公开(公告)号：US20050042772A1

公开(公告)日：2005-02-24

申请号：US10773442

申请日：2004-02-06

Applicant: Stephen Naylor ,  Jiri Ademec ,  Michael Meys

Inventor： Stephen Naylor ,  Jiri Ademec ,  Michael Meys

IPC: B01D15/18 ,  B01D15/38 ,  C07K1/36 ,  G01N30/08 ,  G01N30/14 ,  G01N30/46 ,  G01N33/543

CPC classification number: G01N30/461 ,  B01D15/1871 ,  B01D15/3804 ,  C07K1/36 ,  G01N30/14 ,  G01N2030/085 ,  G01N2030/143

Abstract: In various aspects, provided are methods and devices for the depletion of two or more proteins from a sample, such as, for example, blood serum, blood plasma, cerebrospinal fluid and/or urine samples. In various embodiments, the methods deplete three or more proteins from a sample by contacting the sample with at least one chromatographic medium, the at least one chromatographic medium being capable of removing albumin, IgG, and a third abundant protein from the sample. In various embodiments, the devices comprise a first chromatography column functionalized to substantially remove a first abundant protein from the sample; a second chromatography column in serial fluidic communication with the first chromatography column and functionalized to substantially remove a second abundant protein from the sample; and a first chromatography disk in serial fluidic communication with the second chromatography column and functionalized to substantially remove a third protein from the sample.

Abstract translation: 在各个方面，提供了用于从样品（例如血清，血浆，脑脊髓液和/或尿液样品）中消耗两种或更多种蛋白质的方法和装置。 在各种实施方案中，所述方法通过使样品与至少一种色谱介质接触而从样品中消耗三种或更多种蛋白质，该至少一种色谱介质能够从样品中除去白蛋白，IgG和第三种丰富的蛋白质。 在各种实施方案中，所述装置包括功能化以从样品中基本上除去第一丰富蛋白质的第一层析柱; 第二色谱柱与第一色谱柱连续流体连通，并被功能化以从样品中基本上除去第二种丰富的蛋白质; 和与第二层析柱连续流体连通并被功能化以从样品中基本上除去第三种蛋白质的第一层析盘。

公开(公告)号：US20080014368A1

公开(公告)日：2008-01-17

申请号：US11789834

申请日：2007-04-25

Applicant: Wolfgang Feyrer ,  Andrew Duda ,  Stephen Naylor ,  Harald Kloeckner

Inventor： Wolfgang Feyrer ,  Andrew Duda ,  Stephen Naylor ,  Harald Kloeckner

IPC: C08J7/18

CPC classification number: B05D3/0263 ,  B05D7/14 ,  B05D7/532

Abstract: The invention is directed to a method for refinishing vehicles using infrared technology for drying and curing the paint coating. The method comprises the steps: A) applying a layer of a pigmented coating composition over a vehicle body or vehicle body part, subsequently applying a layer of clear coating composition, or applying alternatively a layer of pigmented top coating composition over the vehicle body or vehicle body part and B) curing the coating layers applied in step A), directly after completion of the application step, without interposing a final evaporation phase, by exposing to infrared radiation using a short-wave infrared radiator, a radiator distance in the range of 20 to 60 cm being adjusted and the quotient of radiator power in Kilowatt and radiator distance in centimeter ranges from 0.07 to 0.15.

Abstract translation: 本发明涉及一种使用红外线技术来修补车辆来干燥和固化涂料的方法。 该方法包括以下步骤：A）在车体或车体部分上施加着色的涂料组合物层，随后施加一层透明涂料组合物，或者另外施加一层着色的顶涂层组合物在车身或车辆上 主体部分和B）在步骤A）中直接施加的涂层，在施加步骤完成之后，通过使用短波红外辐射器暴露于红外辐射而不插入最终蒸发相，在 调节20至60厘米，散热器功率（千瓦）和散热器距离（厘米）范围为0.07至0.15。

