公开(公告)号：US20210275200A1

公开(公告)日：2021-09-09

申请号：US17215518

申请日：2021-03-29

Applicant: Thrombolex, Inc

Inventor： Nicholas Green

IPC: A61B17/221 ,  A61B18/24 ,  A61B5/00 ,  A61B5/107

Abstract: The present disclosure relates to a basket for a catheter designed to be deployed in complex vasculature to optimally treat vascular and arterial disease conditions such as blood clots, blood emboli, and deep vein thrombosis. The basket may comprise a shaft with a plurality of cuts along a portion of its length to form a plurality of tines that provide support for a plurality of porous tubes to form the limbs of the basket. The limbs of the basket expand radially away from the longitudinal axis of the basket when the longitudinal length of the basket is reduced. The limbs may also be connected to a drug delivery system, and in this manner, baskets of the present disclosure allow for the use of both mechanical and pharmaceutical means of thrombolysis.

公开(公告)号：US12245784B2

公开(公告)日：2025-03-11

申请号：US18392152

申请日：2023-12-21

Applicant: Thrombolex, Inc.

Inventor： Nicholas Green

IPC: A61B17/221 ,  A61B5/00 ,  A61B5/107 ,  A61B18/24 ,  A61B17/00 ,  A61B17/22 ,  A61B18/00 ,  A61B18/22 ,  A61B90/00 ,  A61N5/06

Abstract: The present disclosure relates to a basket for a catheter designed to be deployed in complex vasculature to optimally treat vascular and arterial disease conditions such as blood clots, blood emboli, and deep vein thrombosis. The basket may comprise a shaft with a plurality of cuts along a portion of its length to form a plurality of tines that provide support for a plurality of porous tubes to form the limbs of the basket. The limbs of the basket expand radially away from the longitudinal axis of the basket when the longitudinal length of the basket is reduced. The limbs may also be connected to a drug delivery system, and in this manner, baskets of the present disclosure allow for the use of both mechanical and pharmaceutical means of thrombolysis.

公开(公告)号：US20240122614A1

公开(公告)日：2024-04-18

申请号：US18392152

申请日：2023-12-21

Applicant: Thrombolex, Inc.

Inventor： Nicholas Green

IPC: A61B17/221 ,  A61B5/00 ,  A61B5/107 ,  A61B18/24

CPC classification number: A61B17/221 ,  A61B5/00 ,  A61B5/1076 ,  A61B5/6858 ,  A61B18/245 ,  A61B2017/00867

Abstract: The present disclosure relates to a basket for a catheter designed to be deployed in complex vasculature to optimally treat vascular and arterial disease conditions such as blood clots, blood emboli, and deep vein thrombosis. The basket may comprise a shaft with a plurality of cuts along a portion of its length to form a plurality of tines that provide support for a plurality of porous tubes to form the limbs of the basket. The limbs of the basket expand radially away from the longitudinal axis of the basket when the longitudinal length of the basket is reduced. The limbs may also be connected to a drug delivery system, and in this manner, baskets of the present disclosure allow for the use of both mechanical and pharmaceutical means of thrombolysis.

公开(公告)号：US20210170148A1

公开(公告)日：2021-06-10

申请号：US17159435

申请日：2021-01-27

Applicant: Thrombolex, Inc

Inventor： Nicholas Green ,  Samuel Evans

IPC: A61M25/10 ,  A61M25/00

Abstract: The present disclosure relates to catheter system comprising a balloon and an infusion basket designed to be deployed in complex vasculature to optimally treat vascular and arterial disease conditions such as blood clots, blood emboli, and deep vein thrombosis. The basket may comprise a shaft with a plurality of cuts along a portion of its length to form a plurality of tines that provide support for a plurality of porous tubes to form the limbs of the basket. The limbs of the basket expand radially away from the longitudinal axis of the basket when the longitudinal length of the basket is reduced. The limbs may also be connected to a drug delivery system, and in this manner, baskets of the present disclosure allow for the use of both mechanical and pharmaceutical means of thrombolysis and thrombectomy.

公开(公告)号：US20240058026A1

公开(公告)日：2024-02-22

申请号：US18498210

申请日：2023-10-31

Applicant: Temple University-Of The Commonwealth System of Higher Education ,  Thrombolex, Inc.

Inventor： Riyaz Bashir ,  Nicholas A. Green

IPC: A61B17/221 ,  A61B17/22 ,  A61B18/00 ,  A61M25/00 ,  A61M25/01

CPC classification number: A61B17/221 ,  A61B17/22 ,  A61B18/00 ,  A61M25/0043 ,  A61M25/007 ,  A61M25/0108 ,  A61B2017/22084 ,  A61B2017/2217 ,  A61B17/320725 ,  A61M25/0074 ,  A61M2205/0266

Abstract: An infusion catheter has an elongate flexible shaft including a wall and a lumen extending between a proximal end and a distal end. The catheter also has a sealing member within the shaft lumen including a wall and a lumen. The catheter also has a slidable, retractable elongate central axis member extending through the shaft and sealing member lumens connected to an end cap. The catheter also has a plurality of eluting arms extending radially around the central axis member, including lumens fluidly connected to the shaft lumen and the distal end cap. A method for treating a thrombus is also disclosed.

公开(公告)号：US11826065B2

公开(公告)日：2023-11-28

申请号：US17222588

申请日：2021-04-05

Applicant: Temple University—Of The Commonwealth System of Higher Education ,  THROMBOLEX, INC.

