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公开(公告)号:US09528989B2
公开(公告)日:2016-12-27
申请号:US13436371
申请日:2012-03-30
申请人: Thaddeus C. George , David A. Basiji , Keith Frost , Brian E. Hall , William E. Ortyn , Michael J. Seo
发明人: Thaddeus C. George , David A. Basiji , Keith Frost , Brian E. Hall , William E. Ortyn , Michael J. Seo
IPC分类号: G06K9/00 , G01N33/569
CPC分类号: G01N33/56966
摘要: The use of an imaging system, cell compartment markers, and molecular markers in methods for correlating the movement of molecules within a cell to a particular compartment are provided, including measuring and correlating molecule movement in adherent and non-adherent cells.
摘要翻译: 提供了在将细胞内的分子运动与特定隔室相关联的方法中使用成像系统,细胞室标记和分子标记,包括测量和关联粘附和非贴壁细胞中的分子运动。
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公开(公告)号:US20120328177A1
公开(公告)日:2012-12-27
申请号:US13460682
申请日:2012-04-30
申请人: Thaddeus C. George , David A. Basiji , Brian E. Hall , William E. Ortyn , Michael J. Seo , Philip J. Morrissey , Cathleen A. Zimmerman
发明人: Thaddeus C. George , David A. Basiji , Brian E. Hall , William E. Ortyn , Michael J. Seo , Philip J. Morrissey , Cathleen A. Zimmerman
IPC分类号: G06K9/62
CPC分类号: G01N21/53 , G01N15/14 , G01N15/1475 , G01N21/6428 , G01N21/645 , G01N21/6456 , G01N2021/6423 , G01N2021/6439 , G01N2021/6482
摘要: Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.
摘要翻译: 提供了用于确定和分析小物体(诸如识别不同细胞状态的细胞)的光度和形态特征的方法。 特别地,提供了用于鉴定凋亡细胞的方法,并且用于区分经历细胞凋亡的细胞与坏死。
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公开(公告)号:US08103080B2
公开(公告)日:2012-01-24
申请号:US10593016
申请日:2005-03-16
申请人: Thaddeus C George , David A Basiji , Brian E Hall , William E Ortyn , Michael J Seo , Philip J Morrissey , Cathleen A Zimmerman
发明人: Thaddeus C George , David A Basiji , Brian E Hall , William E Ortyn , Michael J Seo , Philip J Morrissey , Cathleen A Zimmerman
IPC分类号: G06K9/00
CPC分类号: G06K9/00127 , G01N15/1475 , G01N21/47 , G01N21/645 , G01N21/6456 , G01N2021/6423 , G01N2021/6439 , G01N2021/6482 , G06K9/00147
摘要: Provided are methods for determining and analyzing photometric and morphogenic features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.
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公开(公告)号:US08953866B2
公开(公告)日:2015-02-10
申请号:US13460682
申请日:2012-04-30
申请人: Thaddeus C. George , David A. Basiji , Brian E. Hall , William E. Ortyn , Michael J. Seo , Philip J. Morrissey , Cathleen A. Zimmerman
发明人: Thaddeus C. George , David A. Basiji , Brian E. Hall , William E. Ortyn , Michael J. Seo , Philip J. Morrissey , Cathleen A. Zimmerman
CPC分类号: G01N21/53 , G01N15/14 , G01N15/1475 , G01N21/6428 , G01N21/645 , G01N21/6456 , G01N2021/6423 , G01N2021/6439 , G01N2021/6482
摘要: Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.
摘要翻译: 提供了用于确定和分析小物体(诸如识别不同细胞状态的细胞)的光度和形态特征的方法。 特别地,提供了用于鉴定凋亡细胞的方法,并且用于区分经历细胞凋亡的细胞与坏死。
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公开(公告)号:US20120244550A1
公开(公告)日:2012-09-27
申请号:US13436371
申请日:2012-03-30
申请人: Thaddeus C. George , David A. Basiji , Keith Frost , Brian E. Hall , William E. Ortyn , Michael J. Seo
发明人: Thaddeus C. George , David A. Basiji , Keith Frost , Brian E. Hall , William E. Ortyn , Michael J. Seo
CPC分类号: G01N33/56966
摘要: The use of an imaging system, cell compartment markers, and molecular markers in methods for correlating the movement of molecules within a cell to a particular compartment are provided, including measuring and correlating molecule movement in adherent and non-adherent cells.
