电路沿着壳体的长度具有一百二十个销。 存储装置的外壳的长度约为85.6毫米，宽度约为54.0毫米。 壳体的左侧和右侧插座接口部分具有大约3.3mm的最小宽度。 顶部插座接口部分具有约3.5mm的最大厚度和约3.0mm的最小高度。 底部插座接口部分具有大约5.0mm的最大厚度和大约10.5mm的最小高度。 此外，本发明的存储器件接口部分包括至少一个引脚，其提供对指示存储器件内的存储器阵列地址位置的地址信号的访问。 接口部分还包括提供对数据信号的访问的至少一个引脚。 此外，接口部分包括指示提供给存储器件的地址信号是行地址的行地址选通信号，类似地，提供对列地址选通信号的访问的至少一个引脚包括在本发明的接口部分中 。 该列地址选通信号指示提供给存储器件的地址信号是列地址。 此外，在接口部分中包括提供对存储器写入信号的访问的至少一个引脚和提供对存储器输出使能信号的访问的至少一个引脚。 最后，本发明的存储器件接口提供对电源和接地的访问。