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公开(公告)号：US08367673B2
公开(公告)日：2013-02-05
申请号：US12412837
申请日：2009-03-27
申请人： Alan David Borthwick , Richard Jonathan Hatley , Deirdre Mary Bernadette Hickey , John Liddle , David George Hubert Livermore , Andrew McMurtrie Mason , Neil Derek Miller , Fabrizio Nerozzi , Steven Leslie Sollis , Anna Katrin Szardenings , Paul Graham Wyatt
发明人： Alan David Borthwick , Richard Jonathan Hatley , Deirdre Mary Bernadette Hickey , John Liddle , David George Hubert Livermore , Andrew McMurtrie Mason , Neil Derek Miller , Fabrizio Nerozzi , Steven Leslie Sollis , Anna Katrin Szardenings , Paul Graham Wyatt
IPC分类号： A61K31/497 , A61K31/4965
CPC分类号： C07D241/08 , A61K38/00 , C07D401/10 , C07D403/06 , C07D413/10 , C07D417/06 , C07K5/06078 , C07K5/06191
摘要： A method of treating or preventing diseases or conditions mediated through the action of oxytocin which comprises administering to a human in need thereof of an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof.
摘要翻译： 一种治疗或预防通过催产素作用介导的疾病或病症的方法，其包括向有需要的人施用有效量的式（I）化合物或其药学上可接受的盐。
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公开(公告)号：US20120053150A1
公开(公告)日：2012-03-01
申请号：US13265037
申请日：2010-04-22
申请人： David George Allen , Diane Mary Coe , Anthony William James Cooper , Paul Martin Gore , David House , Stefan Senger , Steven Leslie Sollis , Sadie Vile , Caroline Wilson
发明人： David George Allen , Diane Mary Coe , Anthony William James Cooper , Paul Martin Gore , David House , Stefan Senger , Steven Leslie Sollis , Sadie Vile , Caroline Wilson
IPC分类号： A61K31/675 , C07D401/12 , C07D403/10 , C07D413/10 , C07D413/12 , C07D403/12 , C07F9/6503 , A61K31/415 , A61K31/4439 , A61K31/4245 , A61K31/422 , A61K31/513 , A61P11/06 , A61P29/00 , C07D231/40
CPC分类号： C07D231/40
摘要： The present invention relates to amide compounds, processes for their preparation, pharmaceutical compositions containing these compounds and to their use in the treatment of disorders, conditions or disorders such as allergic disorders, inflammatory disorders and disorders of the immune system.
摘要翻译： 本发明涉及酰胺化合物，其制备方法，含有这些化合物的药物组合物及其用于治疗疾病，病症或病症如过敏性疾病，炎症性疾病和免疫系统疾病的用途。
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公开(公告)号：US08399436B2
公开(公告)日：2013-03-19
申请号：US13265037
申请日：2010-04-22
申请人： David George Allen , Diane Mary Coe , Anthony William James Cooper , Paul Martin Gore , David House , Stefan Senger , Steven Leslie Sollis , Sadie Vile , Caroline Wilson
发明人： David George Allen , Diane Mary Coe , Anthony William James Cooper , Paul Martin Gore , David House , Stefan Senger , Steven Leslie Sollis , Sadie Vile , Caroline Wilson
IPC分类号： A61K31/675 , A61K31/415 , A61K31/4439 , A61K31/4245 , A61K31/513 , A61P11/06 , C07D401/12 , C07D403/10 , C07D413/12
CPC分类号： C07D231/40
摘要： The present invention relates to amide compounds, processes for their preparation, pharmaceutical compositions containing these compounds and to their use in the treatment of disorders, conditions or disorders such as allergic disorders, inflammatory disorders and disorders of the immune system.
