Iontophoretic drug delivery system, including method for activating same
for attachment to patient
    6.
    发明授权
    Iontophoretic drug delivery system, including method for activating same for attachment to patient 失效
    离子电渗药物递送系统,包括用于激活其以用于附着于患者的方法

    公开(公告)号:US5797867A

    公开(公告)日:1998-08-25

    申请号:US722816

    申请日:1996-09-27

    IPC分类号: A61N1/30

    CPC分类号: A61N1/0448 A61N1/303

    摘要: The user activated iontophoretic device of the present invention includes a disposable patch and a reusable controller. The patch contains an electrode assembly, an electrode reservoir and at least one drug reservoir. The patch is divided or otherwise separated into at least two portions, with one portion containing the electrode reservoir and the other containing the drug reservoir, which may include a medication in a dry form. The electrode reservoir and the drug reservoir are sealingly separated by a barrier, which can be manipulated to bring the reservoirs into fluid conducting contact with one another. A method of activating the device includes causing the two portions to rotate about a central axis relative to one another to manipulate the barrier and bring the reservoirs into fluid conducting contact with one another to at least partially hydrate one of the reservoirs. In this way, the device is suitable for use to deliver a drug which has limited stability in an aqueous solution.

    摘要翻译: 用户激活的本发明的离子电渗疗法装置包括一次性贴片和可重复使用的控制器。 补片包含电极组件,电极储存器和至少一个药物储存器。 贴片被分割或以其他方式分成至少两部分,其中一部分含有电极储存器,另一部分包含药物储存器,其可以包括干燥形式的药物。 电极储存器和药物贮存器通过屏障密封地分开,该屏障可以被操纵以使储存器彼此流体地导电接触。 激活装置的方法包括使两个部分相对于彼此围绕中心轴线旋转以操纵阻挡件并使储存器彼此流体导电接触以至少部分地水合其中一个储存器。 以这种方式,该装置适用于递送在水溶液中具有有限稳定性的药物。