公开(公告)号：US20240167985A1

公开(公告)日：2024-05-23

申请号：US18493974

申请日：2023-10-25

申请人： DIONEX SOFTRON GMBH

发明人： Hermann HOCHGRAEBER

IPC分类号： G01N30/20 ,  G01N30/32 ,  G01N35/10

CPC分类号： G01N30/20 ,  G01N30/32 ,  G01N35/1097 ,  G01N2030/201 ,  G01N30/24

摘要： A sample injection method for liquid chromatography is performed with an injection valve having a waste port, two sample loop ports, and two high-pressure ports. One high-pressure port can be connected to a pump and the other high-pressure port can be connected to a chromatography column. A sample loop is connected to one of the sample loop ports on one end and to a pump volume of a sample conveying device on the other end. A section of the sample loop can be separated to facilitate receiving a sample fluid in the sample loop. A control unit controls the injection valve and the sample conveying device. The sample injector allows a sample to be loaded into the sample loop and then pressurized to an operating pressure prior to injecting the sample into the chromatography column. The sample loop may also be isolated from the operating pressure for facilitating depressurization of the loop.

公开(公告)号：US11988648B2

公开(公告)日：2024-05-21

申请号：US16760632

申请日：2018-07-25

申请人： Shimadzu Corporation

发明人： Daisuke Nakayama

IPC分类号： G01N30/24 ,  G01N30/34 ,  G01N30/02

CPC分类号： G01N30/24 ,  G01N30/34 ,  G01N2030/027

摘要： A liquid chromatograph includes: a feeding unit configured to feed a mobile phase prepared for an analysis; an analysis flow path provided with an analytical column for separating a sample and a detector for detecting sample components separated with the analytical column; a sample injection part configured to inject the sample into the analysis flow path; a measurement flow path provided separately from the analysis flow path and provided with a measuring instrument for measuring a preparation state of the mobile phase; and a status switching unit configured to selectively switch between an analysis state in which all of the mobile phase the from feeding unit flows through the analysis flow path and a measurement state in which at least a part of the mobile phase from the feeding unit flows through the measurement flow path.

公开(公告)号：US20240151694A1

公开(公告)日：2024-05-09

申请号：US18279822

申请日：2021-11-08

申请人： SHIMADZU CORPORATION

发明人： Soichiro TAMAOKI ,  Tomoyuki YAMAZAKI ,  Shohei SATO

IPC分类号： G01N30/24 ,  G01N30/02 ,  G01N30/82

CPC分类号： G01N30/24 ,  G01N30/82 ,  G01N2030/027

摘要： A separation channel on which a liquid delivery pump, a separation column, and a detector are provided, the liquid delivering pump being for feeding a mobile phase, the separation column being for separating a component in a sample, and the detector being for detecting peaks of components separated from each other by the separation column, a plurality of liquid handlers each including an injecting part and a collecting part, wherein when one of the plurality of liquid handlers is introduced into the separation channel, the injecting part of the one of the plurality of liquid handlers functions as an injector that executes injection operation of a sample into a mobile phase flowing through the analysis channel upstream of the separation column in the analysis channel and the collecting part of the one the plurality of liquid handlers functions as a fraction collector that executes collection operation of peaks of components separated from each other in the separation column, a selector for selectively switching a liquid handler to be introduced into the separation channel among a plurality of the liquid handlers, and a controller for controlling operation of a plurality of the liquid handlers and the selector.

公开(公告)号：US11965863B2

公开(公告)日：2024-04-23

申请号：US18070859

申请日：2022-11-29

申请人： Waters Technologies Corporation

发明人： Sylvain Gilles Cormier ,  Joseph D. Antocci ,  Francis Patrick Tracey ,  Charles H. Phoebe, Jr.

IPC分类号： G01N30/24 ,  G01N30/20 ,  G01N30/38 ,  G01N30/02

CPC分类号： G01N30/20 ,  G01N30/24 ,  G01N30/38 ,  G01N2030/027 ,  G01N2030/207

摘要： A liquid chromatography system includes a solvent delivery system, a sample manager including a sample delivery system in fluidic communication with the solvent delivery system, the sample delivery system configured to inject a sample from a sample-vial into a chromatographic flow stream, a liquid chromatography column located downstream from the sample delivery system, and a detector located downstream from the liquid chromatography column. The sample delivery system further includes a first needle drive including a first sample needle configured to extract the sample from the sample-vial and deliver the sample to the liquid chromatography column, and a first syringe in communication with the first sample needle configured to meter extraction of the sample from the sample-vial. The sample manager further includes a sample automation system that includes a second needle drive including a second sample needle configured to add a volume of reagent to the sample-vial.

公开(公告)号：US20240053305A1

公开(公告)日：2024-02-15

申请号：US17817604

申请日：2022-08-04

申请人： SAUDI ARABIAN OIL COMPANY

发明人： Mohamed Ahmed Saad Mahmoud ,  Ahmed Hamad Al-Salman ,  Hassan Yahya Al-Malki

IPC分类号： G01N30/24 ,  G01N30/30 ,  G01N30/14 ,  G01N30/68

CPC分类号： G01N30/24 ,  G01N30/30 ,  G01N30/14 ,  G01N30/68 ,  G01N2030/025

摘要： A method may include transporting a water stream comprising water and a biocide from an upstream location to a downstream location, withdrawing a sample of the water stream to a sample collection and analyses system, preconditioning the sample, injecting the preconditioned sample into an online gas chromatography analyzer, measuring a concentration of the biocide in the sample via the online gas chromatography analyzer to obtain a measurement result, transmitting the measurement result to a control system, and adjusting by the control system, automatically injecting biocide into the water stream at the upstream location based on the biocide dosage requirement on either a batch, or semi-batch, or a continuous basis. A system for measuring and controlling biocide concentration in a water stream in a pipeline may include a sample probe, a cabinet heater, a filtering unit, an online gas chromatography analyzer, a control system, and an injection system.