摘要翻译： 本发明涉及酰胺化合物，其制备方法，含有这些化合物的药物组合物及其用于治疗疾病，病症或病症如过敏性疾病，炎症性疾病和免疫系统疾病的用途。
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公开(公告)号：US20100273744A1
公开(公告)日：2010-10-28
申请号：US12765021
申请日：2010-04-22
IPC分类号： A61K31/675 , C07F9/06 , C07D231/38 , A61K31/415 , A61P11/06 , A61P11/00
CPC分类号： C07D231/40
摘要： The present invention relates to amide compounds, processes for their preparation, pharmaceutical compositions containing these compounds and to their use in the treatment of disorders, conditions or disorders such as allergic disorders, inflammatory disorders and disorders of the immune system.
摘要翻译： 本发明涉及酰胺化合物，其制备方法，含有这些化合物的药物组合物及其用于治疗疾病，病症或病症如过敏性疾病，炎症性疾病和免疫系统疾病的用途。
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公开(公告)号：US07514437B2
公开(公告)日：2009-04-07
申请号：US10499177
申请日：2002-12-20
申请人： Alan David Borthwick , Richard Jonathan Hatley , Deirdre Mary Bernadette Hickey , John Liddle , David George Hubert Livermore , Andrew McMurtrie Mason , Neil Derek Miller , Fabrizio Nerozzi , Steven Leslie Sollis , Anna Katrin Szardenings , Paul Graham Wyatt
发明人： Alan David Borthwick , Richard Jonathan Hatley , Deirdre Mary Bernadette Hickey , John Liddle , David George Hubert Livermore , Andrew McMurtrie Mason , Neil Derek Miller , Fabrizio Nerozzi , Steven Leslie Sollis , Anna Katrin Szardenings , Paul Graham Wyatt
IPC分类号： A61K31/497 , A61K31/4965 , C07D241/00 , C07D241/02
CPC分类号： C07D241/08 , A61K38/00 , C07D401/10 , C07D403/06 , C07D413/10 , C07D417/06 , C07K5/06078 , C07K5/06191
摘要： A method of treating or preventing diseases or conditions mediated through the action of oxytocin which comprises administering to a mammal in need thereof of an effective amount of a compound of the formula (I) and/or a physiologically acceptable derivative thereof, wherein the substituents have the meaning given in the description. Disclosed are also novel compounds of formula (I) and processes for their preparation.
摘要翻译： 一种治疗或预防通过催产素作用介导的疾病或病症的方法，其包括向有需要的哺乳动物施用有效量的式（I）化合物和/或其生理上可接受的衍生物，其中所述取代基具有 说明中给出的含义。 公开了式（I）的新化合物及其制备方法。
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公开(公告)号：US20090186867A1
公开(公告)日：2009-07-23
申请号：US12412837
申请日：2009-03-27
申请人： Alan David Borthwick , Richard Jonathan Hatley , Deirdre Mary Bernadette Hickey , John Liddle , David George Hubert Livermore , Andrew McMurtrie Mason , Neil Derek Miller , Fabrizio Nerozzi , Steven Leslie Sollis , Anna Katrin Szardenings , Paul Graham Wyatt
发明人： Alan David Borthwick , Richard Jonathan Hatley , Deirdre Mary Bernadette Hickey , John Liddle , David George Hubert Livermore , Andrew McMurtrie Mason , Neil Derek Miller , Fabrizio Nerozzi , Steven Leslie Sollis , Anna Katrin Szardenings , Paul Graham Wyatt
IPC分类号： A61K31/496 , A61K31/4965 , A61K31/5377 , A61K31/541 , A61K31/551 , A61P15/00
CPC分类号： C07D241/08 , A61K38/00 , C07D401/10 , C07D403/06 , C07D413/10 , C07D417/06 , C07K5/06078 , C07K5/06191
摘要： A method of treating or preventing diseases or conditions mediated through the action of oxytocin which comprises administering to a human in need thereof of an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof.
摘要翻译： 一种治疗或预防通过催产素作用介导的疾病或病症的方法，其包括向有需要的人施用有效量的式（I）化合物或其药学上可接受的盐。
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