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1.发明授权Compositions and methods for treating, reducing, ameliorating, or preventing infections 有权用于治疗，减少，改善或预防感染的组合物和方法公开(公告)号：US08173640B1
公开(公告)日：2012-05-08
申请号：US12115914
申请日：2008-05-06
申请人： Praveen Tyle , Erning Xia , Honga Wang , Susan E. Norton , Pramod Kumar Gupta , Keith W. Ward , Lynne Brunner
发明人： Praveen Tyle , Erning Xia , Honga Wang , Susan E. Norton , Pramod Kumar Gupta , Keith W. Ward , Lynne Brunner
IPC分类号： A61K31/55 , A61K39/40 , C07D243/08
CPC分类号： A61K45/06 , A61K31/55 , A61K2300/00
摘要： Compositions for treating, reducing, ameliorating, or preventing infections comprise a fluoroquinolone having Formulae I-VIII and an additional anti-infective agent. Methods for treating, reducing, ameliorating, or preventing such infection use such compositions. Such compositions and methods can be effective against mixed types of pathogens including certain antibiotic-resistant microbial pathogens found in such infections.
摘要翻译： 用于治疗，减少，改善或预防感染的组合物包含具有式I-VIII和另外的抗感染剂的氟喹诺酮。 治疗，减轻，改善或预防这种感染的方法使用这种组合物。 这种组合物和方法可以有效地对抗混合类型的病原体，包括在这种感染中发现的某些抗生素抗性微生物病原体。
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2.发明授权公开(公告)号：US08415342B2
公开(公告)日：2013-04-09
申请号：US12604422
申请日：2009-10-23
CPC分类号： A61K31/55
摘要： A composition comprises besifloxacin in an amount effective for treating or controlling an infection caused by an antibiotic-resistant bacterium. Such a composition can be administered to a subject for the treatment or control of bacterial conjunctivitis caused bay an antibiotic-resistant bacterium.
摘要翻译： 组合物包含对治疗或控制由抗生素抗性细菌引起的感染有效量的贝沙星。 这种组合物可以施用于受试者，用于治疗或控制引起抗生素抗性细菌的细菌性结膜炎。
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公开(公告)号：US08334283B2
公开(公告)日：2012-12-18
申请号：US13437965
申请日：2012-04-03
申请人： Praveen Tyle , Erning Xia , Hongna Wang , Susan E. Norton , Pramod Kumar Gupta , Keith W. Ward , Lynne Brunner
发明人： Praveen Tyle , Erning Xia , Hongna Wang , Susan E. Norton , Pramod Kumar Gupta , Keith W. Ward , Lynne Brunner
IPC分类号： A61K31/55 , A61K39/40 , C07D243/08
CPC分类号： A61K45/06 , A61K31/55 , A61K2300/00
摘要： Compositions for treating, reducing, ameliorating, or preventing infections comprise a fluoroquinolone having Formulae I-VIII and an additional anti-infective agent. Methods for treating, reducing, ameliorating, or preventing such infection use such compositions. Such compositions and methods can be effective against mixed types of pathogens including certain antibiotic-resistant microbial pathogens found in such infections.
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4.发明申请公开(公告)号：US20080261900A1
公开(公告)日：2008-10-23
申请号：US12051289
申请日：2008-03-19
IPC分类号： A61K31/7042 , C07D401/00 , C07D243/08 , A61K31/55 , A61P31/04 , A61K31/551 , A61K31/56 , A61K31/43
CPC分类号： A61K31/55
摘要： Compositions comprise a fluoroquinolone having Formulae I-VIII for treating, reducing, ameliorating, or preventing infections caused by some bacteria that are resistant to an antibacterial drug. Methods for treating, reducing, ameliorating, or preventing such infections use such compositions.
摘要翻译： 组合物包含具有式I-VIII的氟喹诺酮，用于治疗，减少，改善或预防由抗细菌药物抗性的一些细菌引起的感染。 治疗，减轻，改善或预防这种感染的方法使用这种组合物。
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5.发明申请Compositions and Methods for Treating, Reducing, Ameliorating, or Preventing Infections 有权治疗，减少，改善或预防感染的组合物和方法公开(公告)号：US20120196840A1
公开(公告)日：2012-08-02
申请号：US13437965
申请日：2012-04-03
申请人： Praveen Tyle , Erning Xia , Hongna Wang , Susan E. Norton , Pramod Kumar Gupta , Keith W. Ward , Lynne Brunner
发明人： Praveen Tyle , Erning Xia , Hongna Wang , Susan E. Norton , Pramod Kumar Gupta , Keith W. Ward , Lynne Brunner
CPC分类号： A61K45/06 , A61K31/55 , A61K2300/00
摘要： Compositions for treating, reducing, ameliorating, or preventing infections comprise a fluoroquinolone having Formulae I-VIII and an additional anti-infective agent. Methods for treating, reducing, ameliorating, or preventing such infection use such compositions. Such compositions and methods can be effective against mixed types of pathogens including certain antibiotic-resistant microbial pathogens found in such infections.
摘要翻译： 用于治疗，减少，改善或预防感染的组合物包含具有式I-VIII和另外的抗感染剂的氟喹诺酮。 治疗，减轻，改善或预防这种感染的方法使用这种组合物。 这种组合物和方法可以有效地对抗混合类型的病原体，包括在这种感染中发现的某些抗生素抗性微生物病原体。
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6.发明申请Besifloxacin Ophthalmic Composition for the Treatment or Control of Infection 有权用于治疗或控制感染的贝西沙星眼科组合物公开(公告)号：US20100105662A1
公开(公告)日：2010-04-29
申请号：US12604422
申请日：2009-10-23
IPC分类号： A61K31/55
CPC分类号： A61K31/55
摘要： A composition comprises besifloxacin in an amount effective for treating or controlling an infection caused by an antibiotic-resistant bacterium. Such a composition can be administered to a subject for the treatment or control of bacterial conjunctivitis caused bay an antibiotic-resistant bacterium.
摘要翻译： 组合物包含对治疗或控制由抗生素抗性细菌引起的感染有效量的贝沙星。 这种组合物可以施用于受试者，用于治疗或控制引起抗生素抗性细菌的细菌性结膜炎。
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7.发明授权Compositions and methods for treating, reducing, ameliorating, or preventing infections caused by antibacterial drug-resistant bacteria 有权用于治疗，减少，改善或预防由抗菌耐药性细菌引起的感染的组合物和方法公开(公告)号：US08937062B2
公开(公告)日：2015-01-20
申请号：US12051289
申请日：2008-03-19
CPC分类号： A61K31/55
摘要： Compositions comprise a fluoroquinolone having Formulae I-VIII for treating, reducing, ameliorating, or preventing infections caused by some bacteria that are resistant to an antibacterial drug. Methods for treating, reducing, ameliorating, or preventing such infections use such compositions.
摘要翻译： 组合物包含具有式I-VIII的氟喹诺酮，用于治疗，减少，改善或预防由抗细菌药物抗性的一些细菌引起的感染。 治疗，减轻，改善或预防这种感染的方法使用这种组合物。
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