Oral dosage and method for treating painful conditions of the oral cavity
    7.
    发明授权
    Oral dosage and method for treating painful conditions of the oral cavity 失效
    口腔用量和治疗口腔疼痛病症的方法

    公开(公告)号:US5713852A

    公开(公告)日:1998-02-03

    申请号:US475233

    申请日:1995-06-07

    CPC分类号: A61K9/0004

    摘要: A method is described for delivering a beneficial agent, such as an antiinflammatory agent, to the site of a painful condition in the oral cavity of a human being that utilizes an oral dosage form having an immediately releasable topical anesthetic and a sustained release beneficial agent. The topical anesthetic is released substantially independently of the beneficial agent to provide immediate pain relief and the application of the beneficial agent is continued over a long period of time.

    摘要翻译: 描述了一种用于将有益药物(例如抗炎剂)递送到使用具有立即可释放的局部麻醉剂和持续释放有益剂的口服剂型的人口腔中的疼痛状况的部位的方法。 局部麻醉剂基本上独立于有益药物释放,以立即缓解疼痛,并且长期持续有益药物的应用。

    Injectable drug delivery system and method
    8.
    发明授权
    Injectable drug delivery system and method 失效
    注射药物递送系统及方法

    公开(公告)号:US5620700A

    公开(公告)日:1997-04-15

    申请号:US437471

    申请日:1995-05-09

    IPC分类号: A61C19/06 A61K6/00 A61K47/34

    CPC分类号: A61C19/063 A61K47/34

    摘要: The present invention is directed to a material which can be used to deliver a drug, such as an antibiotic, into a diseased tissue pocket, such as a periodontal pocket. The material is preferably a bioerodible oligomer or polymer. The oligomer or polymer containing the drug is heated and is then delivered, preferably by injection, into the tissue pocket at a physiologically compatible elevated temperature. Once the bioerodible material is injected into the pocket, the material cools to the body temperature of the pocket. As it cools, the material hardens and remains in place in the tissue pocket. The hardened material bioerodes in the pocket and releases the drug over a period of several days.

    摘要翻译: 本发明涉及可用于将诸如抗生素的药物递送到患病组织袋(例如牙周袋)中的材料。 该材料优选为生物可腐蚀的低聚物或聚合物。 包含药物的低聚物或聚合物被加热,然后优选通过注射递送到生理上相容的升高的温度下的组织袋中。 一旦将生物可蚀解材料注入到口袋中,则该材料冷却到口袋的体温。 当它冷却时,材料硬化并保持在组织袋中的适当位置。 硬化的材料在口袋中传播并在几天的时间内释放药物。

    Injectable drug delivery system and method
    9.
    发明授权
    Injectable drug delivery system and method 失效
    注射药物递送系统及方法

    公开(公告)号:US5783205A

    公开(公告)日:1998-07-21

    申请号:US843682

    申请日:1997-04-10

    摘要: The present invention is directed to a material which can be used to deliver a drug, such as an antibiotic, into a diseased tissue pocket, such as a periodontal pocket. The material is preferably a bioerodible oligomer or polymer. The oligomer or polymer containing the drug is heated and is then delivered, preferably by injection, into the tissue pocket at a physiologically compatible elevated temperature. Once the bioerodible material is injected into the pocket, the material cools to the body temperature of the pocket. As it cools, the material hardens and remains in place in the tissue pocket. The hardened material bioerodes in the pocket and releases the drug over a period of several days.

    摘要翻译: 本发明涉及可用于将诸如抗生素的药物递送到患病组织袋(例如牙周袋)中的材料。 该材料优选为生物可腐蚀的低聚物或聚合物。 包含药物的低聚物或聚合物被加热,然后优选通过注射递送到生理上相容的升高的温度下的组织袋中。 一旦将生物可蚀解材料注入到口袋中,则该材料冷却到口袋的体温。 当它冷却时,材料硬化并保持在组织袋中的适当位置。 硬化的材料在口袋中传播并在几天的时间内释放药物。