公开(公告)号：US3038786A

公开(公告)日：1962-06-12

申请号：US85983759

申请日：1959-12-16

Applicant: KIZO HIRATSUKA ,  SHIRO MATSUMURA ,  MASATSNGI MATSNDA ,  KIYOSHI TAKAGI ,  ZENICHIRO KASAWARA ,  TADAO OONO ,  TETSUYA ABE ,  NORIAKI OZAWA

Inventor： KIZO HIRATSUKA ,  SHIRO MATSUMURA ,  MASATSNGI MATSNDA ,  KIYOSHI TAKAGI ,  ZENICHIRO KASAWARA ,  TADAO OONO ,  TETSUYA ABE ,  NORIAKI OZAWA

IPC: C01B15/023

CPC classification number: C01B15/023

公开(公告)号：US5254462A

公开(公告)日：1993-10-19

申请号：US714639

申请日：1991-06-13

Applicant: Tadao Oono ,  Kaoru Saijo ,  Junko Kurashima

Inventor： Tadao Oono ,  Kaoru Saijo ,  Junko Kurashima

IPC: C12N5/10 ,  C07K14/025 ,  C07K14/61 ,  C12N5/06 ,  C12N15/09 ,  C12N15/18 ,  C12N15/37 ,  C12N15/85 ,  C12P21/02 ,  C12R1/91 ,  C12N15/63

CPC classification number: C07K14/005 ,  C07K14/61 ,  C12N15/85 ,  C12N2710/22022 ,  C12N2800/108 ,  C12N2830/002 ,  C12N2830/85

Abstract: The present invention relates to an animal cell line which is capable of growing in a substantially protein-free medium and has a substance capable of enhancing replication of exogenous genes.The animal cell line according to the present invention can grow in a substantially protein-free medium and can replicate exogenous genes extrachromosomally. It is possible to easily produce a great amount of substances useful to mammals by using the transformant according to the present invention. Further, it is easy to collect and purify the substances useful to mammals, which are produced by using the transformant according to the present invention.