公开(公告)号：US20110136241A1

公开(公告)日：2011-06-09

申请号：US12633205

申请日：2009-12-08

Applicant: Stephen Naylor

Inventor： Stephen Naylor

IPC: G01N33/72 ,  G01N33/48 ,  G01N33/68 ,  G01N33/92 ,  G01N33/20

CPC classification number: G01N33/6893 ,  G01N2800/042 ,  G01N2800/60 ,  Y10T436/144444 ,  Y10T436/147777 ,  Y10T436/201666

Abstract: Molecular bioprofiles comprising biologically correlated and relevant analytes that impact the biological state of a human health condition compared to a control population are provided. These molecular bioprofiles are useful in several ways including but not limited to, monitoring a disease or condition's progression, evaluating the impact of an agent or compound on a disease or condition, evaluating the impact of a lifestyle change on a disease or condition and assessing the risk of the disease or condition to a subject. Type II diabetes molecular bioprofiles are of particular interest.

Abstract translation: 提供了包含与对照群体相比影响人类健康状况的生物学状态的生物相关和相关分析物的分子生物学方案。 这些分子生物制剂在多种方式中是有用的，包括但不限于监测疾病或病症的进展，评估药物或化合物对疾病或病症的影响，评估生活方式改变对疾病或病症的影响并评估 疾病或状况对受试者的风险。 II型糖尿病分子生物制剂特别引人关注。

公开(公告)号：US20100076787A1

公开(公告)日：2010-03-25

申请号：US12558037

申请日：2009-09-11

Applicant: Stephen Naylor ,  Brian Kleber ,  Christa Curtis ,  Autumn Workman ,  Scott Beason

Inventor： Stephen Naylor ,  Brian Kleber ,  Christa Curtis ,  Autumn Workman ,  Scott Beason

IPC: G06Q50/00 ,  A61B5/00 ,  G06Q10/00 ,  G06T11/20

CPC classification number: G06Q50/24 ,  G06Q50/22 ,  G16H15/00

Abstract: A method for preparing a medical report. Some example methods include receiving one or more medical data readings, where respective individual medical data readings include a numerical result of a medical test; processing the medical data readings into report data, where the report data includes the individual medical data readings and categorized ranges associated with the medical tests associated with individual medical data readings; and creating a medical data report including the report data, graphical representations of individual medical data readings and the respective categorized ranges, and textual descriptive information pertaining to the respective medical data readings.

Abstract translation: 制定医疗报告的方法。 一些示例性方法包括接收一个或多个医疗数据读数，其中相应的个体医学数据读数包括医学测试的数值结果; 将医疗数据读取处理为报告数据，其中报告数据包括与各个医疗数据读数相关联的医学测试相关联的各个医疗数据读数和分类范围; 以及创建包括报告数据，各个医疗数据读数的图形表示和相应的分类范围的医疗数据报告以及与各个医疗数据读数相关的文本描述信息。

公开(公告)号：US5800692A

公开(公告)日：1998-09-01

申请号：US423220

申请日：1995-04-17

Applicant: Stephen Naylor ,  Andrew J. Tomlinson ,  Linda M. Benson ,  Walter David Braddock ,  Robert P. Oda

Inventor： Stephen Naylor ,  Andrew J. Tomlinson ,  Linda M. Benson ,  Walter David Braddock ,  Robert P. Oda

IPC: G01N27/447 ,  G01N27/26

CPC classification number: G01N27/44743

Abstract: A preseparation processor for use in capillary electrophoresis is described. The preseparation processor contains sample processing material, preferably in the form of a membrane, for use in concentrating or chemically processing a sample, or catalyzing a chemical reaction. It is particularly suited to the concentration of dilute samples or the purification of contaminated samples. The preseparation processor facilitates reliable and reproducible separation of analytes by eliminating inconsistencies caused by a reversal of the electroosmotic flow otherwise induced by the sample processing material.

Abstract translation: 描述了用于毛细管电泳的预分离处理器。 预分离处理器包含样品处理材料，优选以膜的形式，用于浓缩或化学处理样品或催化化学反应。 它特别适用于稀释样品的浓缩或污染样品的纯化。 预分离处理器通过消除由样品处理材料导致的电渗流反转引起的不一致性，便于分析物的可靠和可再现的分离。