公开(公告)号：US20240036013A1

公开(公告)日：2024-02-01

申请号：US18268314

申请日：2021-12-18

申请人： Peking University

发明人： Xinshan Ye ,  Wenlong Yao ,  Decai Xiong

IPC分类号： G01N30/24 ,  G01N30/20 ,  G01N30/30

CPC分类号： G01N30/24 ,  G01N30/20 ,  G01N30/30

摘要： An automated solution-phase synthesizer is provided with an automatic sample injection system, an assisting system for solution-phase synthesis, an automatic online monitoring system for solution-phase synthesis and a master computer. The automatic sample injection system completes an automatic sample injection operation according to a sample injection instruction from the master computer. The assisting system for solution-phase synthesis controls temperature and illumination of a solution to undergo reaction according to a temperature control instruction and an illumination control instruction from the master computer. The automatic online monitoring system for solution-phase synthesis monitors a reaction solution and generates a monitoring report. And, the master computer generates an experimental analysis result according to the monitoring report. In this way, an automatic process from sample injection to report generation in a solution-phase experiment process is completed, and further experimental labor cost is reduced and experimental efficiency is improved.

公开(公告)号：US11885775B2

公开(公告)日：2024-01-30

申请号：US16977499

申请日：2018-12-27

申请人： SHIMADZU CORPORATION

发明人： Daiki Fukushima

IPC分类号： G01N30/24 ,  G01N1/22 ,  G01N30/18 ,  G01N30/02

CPC分类号： G01N30/24 ,  G01N1/22 ,  G01N30/18 ,  G01N2030/025

摘要： In a sample injection device (100), a controller (23) is configured or programmed to control a syringe drive (21) such that in a penetration operation in which a syringe (10) is moved to a side of a sample introduction portion (910) and a needle (11) penetrates a lid member (911), a moving speed at a time when a tip (11b) of the needle contacts the lid member is a second moving speed that is low.

公开(公告)号：US20240011957A1

公开(公告)日：2024-01-11

申请号：US18037714

申请日：2021-11-19

申请人： Agilent Technologies, Inc.

发明人： Dominik Ruf ,  Thomas Ortmann

IPC分类号： G01N30/86 ,  G01N30/24 ,  G01N30/32

CPC分类号： G01N30/8658 ,  G01N30/24 ,  G01N30/32 ,  G01N2030/027

摘要： A sampling unit is fluidically coupled to a source. The sampling unit is configured for receiving a fluidic sample from the source and chromatographically separating the received fluidic sample. The sampling unit is operated to introduce a test sample into the source. At least a portion of the introduced test sample from the source is received into the sampling unit, and the received portion of the test sample is chromatographically separated in the sampling unit.

公开(公告)号：US11867669B2

公开(公告)日：2024-01-09

申请号：US17715849

申请日：2022-04-07

申请人： DIONEX SOFTRON GMBH

发明人： Thomas Wachinger

IPC分类号： G01N30/20 ,  G01N30/24

CPC分类号： G01N30/20 ,  G01N30/24 ,  G01N2030/201 ,  G01N2030/202

摘要： A sampler for liquid chromatography is described. The sampler includes an injection valve and a sample loop. The injection valve includes one waste port, two sample loop ports, and two high-pressure ports. The sample loop port includes a first loop part and a second loop part. The injection valve can be configured to have LOAD position and INJECT position. The injection valve can also be configured to have one or more additional positions such as a FULL PURGE position, a PUMP PURGE position, and a NEGATIVE PRESSURE position.

公开(公告)号：US20230408482A1

公开(公告)日：2023-12-21

申请号：US17981514

申请日：2022-11-07

申请人： Institute of Geology and Geophysics, Chinese Academy of Sciences

发明人： Jianming HE ,  Shouding LI ,  Xiao LI ,  Zhaobin ZHANG

IPC分类号： G01N33/24 ,  G01N30/24 ,  G01N30/06

CPC分类号： G01N33/241 ,  G01N2030/025 ,  G01N30/06 ,  G01N30/24

摘要： A test system and a test method for replacing natural gas hydrate with carbon dioxide are disclosed, relating to the technical field of exploitation of natural gas hydrates. The test system comprises a sample reaction vessel, a sample boundary condition loading device, a methane gas supply device, a carbon dioxide gas supply device, an output article collection and measurement device, and a data acquisition control device. A sample-sealing rubber sleeve and an upper sample-sealing plate are arranged in an inner cavity of the vessel, the sample-sealing rubber sleeve, a lower tray and the upper sample-sealing plate form a sample-sealing space. An axial pressure loading plate is arranged on the upper sample-sealing plate, and an upper cover plate is provided with an axial pressure loading injection hole. A side shrouding is provided with a confining pressure loading injection hole and a product discharge hole.