公开(公告)号：US20130303780A1

公开(公告)日：2013-11-14

申请号：US13883843

申请日：2011-11-03

Applicant: Siva Rama Prasad Vellanki ,  Arabinda Sahu ,  Satyanarayana Raavi ,  Ravi Nuchu ,  Ramesh Dandala

Inventor： Siva Rama Prasad Vellanki ,  Arabinda Sahu ,  Satyanarayana Raavi ,  Ravi Nuchu ,  Ramesh Dandala

IPC: C07D277/56

CPC classification number: C07D277/56

Abstract: The present invention relates an improved process for the preparation of 2-arylthiazole derivatives which are intermediates of Febuxostat and further conversion to Febuxostat or pharmaceutically acceptable salts thereof.

Abstract translation: 本发明涉及一种制备2-芳基噻唑衍生物的改进方法，它是非焦ost素的中间体，并进一步转化成非索非泮或其药学上可接受的盐。

公开(公告)号：US20100056797A1

公开(公告)日：2010-03-04

申请号：US11795896

申请日：2007-04-23

Applicant: Venkata vara prasada rao Korrapati ,  Venkata subramanyeswara rao Inti ,  Rani Ananta ,  Ramesh Dandala ,  Sivakumaran Meenakshisunderam

Inventor： Venkata vara prasada rao Korrapati ,  Venkata subramanyeswara rao Inti ,  Rani Ananta ,  Ramesh Dandala ,  Sivakumaran Meenakshisunderam

IPC: C07D257/04

CPC classification number: C07C231/06 ,  C07D403/10 ,  C07C237/30

Abstract: The present invention relates to an improved process for the preparation of 2-n-butyl-3-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]-1,3-diazaspiro[4.4]non-1-en-4-one (Irbesartan)

Abstract translation: 本发明涉及一种制备2-正丁基-3 - [[2' - （1H-四唑-5-基）[1,1'-联苯] -4-基] -1， 3-二氮杂螺[4.4]壬-1-烯-4-酮（厄贝沙坦）

公开(公告)号：US07528280B2

公开(公告)日：2009-05-05

申请号：US11655027

申请日：2007-01-18

Applicant: Subba Reddy Danda ,  Narayan K. A. S. S. Garimella ,  Srinivasa Rao V. N Divvela ,  Ramesh Dandala ,  Sivakumaran Meenakshisunderam

Inventor： Subba Reddy Danda ,  Narayan K. A. S. S. Garimella ,  Srinivasa Rao V. N Divvela ,  Ramesh Dandala ,  Sivakumaran Meenakshisunderam

IPC: C07F9/38

CPC classification number: C07F9/3873 ,  C07F9/386 ,  C07F9/58 ,  C07F9/6506 ,  C07F9/6561

Abstract: An improved process for bisphosphonylation of acids, substituted acids to obtain compounds with the formula using phosphorus trihalide, phosphorus acid, in presence of phenolic compounds as diluent/solvent.

Abstract translation: 在酚类化合物作为稀释剂/溶剂的存在下，改进了酸，取代酸的双膦酰化，得到具有下式的化合物的方法：磷三卤化磷，磷酸。

公开(公告)号：US08236991B2

公开(公告)日：2012-08-07

申请号：US12451872

申请日：2008-06-05

Applicant: V Raghava Reddy Ambati ,  Srinivas Garaga ,  Ramesh Dandala ,  Sivakumaran Meenakshisunderam

Inventor： V Raghava Reddy Ambati ,  Srinivas Garaga ,  Ramesh Dandala ,  Sivakumaran Meenakshisunderam

IPC: C07C21/00 ,  C07D277/22 ,  C07D277/28

CPC classification number: C07C213/10 ,  C07C215/28

Abstract: The present invention relates to the purification of (2S,3S,5S)-5-amino-2-N,N-dibenzylamino-3-hydroxy-1,6-diphenylhexane (III) by making its crystalline acid addition salt, which can be used as such to produce Lopinavir/Ritonavir with high purity and yield. Formula III

Abstract translation: 本发明涉及通过制备其结晶酸加成盐来纯化（2S，3S，5S）-5-氨基-2-N，N-二苄基氨基-3-羟基-1,6-二苯基己烷（III），其可以 用于生产具有高纯度和产率的洛匹那韦/利托那韦。 公式三

公开(公告)号：US20100125137A1

公开(公告)日：2010-05-20

申请号：US12451600

申请日：2008-05-14

Applicant: Jagan mohan Reddy Sanapureddy ,  Ramesh Dandala ,  Sivakumaran Meenakshisunderam

Inventor： Jagan mohan Reddy Sanapureddy ,  Ramesh Dandala ,  Sivakumaran Meenakshisunderam

IPC: C07D471/14 ,  C07D401/12

CPC classification number: C07D401/12 ,  C07D471/14

Abstract: An improved process for preparing 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one of Formula (I).

