Novel glycoproteins and methods of use thereof
    1.
    发明申请
    Novel glycoproteins and methods of use thereof 审中-公开
    新型糖蛋白及其使用方法

    公开(公告)号:US20050095676A1

    公开(公告)日:2005-05-05

    申请号:US10913944

    申请日:2004-08-06

    摘要: The present invention provides novel isolated ARP/BRP polynucleotides and the membrane-associated or secreted polypeptides encoded by the ARP/BRP polynucleotides. Also provided are ARP and BRP protein multimers. Further provided are the antibodies that immunospecifically bind to a ARP/BRP polypeptide or any derivative, variant, mutant or fragment of the ARP/BRP polypeptide, a ARP/BRP multimer polynucleotide or antibody. The invention additionally provides methods in which the ARP/BRP polypeptide, multimer, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, e.g. reproductive disorder, as well as to other uses.

    摘要翻译: 本发明提供新的分离的ARP / BRP多核苷酸和由ARP / BRP多核苷酸编码的膜相关或分泌的多肽。 还提供了ARP和BRP蛋白多聚体。 还提供免疫特异性结合ARP / BRP多肽或ARP / BRP多肽的任何衍生物,变体,突变体或片段,ARP / BRP多聚体多核苷酸或抗体的抗体。 本发明还提供了其中使用ARP / BRP多肽,多聚体,多核苷酸和抗体来检测和治疗广泛的病理状态的方法,例如, 生殖障碍,以及其他用途。