摘要翻译: 提供了在将细胞内的分子运动与特定隔室相关联的方法中使用成像系统,细胞室标记和分子标记,包括测量和关联粘附和非贴壁细胞中的分子运动。
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公开(公告)号:US20110280467A1
公开(公告)日:2011-11-17
申请号:US13191270
申请日:2011-07-26
申请人: Thaddeus C. George , David A. Basiji , Brian E. Hall , William E. Ortyn , Michael J. Seo , Philip J. Morrissey , Cathleen A. Zimmerman
发明人: Thaddeus C. George , David A. Basiji , Brian E. Hall , William E. Ortyn , Michael J. Seo , Philip J. Morrissey , Cathleen A. Zimmerman
IPC分类号: G06K9/00
CPC分类号: G06K9/00127 , G01N15/1475 , G01N21/47 , G01N21/645 , G01N21/6456 , G01N2021/6423 , G01N2021/6439 , G01N2021/6482 , G06K9/00147
摘要: Provided are methods for determining and analyzing photometric and morphogenic features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.
摘要翻译: 提供了用于确定和分析小物体(例如,识别不同细胞状态的细胞)的光度和形态特征的方法。 特别地,提供了用于鉴定凋亡细胞的方法,并且用于区分经历细胞凋亡的细胞与坏死。
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公开(公告)号:US08175371B2
公开(公告)日:2012-05-08
申请号:US13191270
申请日:2011-07-26
申请人: Thaddeus C. George , David A. Basiji , Brian E. Hall , William E. Ortyn , Michael E. Seo , Phillip J. Morrissey , Cathleen A. Zimmerman
发明人: Thaddeus C. George , David A. Basiji , Brian E. Hall , William E. Ortyn , Michael E. Seo , Phillip J. Morrissey , Cathleen A. Zimmerman
IPC分类号: G06K9/00
CPC分类号: G06K9/00127 , G01N15/1475 , G01N21/47 , G01N21/645 , G01N21/6456 , G01N2021/6423 , G01N2021/6439 , G01N2021/6482 , G06K9/00147
摘要: Provided are methods for determining and analyzing photometric and morphogenic features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.
摘要翻译: 提供了用于确定和分析小物体(例如,识别不同细胞状态的细胞)的光度和形态特征的方法。 特别地,提供了用于鉴定凋亡细胞的方法,并且用于区分经历细胞凋亡的细胞与坏死。
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公开(公告)号:US08150136B2
公开(公告)日:2012-04-03
申请号:US10593018
申请日:2005-03-16
申请人: Thaddeus C. George , David A. Basiji , Keith Frost , Brian E. Hall , William E. Ortyn , Michael J. Seo
发明人: Thaddeus C. George , David A. Basiji , Keith Frost , Brian E. Hall , William E. Ortyn , Michael J. Seo
IPC分类号: G06K9/00
CPC分类号: G01N33/56966
摘要: The use of an imaging system, cell compartment markers, and molecular markers in methods for correlating the movement of molecules within a cell to a particular compartment are provided, including measuring and correlating molecule movement in adherent and non-adherent cells.
摘要翻译: 提供了在将细胞内的分子运动与特定隔室相关联的方法中使用成像系统,细胞室标记和分子标记,包括测量和关联粘附和非贴壁细胞中的分子运动。
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公开(公告)号:US20090202130A1
公开(公告)日:2009-08-13
申请号:US10593018
申请日:2005-03-16
申请人: Thaddeus C. George , David A. Basiji , Keith Frost , Brian E. Hall , William E. Ortyn , Michael J. Seo
发明人: Thaddeus C. George , David A. Basiji , Keith Frost , Brian E. Hall , William E. Ortyn , Michael J. Seo
IPC分类号: G06K9/00
CPC分类号: G01N33/56966
摘要: The use of an imaging system, cell compartment markers, and molecular markers in methods for correlating the movement of molecules within a cell to a particular compartment are provided, including measuring and correlating molecule movement in adherent and non-adherent cells.
摘要翻译: 提供了在将细胞内的分子运动与特定隔室相关联的方法中使用成像系统,细胞室标记和分子标记,包括测量和关联粘附和非贴壁细胞中的分子运动。
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公开(公告)号:US08571294B2
公开(公告)日:2013-10-29
申请号:US13302941
申请日:2011-11-22
申请人: Thaddeus C. George , David A. Basiji , Brian E. Hall , William E. Ortyn , Michael E. Seo , Phillip J. Morrissey , Cathleen A. Zimmerman
发明人: Thaddeus C. George , David A. Basiji , Brian E. Hall , William E. Ortyn , Michael E. Seo , Phillip J. Morrissey , Cathleen A. Zimmerman
IPC分类号: G06K9/00
CPC分类号: G06K9/00127 , G01N15/1475 , G01N21/47 , G01N21/645 , G01N21/6456 , G01N2021/6423 , G01N2021/6439 , G01N2021/6482 , G06K9/00147
摘要: Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing between cells undergoing apoptosis versus necrosis.
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