公开(公告)号：US6149818A

公开(公告)日：2000-11-21

申请号：US386149

申请日：1999-08-31

申请人： Kenji Nakamura ,  Shinji Satomura ,  Masayoshi Hayashi ,  Hideyoshi Arashima ,  Tetsushi Okuyama ,  Nobuhiro Hanafusa ,  Koji Tanimizu

发明人： Kenji Nakamura ,  Shinji Satomura ,  Masayoshi Hayashi ,  Hideyoshi Arashima ,  Tetsushi Okuyama ,  Nobuhiro Hanafusa ,  Koji Tanimizu

IPC分类号： B01D15/08 ,  G01N30/16 ,  G01N30/24 ,  G01N30/40 ,  G01N30/88

CPC分类号： G01N30/40 ,  B01D15/1807 ,  B01D15/14 ,  G01N2030/402 ,  G01N2030/407 ,  G01N30/16 ,  G01N30/24 ,  G01N30/88

摘要： The object of the present invention is to provide a method for separating components in a liquid specimen and an apparatus used in said method, by which it is possible to avoid carryover even when the specimen injector is not washed using washing solution and also to avoid the increase of inner pressure in column of the separation device or ineffective separating operation even when many liquid specimens are separated by many times using the same separation device. In the present invention, the liquid specimen is introduced into the separation device from a direction opposite to eluting direction of the separation device which retains an adsorbent, and by separating and eluting the specimen from eluting outlet together with the eluant, trace quantity of insoluble substances and the specimen remained on the specimen introducing passage can be removed by elution procedure. As a result, it is possible to avoid carryover, to prevent the increase of inner pressure in the column of the separation device and to prevent ineffective separating operation caused by clogging of the column.

摘要翻译： 本发明的目的是提供一种用于分离液体试样中的组分和所述方法中使用的装置的方法，即使当使用洗涤溶液不洗涤试样注射器时也可以避免携带，并且避免 即使使用相同的分离装置多次分离多个液体样品，分离装置的塔内部压力增加或分离操作无效。 在本发明中，将液体试样从与保留吸附剂的分离装置的洗脱方向相反的方向引入分离装置，通过从洗脱液与洗脱液一起分离和洗脱试样，追踪微量的不溶物 残留在样品导入通道上的样品可以通过洗脱程序除去。 结果，可以避免残留，以防止分离装置的塔中的内压增加，并且防止由于柱的堵塞而导致的无效的分离操作。

公开(公告)号：US6156195A

公开(公告)日：2000-12-05

申请号：US48327

申请日：1998-03-26

申请人： Kenji Nakamura ,  Shinji Satomura ,  Masayoshi Hayashi ,  Hideyoshi Arashima ,  Tetsushi Okuyama ,  Nobuhiro Hanafusa ,  Koji Tanimizu

发明人： Kenji Nakamura ,  Shinji Satomura ,  Masayoshi Hayashi ,  Hideyoshi Arashima ,  Tetsushi Okuyama ,  Nobuhiro Hanafusa ,  Koji Tanimizu

IPC分类号： B01D15/08 ,  G01N30/16 ,  G01N30/24 ,  G01N30/40 ,  G01N30/88

CPC分类号： G01N30/40 ,  B01D15/1807 ,  B01D15/14 ,  G01N2030/402 ,  G01N2030/407 ,  G01N30/16 ,  G01N30/24 ,  G01N30/88

摘要： The object of the present invention is to provide a method for separating components in a liquid specimen and an apparatus used in said method, by which it is possible to avoid carryover even when the specimen injector is not washed using washing solution and also to avoid the increase of inner pressure in column of the separation device or ineffective separating operation even when many liquid specimens are separated by many times using the same separation device. In the present invention, the liquid specimen is introduced into the separation device from a direction opposite to eluting direction of the separation device which retains an adsorbent, and by separating and eluting the specimen from eluting outlet together with the eluant, trace quantity of insoluble substances and the specimen remained on the specimen introducing passage can be removed by elution procedure. As a result, it is possible to avoid carryover, to prevent the increase of inner pressure in the column of the separation device and to prevent ineffective separating operation caused by clogging of the column.