Abstract translation: 制备式（10）的11-环丙基-5,11-二氢-4-甲基-6H-二吡啶并[3,2-b：2'，3'-e] [1,4]二氮杂-6-酮的改进方法 一世）。

公开(公告)号：US20100029940A1

公开(公告)日：2010-02-04

申请号：US12448270

申请日：2007-12-11

Applicant: Ramesh Dandala ,  Sambhu Prasad Sarma Mallela ,  Sukumar Nandi ,  Gangadhar Bhima Shankar Nangi ,  Sunil Kumar Buridipadu ,  Sivakumaran Meenakshisunderam

Inventor： Ramesh Dandala ,  Sambhu Prasad Sarma Mallela ,  Sukumar Nandi ,  Gangadhar Bhima Shankar Nangi ,  Sunil Kumar Buridipadu ,  Sivakumaran Meenakshisunderam

IPC: C07D239/42

CPC classification number: C07D239/42

Abstract: The present invention relates to an improved process for preparing (2E)-3-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-propenal of Formula I which is an intermediate useful in the preparation of bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methyl-sulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoicacid] calcium salt of Formula II

Abstract translation: 本发明涉及制备式（2E）-3- [4-（4-氟苯基）-6-异丙基-2-（N-甲基-N-甲磺酰氨基）嘧啶-5-基] - 丙酸的方法， 其是可用于制备双[（E）-7- [4-（4-氟苯基）-6-异丙基-2- [甲基 - （磺酰基）氨基]嘧啶-5-基]（3R ，5S）-3,5-二羟基庚-6-烯酸]钙盐

公开(公告)号：US20070191610A1

公开(公告)日：2007-08-16

申请号：US11703948

申请日：2007-02-08

Applicant: Mahesh Nagarimadugu ,  Arun Gupta ,  Ramesh Dandala ,  Sivakumaran Meenakshisunderam

Inventor： Mahesh Nagarimadugu ,  Arun Gupta ,  Ramesh Dandala ,  Sivakumaran Meenakshisunderam

IPC: C07D211/06

CPC classification number: C07D211/32

Abstract: The present invention relates to an improved process for the preparation of 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride of Formula I.

Abstract translation: 本发明涉及制备式I的1-苄基-4 - [（5,6-二甲氧基-1-茚满酮）-2-基]甲基哌啶盐酸盐的改进方法。

公开(公告)号：US07164022B2

公开(公告)日：2007-01-16

申请号：US11252860

申请日：2005-10-18

Applicant: Ramesh Dandala ,  Divvela Venkata Naga Srinvasa Rao ,  Koilpillai Joseph Prabahar ,  Gollapalli Venkateswara Rao ,  Meenakshisunderam Sivakumaran

Inventor： Ramesh Dandala ,  Divvela Venkata Naga Srinvasa Rao ,  Koilpillai Joseph Prabahar ,  Gollapalli Venkateswara Rao ,  Meenakshisunderam Sivakumaran

IPC: C07D221/18 ,  C07D221/04

CPC classification number: C07D221/18

Abstract: The present invention relates to an improved process for the preparation of pure Finasteride of Formula I, which comprises converting dihydrofinasteride to finasteride through novel protected dihydrofinasteride and protected finasteride intermediates.

Abstract translation: 本发明涉及一种制备式I的纯非那雄胺的改进方法，其包括通过新型受保护的二氢芬西酰头孢甾酮和受保护的非那雄胺中间体将二氢芬太昔妥转化为非那雄胺。

公开(公告)号：US08492551B2

公开(公告)日：2013-07-23

申请号：US12451871

申请日：2008-05-30

Applicant: Shankar Reddy Budidet ,  Brajesh Kumar Sinha ,  Somappa Somannavar Yallappa ,  Senthil Kumar Natarajan ,  Ramesh Dandala ,  Sivakumaran Meenakshisunderam

Inventor： Shankar Reddy Budidet ,  Brajesh Kumar Sinha ,  Somappa Somannavar Yallappa ,  Senthil Kumar Natarajan ,  Ramesh Dandala ,  Sivakumaran Meenakshisunderam

IPC: C07D401/12

CPC classification number: C07D401/12

Abstract: An improved process for the preparation of (S)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole of Formula I, (I) with high enantiomeric excess from racemic mixture.

Abstract translation: 一种制备式（I）的（S）-5-甲氧基-2 - [[（4-甲氧基-3,5-二甲基-2-吡啶基）甲基]亚磺酰基] -1H-苯并咪唑的方法， 来自外消旋混合物的高对映体过量。

公开(公告)号：US20100130744A1

公开(公告)日：2010-05-27

申请号：US12451775

申请日：2008-05-29

Applicant: Mahesh Nagarimadugu ,  Vipin Kumar Kaushik ,  Ramesh Dandala ,  Sivakumaran Meenakshisunderam

Inventor： Mahesh Nagarimadugu ,  Vipin Kumar Kaushik ,  Ramesh Dandala ,  Sivakumaran Meenakshisunderam

IPC: C07D401/12

CPC classification number: C07D215/227

Abstract: The present invention relates to an improved process for the preparation of 7-[4-[4-(2,3-dichlorophenyl)-1-piper-azinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone of Formula (I).

Abstract translation: 本发明涉及制备7- [4- [4-（2,3-二氯苯基）-1-哌嗪基]丁氧基] -3,4-二氢-2（1H） - 喹啉酮的改进方法 式（I）。