Inventor： Riyaz Bashir ,  Nicholas A. Green

IPC: A61M25/00 ,  A61B17/22 ,  A61B17/221 ,  A61B18/00 ,  A61M25/01 ,  A61B17/3207 ,  A61B17/00

CPC classification number: A61B17/221 ,  A61B17/22 ,  A61B18/00 ,  A61M25/007 ,  A61M25/0043 ,  A61M25/0108 ,  A61B17/320725 ,  A61B2017/00871 ,  A61B2017/2217 ,  A61B2017/22038 ,  A61B2017/22084 ,  A61M25/0074 ,  A61M2025/0057 ,  A61M2205/0266

Abstract: An infusion catheter has an elongate flexible shaft including a wall and a lumen extending between a proximal end and a distal end. The catheter also has a sealing member within the shaft lumen including a wall and a lumen. The catheter also has a slidable, retractable elongate central axis member extending through the shaft and sealing member lumens connected to an end cap. The catheter also has a plurality of eluting arms extending radially around the central axis member, including lumens fluidly connected to the shaft lumen and the distal end cap. A method for treating a thrombus is also disclosed.

公开(公告)号：US11883044B2

公开(公告)日：2024-01-30

申请号：US17215518

申请日：2021-03-29

Applicant: Thrombolex, Inc

Inventor： Nicholas Green

IPC: A61B17/221 ,  A61B18/24 ,  A61B5/00 ,  A61B5/107 ,  A61B17/00 ,  A61B17/22 ,  A61N5/06 ,  A61B18/00 ,  A61B18/22 ,  A61B90/00

CPC classification number: A61B17/221 ,  A61B5/00 ,  A61B5/1076 ,  A61B5/6858 ,  A61B18/245 ,  A61B2017/00867 ,  A61B2017/2212 ,  A61B2017/2215 ,  A61B2017/22084 ,  A61B2017/22085 ,  A61B2017/22087 ,  A61B2018/00029 ,  A61B2018/0041 ,  A61B2018/00267 ,  A61B2018/2211 ,  A61B2090/064 ,  A61B2217/007 ,  A61N5/062 ,  A61N2005/063

Abstract: The present disclosure relates to a basket for a catheter designed to be deployed in complex vasculature to optimally treat vascular and arterial disease conditions such as blood clots, blood emboli, and deep vein thrombosis. The basket may comprise a shaft with a plurality of cuts along a portion of its length to form a plurality of tines that provide support for a plurality of porous tubes to form the limbs of the basket. The limbs of the basket expand radially away from the longitudinal axis of the basket when the longitudinal length of the basket is reduced. The limbs may also be connected to a drug delivery system, and in this manner, baskets of the present disclosure allow for the use of both mechanical and pharmaceutical means of thrombolysis.

公开(公告)号：US20210236149A1

公开(公告)日：2021-08-05

申请号：US17222588

申请日：2021-04-05

Applicant: Temple University-Of The Commonwealth System of Higher Education ,  THROMBOLEX, INC.

Inventor： Riyaz Bashir ,  Nicholas A. Green

IPC: A61B17/221 ,  A61B17/22 ,  A61B18/00 ,  A61M25/00 ,  A61M25/01

Abstract: An infusion catheter has an elongate flexible shaft including a wall and a lumen extending between a proximal end and a distal end. The catheter also has a sealing member within the shaft lumen including a wall and a lumen. The catheter also has a slidable, retractable elongate central axis member extending through the shaft and sealing member lumens connected to an end cap. The catheter also has a plurality of eluting arms extending radially around the central axis member, including lumens fluidly connected to the shaft lumen and the distal end cap. A method for treating a thrombus is also disclosed.

公开(公告)号：US10973539B2

公开(公告)日：2021-04-13

申请号：US16165653

申请日：2018-10-19

Applicant: Thrombolex, Inc.

Inventor： Nicholas Green

IPC: A61B17/221 ,  A61B18/24 ,  A61B5/00 ,  A61B5/107 ,  A61B17/00 ,  A61B17/22 ,  A61N5/06 ,  A61B18/00 ,  A61B18/22 ,  A61B90/00

Abstract: The present disclosure relates to a basket for a catheter designed to be deployed in complex vasculature to optimally treat vascular and arterial disease conditions such as blood clots, blood emboli, and deep vein thrombosis. The basket may comprise a shaft with a plurality of cuts along a portion of its length to form a plurality of tines that provide support for a plurality of porous tubes to form the limbs of the basket. The limbs of the basket expand radially away from the longitudinal axis of the basket when the longitudinal length of the basket is reduced. The limbs may also be connected to a drug delivery system, and in this manner, baskets of the present disclosure allow for the use of both mechanical and pharmaceutical means of thrombolysis.

公开(公告)号：US20210085931A1

公开(公告)日：2021-03-25

申请号：US17032190

申请日：2020-09-25

Applicant: Thrombolex, Inc.

Inventor： Nicholas Green ,  Samuel Evans

IPC: A61M25/10 ,  A61M25/00

Abstract: The present disclosure relates to catheter system comprising a balloon and an infusion basket designed to be deployed in complex vasculature to optimally treat vascular and arterial disease conditions such as blood clots, blood emboli, and deep vein thrombosis. The basket may comprise a shaft with a plurality of cuts along a portion of its length to form a plurality of tines that provide support for a plurality of porous tubes to form the limbs of the basket. The limbs of the basket expand radially away from the longitudinal axis of the basket when the longitudinal length of the basket is reduced. The limbs may also be connected to a drug delivery system, and in this manner, baskets of the present disclosure allow for the use of both mechanical and pharmaceutical means of thrombolysis and thrombectomy.