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公开(公告)号:US20130123537A1
公开(公告)日:2013-05-16
申请号:US13261518
申请日:2011-05-16
Applicant: K a s s Narayan Garimella , Subba Reddy Danda , Shankar Reddy Budidet , Srinivasachary Katuroju , Gowrisankar Rao Kaki , Srinivasa Rao Yatcherla , Islam Aminul , Sivakumaran Meenakshisunderam
Inventor: K a s s Narayan Garimella , Subba Reddy Danda , Shankar Reddy Budidet , Srinivasachary Katuroju , Gowrisankar Rao Kaki , Srinivasa Rao Yatcherla , Islam Aminul , Sivakumaran Meenakshisunderam
IPC: C07C231/12
CPC classification number: C07C231/12 , C07C231/24 , C07C237/22
Abstract: The present invention relates to an improved process for the preparation of Lacosamide of Formula (I), comprising: O-methylating a compound of Formula (V) or a compound of Formula (XX) or a compound of Formula XXII; in the presence of a methylating agent and a base to produce Lacosamide of Formula (I).
Abstract translation: 本发明涉及一种制备式(I)的拉科酰胺的改进方法,其包括:使式(Ⅴ)化合物或式(ⅩⅩ)化合物或式ⅩⅩⅫ化合物O-甲基化; 在甲基化剂和碱的存在下制备式(I)的拉科酰胺。
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公开(公告)号:US20070173645A1
公开(公告)日:2007-07-26
申请号:US11655027
申请日:2007-01-18
Applicant: Subba Reddy Danda , Narayan K.A.S.S. Garimella , Srinivasa Rao V.N Divvela , Ramesh Dandala , Sivakumaran Meenakshisunderam
Inventor: Subba Reddy Danda , Narayan K.A.S.S. Garimella , Srinivasa Rao V.N Divvela , Ramesh Dandala , Sivakumaran Meenakshisunderam
IPC: C07F9/6506 , C07F9/28 , C07F9/58
CPC classification number: C07F9/3873 , C07F9/386 , C07F9/58 , C07F9/6506 , C07F9/6561
Abstract: An improved process for bisphosphonylation of acids, substituted acids to obtain compounds with the formula using phosphorus trihalide, phosphorus acid, in presence of phenolic compounds as diluent/solvent.
Abstract translation: 在酚类化合物作为稀释剂/溶剂的存在下,改进了酸,取代酸的双膦酰化,得到具有下式的化合物的方法:磷三卤化磷,磷酸。
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公开(公告)号:US20170334838A1
公开(公告)日:2017-11-23
申请号:US15525564
申请日:2015-11-09
Applicant: Shankar Reddy Budidet , Jagan Mohan Reddy Sanapureddy , Subba Reddy Danda , Bhima Shankar Gangadhara , Somappa Somannavar Yallappa , Kishore Karumanchi , Sivakumaran Meenakshisunderam
Inventor: Shankar Reddy Budidet , Jagan Mohan Reddy Sanapureddy , Subba Reddy Danda , Bhima Shankar Gangadhara , Somappa Somannavar Yallappa , Kishore Karumanchi , Sivakumaran Meenakshisunderam
IPC: C07C253/30 , C07D273/02 , A61K31/513 , A61K31/506 , B01D11/02 , C07D413/12 , C07D239/54
CPC classification number: C07C253/30 , A61K31/506 , A61K31/513 , A61K2300/00 , B01D11/02 , C07C269/04 , C07C269/06 , C07D239/54 , C07D239/557 , C07D273/02 , C07D413/12 , C07C255/25 , C07C271/22 , C07C271/20
Abstract: The present invention provides a process for the preparation of crystalline anhydrous compound of Formula (X), Further, the present invention relates to the use of compound of Formula (X) preparation of Raltegravir (I) or its pharmaceutically acceptable salt thereof.
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公开(公告)号:US10259778B2
公开(公告)日:2019-04-16
申请号:US15525564
申请日:2015-11-09
Applicant: Shankar Reddy Budidet , Jagan Mohan Reddy Sanapureddy , Subba Reddy Danda , Bhima Shankar Gangadhara , Somappa Somannavar Yallappa , Kishore Karumanchi , Sivakumaran Meenakshisunderam
Inventor: Shankar Reddy Budidet , Jagan Mohan Reddy Sanapureddy , Subba Reddy Danda , Bhima Shankar Gangadhara , Somappa Somannavar Yallappa , Kishore Karumanchi , Sivakumaran Meenakshisunderam
IPC: C07C253/30 , C07D273/02 , A61K31/513 , A61K31/506 , B01D11/02 , C07D413/12 , C07D239/54 , C07C269/04 , C07C269/06 , C07D239/557
Abstract: The present invention provides a process for the preparation of crystalline anhydrous compound of Formula (X), Further, the present invention relates to the use of compound of Formula (X) preparation of Raltegravir (I) or its pharmaceutically acceptable salt thereof.
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公开(公告)号:US07528280B2
公开(公告)日:2009-05-05
申请号:US11655027
申请日:2007-01-18
Applicant: Subba Reddy Danda , Narayan K. A. S. S. Garimella , Srinivasa Rao V. N Divvela , Ramesh Dandala , Sivakumaran Meenakshisunderam
Inventor: Subba Reddy Danda , Narayan K. A. S. S. Garimella , Srinivasa Rao V. N Divvela , Ramesh Dandala , Sivakumaran Meenakshisunderam
IPC: C07F9/38
CPC classification number: C07F9/3873 , C07F9/386 , C07F9/58 , C07F9/6506 , C07F9/6561
Abstract: An improved process for bisphosphonylation of acids, substituted acids to obtain compounds with the formula using phosphorus trihalide, phosphorus acid, in presence of phenolic compounds as diluent/solvent.
Abstract translation: 在酚类化合物作为稀释剂/溶剂的存在下,改进了酸,取代酸的双膦酰化,得到具有下式的化合物的方法:磷三卤化磷,磷酸。
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